Researchers sought to determine the effects and cerebrospinal fluid concentrations of treatment with bictegravir, emtricitabine, and tenofovir in patients with HIV-related central nervous system impairment.

All articles by Sweta Gupta
An interim phase 3 trial shows promising results for the Russian heterologous recombinant adenovirus-based SARS-CoV-2 vaccine.
Researchers assessed if use of intravenous remdesivir in hospitalized patients with coronavirus disease 2019 infection affected time to recovery and clinical status on days 15 and 29.
Although the prevalence of distal sensory peripheral neuropathy decreased following initiation of cART in people living with in resource-limiting settings, better strategies are needed.
Beneficial changes in microbial composition and functionality with capsular fecal microbiota transplant lead to improved cognition in patients with cirrhosis and recurrent hepatic encephalopathy.
Researchers highlighted the need for rapid investigations of vaccine safety concerns to use robust epidemiologic methods to maintain public and professional confidence in vaccination programs.
Antisense oligonucleotide drug HTTRx reduced the concentration of mutant huntingtin protein in the cerebrospinal fluid of persons with Huntington disease.
Long-term effect of eculizumab in patients with neuromyelitis optica spectrum disorder warrants further study, since there was no significant between-group difference in measures of disability progression.
Hematocrit levels and presence of erythrocytosis were associated with awake and nocturnal hypoxemia, according to the study.
Increased risk of pediatric multiple sclerosis was observed in patients with prior exposure to EBV, HSV-1, and vitamin D deficiency.
Sepsis is associated with pathways that lead to permanent neurological sequelae.
People with HBV were 76% more likely and those with HCV were 51% more likely to develop PD than people in the comparison group.
Patients were 10% to 30% less likely to acquire a multidrug-resistant organism or C difficile if enhanced disinfection strategies were used in hospitals.
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