Generic Name and Formulations:
Baclofen 10mg, 20mg; scored tabs.
Various generic manufacturers
Indications for Baclofen:
Spasticity associated with MS and spinal cord injury or disease.
5mg 3 times daily. Increase in increments of 5mg 3 times daily every 3 days if needed; max 80mg daily. Use lowest dose possible.
Impaired renal function. Beneficial spasticity. Stroke. Epilepsy. Avoid abrupt cessation. Pregnancy. Nursing mothers.
Muscle relaxant (central).
Alcohol and other CNS depressants potentiated.
Transient drowsiness, confusion, dizziness, weakness, fatigue, headache, hypotension, nausea, increased urinary frequency; seizures and hallucinations on abrupt withdrawal.
Formerly known under the brand names Kemstro, Lioresal.
Neurology Advisor Articles
- Gender and Multiple Sclerosis: How It Influences Prognosis and Future Treatment
- Significant Variations in Epilepsy Surgical Strategy, Deficit Reporting Exist
- Thrombolysis With Tenecteplase Is as Safe as Alteplase in Stroke Mimics
- Loss of Function Variants in LRRK1 and LRRK2 Not Linked to Parkinson Disease
- Smoking Promotes Disease Progression in Multiple Sclerosis
- 5 Key Findings Presented at 2018 Parkinson Disease Conference
- Parkinson Disease and the Gut: Treatment Potential Abounds
- Managing Comorbid Migraine and Mood Disorders: A Synergistic Approach
- Stroke-Code Patients With Low NIHSS Score, No Acute Imaging Findings Often Misdiagnosed
- Ethical Challenges of Nusinersen: Considerations When Counseling on Treatment
- ZTlido Patch for Post-Shingles Pain Launching Soon
- Managing Complications of Intrathecal Baclofen Therapy
- Deep Brain Stimulation Reduces Tremor Symptoms in Parkinson Disease
- FDA Issues Statement Addressing Safety Concerns Associated With Nuplazid
- Prevalence of Autoimmune Encephalitis in Herpes Simplex Encephalitis Explored