Cognitive Impairment

Nonlanguage Mathematical, Visuospatial Learning Disabilities Likely in Focal Neurodegenerative Syndromes

Nonlanguage Mathematical, Visuospatial Learning Disabilities Likely in Focal Neurodegenerative Syndromes

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Individual patients with PCA and LDs demonstrated more right-lateralized patterns of atrophy and greater preservation of global cognition compared with patients with PCA without LDs.

Handgrip Strength Predicts Cognitive Function in Bipolar Disorder, Major Depression

Handgrip Strength Predicts Cognitive Function in Bipolar Disorder, Major Depression

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Handgrip strength was significantly associated with improved visual memory reaction time, prospective memory, and reasoning in patients with bipolar disorder.

Trintellix Labeling Updated With Data on Improved Processing Speed in MDD

Trintellix Labeling Updated With Data on Improved Processing Speed in MDD

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Lundbeck announced that the FDA has approved a sNDA for Trintellix to include data regarding improved processing speed.

Annual Visits May Not Increase Cognitive Impairment Detection

Annual Visits May Not Increase Cognitive Impairment Detection

Medicare Annual Wellness Visits do not appear to substantially increase the detection of cognitive impairment in older adults.

Small Link for Cannabis Use, Reduced Cognitive Functioning

Small Link for Cannabis Use, Reduced Cognitive Functioning

For adolescents and young adults, frequent or heavy cannabis use has a small association with reduced cognitive functioning.

Hearing Aids May Mitigate Cognitive Decline, Memory Loss

Hearing Aids May Mitigate Cognitive Decline, Memory Loss

Using hearing aids may slow cognitive decline in later life.

MIND Diet Linked to Slower Cognitive Decline Among Stroke Survivors

MIND Diet Linked to Slower Cognitive Decline Among Stroke Survivors

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The MIND diet, a combination of the Mediterranean and DASH diets, was associated with a slower rate of cognitive decline among stroke survivors.

Untrimmed Toenails: A Marker of Functional Status in Older Patients?

Untrimmed Toenails: A Marker of Functional Status in Older Patients?

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For older patients, toenail length can provide important insight into a patient's functional status.

Assessing and Treating Cognitive, Mood Impairments in Patients With Stroke

Assessing and Treating Cognitive, Mood Impairments in Patients With Stroke

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The ultimate goal of stroke assessment is to enable physicians to make treatment decisions that are individualized and appropriate to the patient's needs, thereby improving patient outcomes.

Retinopathy Associated With Greater Risk for 20-Year Cognitive Decline

Retinopathy Associated With Greater Risk for 20-Year Cognitive Decline

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Retinopathy as well as an overall loss of vascular integrity was significantly associated with a greater 20-year cognitive decline after controlling for attrition.

Hormone Therapy May Impact Brain Structure, Cognition

Hormone Therapy May Impact Brain Structure, Cognition

3 years after menopausal HT, change in brain volumes were not significantly different from placebo.

High Total Cholesterol Neuroprotective Against Cognitive Decline

High Total Cholesterol Neuroprotective Against Cognitive Decline

For older adults with high cholesterol, the risk for cognitive decline is reduced.

Cognitive Decline in Men Linked to Low Serum Sodium

Cognitive Decline in Men Linked to Low Serum Sodium

For community-dwelling older men, low serum sodium is associated with cognitive impairment and cognitive decline.

Solanezumab Has No Effect on Cognitive Decline in Alzheimer Disease

Solanezumab Has No Effect on Cognitive Decline in Alzheimer Disease

Solanezumab does not alter cognitive decline in patients with mild Alzheimer disease.

Lifestyle Intervention May Improve Cognition in APOEε4 Carriers

Lifestyle Intervention May Improve Cognition in APOEε4 Carriers

In older at-risk individuals, even APOE ε4 carriers, a multidomain lifestyle intervention seems to be beneficial.

Elderly With Cognitive Impairment More Likely to Experience Falls

Elderly With Cognitive Impairment More Likely to Experience Falls

Cognitive therapies may help reduce falls in order adults.

No Cognitive Improvement With Idalopirdine in Mild Alzheimer Disease

No Cognitive Improvement With Idalopirdine in Mild Alzheimer Disease

For patients with mild-to-moderate Alzheimer disease, the use of idalopirdine does not improve cognition.

Guidelines: AAN Recommends Exercise, Cautious Prescribing for Patients With Mild Cognitive Impairment

Guidelines: AAN Recommends Exercise, Cautious Prescribing for Patients With Mild Cognitive Impairment

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A lower education level was associated with higher MCI prevalence in 8 of the class I studies.

Subcortical Microinfarcts Associated With Decreased Blood Pressure in Elderly

Subcortical Microinfarcts Associated With Decreased Blood Pressure in Elderly

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Greater yearly declines in systolic and diastolic blood pressure were noted in individuals with subcortical microinfarcts.

Risk for Cognitive Decline, Dementia Linked to Age-Related Hearing Loss

Risk for Cognitive Decline, Dementia Linked to Age-Related Hearing Loss

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Clinicians might benefit from standard guidelines on how to assess and refer patients with hearing loss.

Increasing Leafy Vegetable Intake May Boost Cognition

Increasing Leafy Vegetable Intake May Boost Cognition

Intake of nutrients in green leafy vegetables is linked to a slower cognitive decline.

Predicting Risk for Cognitive Impairment Based on Age, Mini-Mental Exam

Predicting Risk for Cognitive Impairment Based on Age, Mini-Mental Exam

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Charts may help identify individuals who may benefit most from early interventions to help preserve cognition.

Amyloid, Tau Patterns in Parkinson's Do Not Differ Based on Cognitive Status

Amyloid, Tau Patterns in Parkinson's Do Not Differ Based on Cognitive Status

In Parkinson's patients who are cognitively normal or have mild cognitive impairment, patterns of cortical β-amyloid and tau are not different.

Obesity and Alzheimer Disease: Exploring Risk Modification

Obesity and Alzheimer Disease: Exploring Risk Modification

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Throughout the life course, higher body mass index and obesity are linked to cognitive decline, brain atrophy, reduced white matter and integrity of the blood-brain barrier, and elevated risk for late-onset Alzheimer disease.

Anticholinergic Cognitive Burden Scale Identifies Dose-Related Adverse Outcomes

Anticholinergic Cognitive Burden Scale Identifies Dose-Related Adverse Outcomes

The ACB scale shows good dose-response relationships between anticholinergic burden and adverse outcomes for older adults.

Predicting Risk of Cognitive Decline With Nocturnal Sleep Blood Pressure

Predicting Risk of Cognitive Decline With Nocturnal Sleep Blood Pressure

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An approximately 1-SD increase in SBP correlated with lower scores for 2 tests that assessed for brain damage, dementia, and task switching.

Cognitive Impairment in Multi-System Atrophy: Is It Time to Update Diagnostic Criteria?

Cognitive Impairment in Multi-System Atrophy: Is It Time to Update Diagnostic Criteria?

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Although evidence of cognitive impairment in MSA is admittedly more limited than in Parkinson disease, it is now substantial enough to address modification of diagnostic criteria to include the potential for cognitive impairment at any stage of the disease.

Subjective Cognitive Decline Associated With Tauopathy and Global β-Amyloid Burden

Subjective Cognitive Decline Associated With Tauopathy and Global β-Amyloid Burden

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Multiple biological factors may play a role when cognitive decline is observed in older health adults.

Parkinsonism Diagnosis Linked to Cognitive Deficits

Parkinsonism Diagnosis Linked to Cognitive Deficits

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Cognitive dysfunction may be a sign of prodromal Parkinson disease.

Atrial Fibrillation Associated With Cognitive Decline

Atrial Fibrillation Associated With Cognitive Decline

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Mechanisms including silent cerebral infarct, microemboli, microbleedings, and cerebral hypoperfusion may be responsible for the link between atrial fibrillation and cognitive decline.

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