Cognitive Impairment

Living in Deprived Area Is Risk Factor for Cognitive Dysfunction

Living in Deprived Area Is Risk Factor for Cognitive Dysfunction

Area-level deprivation is an independent risk factor for cognitive dysfunction in older adults.

Details of Montreal Cognitive Assessment Widely Publicized

Details of Montreal Cognitive Assessment Widely Publicized

Many published news articles included details of the MoCA in association with President Trump, some of which invited readers to self-administer the test.

Promising Improvements in Mild Cognitive Impairment With Investigational NA-831

Promising Improvements in Mild Cognitive Impairment With Investigational NA-831

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Researchers from NeuroActiva, Inc. presented results of their randomized, double-blind, placebo-controlled phase 2A clinical trial of NA-831.

Declines in Vision Tied to Age-Related Cognitive Decline

Declines in Vision Tied to Age-Related Cognitive Decline

Older adults' worsening vision may drive declines in cognitive function.

Depression, Apathy Associated With Increased Risk for Mild Cognitive Impairment

Depression, Apathy Associated With Increased Risk for Mild Cognitive Impairment

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Adults with depressive symptoms and apathy in middle and late life were at a higher risk for conversion to mild cognitive impairment (MCI) and dementia.

11.2% of U.S. Adults Aged ≥45 Report Subjective Mental Decline

11.2% of U.S. Adults Aged ≥45 Report Subjective Mental Decline

More than 11% of adults aged ≥45 years in the United States report subjective cognitive decline.

Midlife Cognition, Vascular Health Predict Dementia and Cognitive Impairment Later in Life

Midlife Cognition, Vascular Health Predict Dementia and Cognitive Impairment Later in Life

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Investigators reviewed data from patients aged 45 to 64 years who were enrolled in the Atherosclerosis Risk in Communities Study and who attended additional visits for cognitive function evaluation and repeat cardiovascular risk factor assessment.

In Children, Food Insecurity Tied to Behavior, Cognition

In Children, Food Insecurity Tied to Behavior, Cognition

Food insecurity may be linked to behavioral problems and poorer cognitive performance in children.

Thinner Retinal Nerve Fiber Layer Tied to Worse Cognitive Function

Thinner Retinal Nerve Fiber Layer Tied to Worse Cognitive Function

For individuals without neurodegenerative disease, a thinner retinal nerve fiber layer is associated with worse cognitive function.

Long-Term Type 1 Diabetes Associated With Cognitive Decline

Long-Term Type 1 Diabetes Associated With Cognitive Decline

Both patients with type 1 and patients with type 2 diabetes show overall worse cognition than people without diabetes.

Review IDs Exercise 'Dose' That May Improve Cognition in Seniors

Review IDs Exercise 'Dose' That May Improve Cognition in Seniors

For older adults, exercise is associated with improved cognition.

Higher HDL-C Linked to Better Cognition in Older DM Patients

Higher HDL-C Linked to Better Cognition in Older DM Patients

Higher serum HDL-C is associated with better executive function among older patients with diabetes mellitus.

Amyloid Positivity Increases Risk for Cognitive Impairment in Dementia-Free Patients

Amyloid Positivity Increases Risk for Cognitive Impairment in Dementia-Free Patients

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The findings from the study are limited in generalizability to the dementia-free patient population.

Aerobic and Strength Exercise Doesn't Slow Cognitive Decline

Aerobic and Strength Exercise Doesn't Slow Cognitive Decline

An aerobic and strength exercise program does not slow cognitive impairment among people with mild-to-moderate dementia.

Nonlanguage Mathematical, Visuospatial Learning Disabilities Likely in Focal Neurodegenerative Syndromes

Nonlanguage Mathematical, Visuospatial Learning Disabilities Likely in Focal Neurodegenerative Syndromes

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Individual patients with PCA and LDs demonstrated more right-lateralized patterns of atrophy and greater preservation of global cognition compared with patients with PCA without LDs.

Handgrip Strength Predicts Cognitive Function in Bipolar Disorder, Major Depression

Handgrip Strength Predicts Cognitive Function in Bipolar Disorder, Major Depression

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Handgrip strength was significantly associated with improved visual memory reaction time, prospective memory, and reasoning in patients with bipolar disorder.

Trintellix Labeling Updated With Data on Improved Processing Speed in MDD

Trintellix Labeling Updated With Data on Improved Processing Speed in MDD

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Lundbeck announced that the FDA has approved a sNDA for Trintellix to include data regarding improved processing speed.

Annual Visits May Not Increase Cognitive Impairment Detection

Annual Visits May Not Increase Cognitive Impairment Detection

Medicare Annual Wellness Visits do not appear to substantially increase the detection of cognitive impairment in older adults.

Small Link for Cannabis Use, Reduced Cognitive Functioning

Small Link for Cannabis Use, Reduced Cognitive Functioning

For adolescents and young adults, frequent or heavy cannabis use has a small association with reduced cognitive functioning.

Hearing Aids May Mitigate Cognitive Decline, Memory Loss

Hearing Aids May Mitigate Cognitive Decline, Memory Loss

Using hearing aids may slow cognitive decline in later life.

MIND Diet Linked to Slower Cognitive Decline Among Stroke Survivors

MIND Diet Linked to Slower Cognitive Decline Among Stroke Survivors

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The MIND diet, a combination of the Mediterranean and DASH diets, was associated with a slower rate of cognitive decline among stroke survivors.

Untrimmed Toenails: A Marker of Functional Status in Older Patients?

Untrimmed Toenails: A Marker of Functional Status in Older Patients?

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For older patients, toenail length can provide important insight into a patient's functional status.

High CSF Neurogranin Associated With Faster Decline in Mild Cognitive Impairment

High CSF Neurogranin Associated With Faster Decline in Mild Cognitive Impairment

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Investigators obtained data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database on patients with normal cognition (n=111) and MCI (n=193), all of whom had CSF Ng samples at baseline as well as memory and executive function evaluations at follow-up.

Assessing and Treating Cognitive, Mood Impairments in Patients With Stroke

Assessing and Treating Cognitive, Mood Impairments in Patients With Stroke

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The ultimate goal of stroke assessment is to enable physicians to make treatment decisions that are individualized and appropriate to the patient's needs, thereby improving patient outcomes.

Retinopathy Associated With Greater Risk for 20-Year Cognitive Decline

Retinopathy Associated With Greater Risk for 20-Year Cognitive Decline

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Retinopathy as well as an overall loss of vascular integrity was significantly associated with a greater 20-year cognitive decline after controlling for attrition.

Hormone Therapy May Impact Brain Structure, Cognition

Hormone Therapy May Impact Brain Structure, Cognition

3 years after menopausal HT, change in brain volumes were not significantly different from placebo.

High Total Cholesterol Neuroprotective Against Cognitive Decline

High Total Cholesterol Neuroprotective Against Cognitive Decline

For older adults with high cholesterol, the risk for cognitive decline is reduced.

Tau PET a Useful Biomarker for Alzheimer Disease Risk and Progression

Tau PET a Useful Biomarker for Alzheimer Disease Risk and Progression

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PET imaging may help clinicians track progression of the disease and evaluate response to disease-modifying treatments.

Cognitive Decline in Men Linked to Low Serum Sodium

Cognitive Decline in Men Linked to Low Serum Sodium

For community-dwelling older men, low serum sodium is associated with cognitive impairment and cognitive decline.

Factors Predictive of Mild Cognitive Impairment in Healthy Individuals

Factors Predictive of Mild Cognitive Impairment in Healthy Individuals

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Investigators sought to examine factors that influence a cognitively normal individual's risk for developing symptoms of mild cognitive impairment due to Alzheimer disease.

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