Cancer

No Clear Benefit for Anticoagulants Over Antiplatelets in Stroke Patients With Cancer

No Clear Benefit for Anticoagulants Over Antiplatelets in Stroke Patients With Cancer

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This is the first clinical trial to compare antiplatelet and anticoagulation therapy in patients with cancer and ischemic stroke.

Clinical Factors Associated With Pediatric Brain Neoplasms

Clinical Factors Associated With Pediatric Brain Neoplasms

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A study pinpointed clinical factors associated with pediatric brain neoplasms to assist clinicians in making neuroimaging decisions.

Seizure Incidence Stable in Prostate Cancer Treated With Enzalutamide

Seizure Incidence Stable in Prostate Cancer Treated With Enzalutamide

Treatment with enzalutamide for metastatic castration-resistant prostate cancer patients is not linked with increased seizure incidence.

Temozolomide Plus Radiotherapy Improves Survival in Non-Co-Deleted Glioma

Temozolomide Plus Radiotherapy Improves Survival in Non-Co-Deleted Glioma

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1p/19q non-co-deleted anaplastic gliomas are associated with lower sensitivity to chemotherapy and worse prognosis than 1p/19q co-deleted tumors.

Characteristics of Neurotoxicity After CD19 CAR-T Cell Infusion

Characteristics of Neurotoxicity After CD19 CAR-T Cell Infusion

Patients with severe neurotoxicity have evidence of endothelial activation.

PD-1 Therapy for Cancer Increases Risk for Neurological Complications

PD-1 Therapy for Cancer Increases Risk for Neurological Complications

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The clinical spectrum and optimal treatment approach for PD-1-related neurological complications is not clear.

Immunosuppressant Use May Increase Cancer Risk in Multiple Sclerosis

Immunosuppressant Use May Increase Cancer Risk in Multiple Sclerosis

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It is important to consider long-term risks and outcomes when choosing an appropriate therapy for multiple sclerosis.

Cognitive Impairment Not Common Post-Skull Radiation

Cognitive Impairment Not Common Post-Skull Radiation

Most patients undergoing skull base irradiation for cancer do not have detectable cognitive impairment.

Postoperative Stereotactic Radiosurgery Reduces Recurrence After Metastases Resection

Postoperative Stereotactic Radiosurgery Reduces Recurrence After Metastases Resection

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The use of postoperative stereotactic radiosurgery could be a substitute for whole-brain radiotherapy, which has been linked to cognitive adverse effects.

Stroke Prevention Therapy Safe, Effective for Cancer Patients

Stroke Prevention Therapy Safe, Effective for Cancer Patients

Rivaroxaban treatment for nonvalvular AF in patients with cancer is safe.

Parkinson's Patients May Face Greater Risk of Melanoma

Parkinson's Patients May Face Greater Risk of Melanoma

There is a 4 times greater risk of developing melanoma in Parkinson's disease, and vice versa.

Researchers Debunk Rumored Link Between Glioblastoma, Cytomegalovirus

Researchers Debunk Rumored Link Between Glioblastoma, Cytomegalovirus

Despite previous reports, researchers have found no signs of a link between cytomegalovirus and brain tumors including glioblastoma.

Post-Chemo Cognitive Impairment Apparent in Breast Cancer Survivors

Post-Chemo Cognitive Impairment Apparent in Breast Cancer Survivors

Patients reported significant cognitive difficulties from pre-chemotherapy to post-chemotherapy and from pre-chemotherapy to 6-month follow-up.

HER2-Negative Breast Cancer Turns Positive in the Brain

HER2-Negative Breast Cancer Turns Positive in the Brain

Molecular changes occur to cancer cells when they spread to the brain.

Stereotactic Radiosurgery Alone Better for Cognition in Brain Metastases

Stereotactic Radiosurgery Alone Better for Cognition in Brain Metastases

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Intracranial disease control at 3 months was better with combination therapy; however it did not appear to impact overall survival.

Delirium Common Yet Underdiagnosed in Cancer Patients

Delirium Common Yet Underdiagnosed in Cancer Patients

The researchers found evidence of several psychoactive drugs, which may contribute to delirium.

Exercise May Reduce Stress, Boost Memory in Cancer Survivors

Exercise May Reduce Stress, Boost Memory in Cancer Survivors

Impairments in memory after cancer treatment might be more emotional, the researchers suggest.

Monitoring Chemo-Induced Peripheral Neuropathy May Help Reduce Fall Risk

Monitoring Chemo-Induced Peripheral Neuropathy May Help Reduce Fall Risk

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Remote monitoring of symptoms can help clinicians keep track of patients' status.

Mitoxantrone Linked to Elevated Cancer Risk in Multiple Sclerosis Patients

Mitoxantrone Linked to Elevated Cancer Risk in Multiple Sclerosis Patients

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The drug was previously linked to an elevated risk of acute myeloid leukemia.

Peripheral Neuropathy In Cancer Patients Linked to Vitamin D

Peripheral Neuropathy In Cancer Patients Linked to Vitamin D

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The severity of peripheral neuropathy is associated with lower vitamin D levels in patients with multiple myeloma.

Brain Tumor Histology and Incidence in Adolescents and Young Adults

Brain Tumor Histology and Incidence in Adolescents and Young Adults

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Over 10 000 brain and CNS tumors are diagnosed in adolescent and young adults each year.

Mindfulness Therapy Improves Post-Cancer Cognition

Mindfulness Therapy Improves Post-Cancer Cognition

Mindfulness-based stress reduction helped to improve post-cancer treatment cognitive function.

Androgen Deprivation Therapy Significantly Increases Alzheimer's Risk

Androgen Deprivation Therapy Significantly Increases Alzheimer's Risk

Those treated with ADT for over one year had double the risk compared to patients who did not receive the therapy.

Anthracycline-Based Chemo Affects Cognition, Brain Connectivity

Anthracycline-Based Chemo Affects Cognition, Brain Connectivity

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Anthracycline-based chemotherapy was associated with worse cognitive outcomes than nonanthracycline chemo.

Chemotherapy-Induced Peripheral Neuropathy Common, but Underdiagnosed

Chemotherapy-Induced Peripheral Neuropathy Common, but Underdiagnosed

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As many as 50% of neurotoxic chemotherapy patients experience CPN.

Pediatric Cancer Survivors At High Risk for Second Stroke

Pediatric Cancer Survivors At High Risk for Second Stroke

The risk of suffering a second stroke is double the rate seen in noncancer stroke survivors.

Parkinson's Disease May Be Linked with Cancer Risk

Parkinson's Disease May Be Linked with Cancer Risk

Parkinson's disease may be associated with a higher risk of most cancers.

Growing Number of Cancer Patients Interested in Genetic Profiling

Growing Number of Cancer Patients Interested in Genetic Profiling

Many are willing to pay out of pocket for the test.

Cancer 'Neuroinvasion' Plays Role in Cancer Pain, Progression

Cancer 'Neuroinvasion' Plays Role in Cancer Pain, Progression

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In addition to contributing significantly to cancer pain, researchers believe cancer progression depends largely on nerve activity.

Enoxaparin Effective for Venous Thromboembolism in Pancreatic Cancer

Enoxaparin Effective for Venous Thromboembolism in Pancreatic Cancer

Enoxaparin was effective in preventing VTEs with no adverse effect on major bleeding or chemo efficacy.

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