Diabetes

Type 2 Diabetes May Have Adverse Effect on Parkinson Disease Symptoms, Outcomes

Type 2 Diabetes May Have Adverse Effect on Parkinson Disease Symptoms, Outcomes

By

Patients with both Parkinson disease and type 2 diabetes were more likely to have cardiovascular comorbidities than those with only Parkinson disease.

Low Fasting Insulin Associated With Long-Term Dementia Risk

Low Fasting Insulin Associated With Long-Term Dementia Risk

By

Having high insulin at baseline was associated with a greater risk for incident diabetes mellitus compared with low insulin values.

Metformin Associated With Increased Dementia Risk in African Americans With Diabetes

Metformin Associated With Increased Dementia Risk in African Americans With Diabetes

By

Participants in this study were part of the Indianapolis-Ibadan Dementia Project that took place from 1992 to 2011 and were assessed for dementia every second or third year during follow-up.

Diabetes, Prediabetes Hasten Mental Decline in Older Adults

Diabetes, Prediabetes Hasten Mental Decline in Older Adults

By

Magnetic resonance imaging scans revealed smaller total brain tissue volume and a significant decrease in white matter volume in participants with prediabetes.

Strong Link Identified Between T2DM and Parkinson Disease

Strong Link Identified Between T2DM and Parkinson Disease

There is an increased rate of subsequent Parkinson disease among individuals diagnosed with type 2 diabetes mellitus.

CAPPRI Scale is Feasible for Assessing Health-Related Quality of Life in Diabetic Distal Sensorimotor Polyneuropathy

CAPPRI Scale is Feasible for Assessing Health-Related Quality of Life in Diabetic Distal Sensorimotor Polyneuropathy

By

Investigators evaluated the performance of the CAPPRI in assessing health-related quality-of-life outcomes in patients with diabetic distal sensorimotor polyneuropathy.

Long-Term Type 1 Diabetes Associated With Cognitive Decline

Long-Term Type 1 Diabetes Associated With Cognitive Decline

Both patients with type 1 and patients with type 2 diabetes show overall worse cognition than people without diabetes.

Higher HDL-C Linked to Better Cognition in Older DM Patients

Higher HDL-C Linked to Better Cognition in Older DM Patients

Higher serum HDL-C is associated with better executive function among older patients with diabetes mellitus.

Spinal Cord Stimulation Reduces Pain Associated With Diabetic Polyneuropathy

Spinal Cord Stimulation Reduces Pain Associated With Diabetic Polyneuropathy

Chronic pain symptoms in patients with PDPN are effectively reduced with spinal cord stimulation.

Metformin Linked to Reduced Dementia Risk in Veterans With Type 2 Diabetes

Metformin Linked to Reduced Dementia Risk in Veterans With Type 2 Diabetes

By

Previous research has shown an association between some oral diabetes medications and lower incidence of dementia.

Prevalence of Cardiovascular Risk Factors in Stroke on the Rise

Prevalence of Cardiovascular Risk Factors in Stroke on the Rise

By

While the increase in cardiovascular risk factors is at least partially due to the obesity epidemic, the researchers believe the increase is multifactorial.

Comparing Treatments for Painful Diabetic Neuropathy

Comparing Treatments for Painful Diabetic Neuropathy

By

Rates of painful diabetic neuropathy are increasing along with the prevalence of diabetes.

Poor Glycemic Control After Ischemic Stroke Linked to Poor Outcomes

Poor Glycemic Control After Ischemic Stroke Linked to Poor Outcomes

By

Only 16% of patients had an adequate response to conventional therapy, with patients who didn't considered "non-responders."

HbA1c, Plasma Glucose Linked to Alzheimer's in Diabetes

HbA1c, Plasma Glucose Linked to Alzheimer's in Diabetes

For T2DM patients, FPG and HbA1c are independently associated with Alzheimer's disease.

Evaluating Orexin Antagonist for Diabetic Neuropathy Tx

Evaluating Orexin Antagonist for Diabetic Neuropathy Tx

By

Researchers are looking into improving sleep in order to alleviate chronic pain.

Gabapentin Effective for Postherpetic Neuralgia, Neuropathy

Gabapentin Effective for Postherpetic Neuralgia, Neuropathy

By

Patients suffering from postherpetic nearalgia found relief taking gabapentin.

Diabetes, Obesity Linked to Cortical Atrophy

Diabetes, Obesity Linked to Cortical Atrophy

The researchers found that global mean cortical thickness was lower in the overweight/obese T2DM group.

Intensive Lifestyle Intervention Holds No Benefit for Cognitive Impairment: Analysis

Intensive Lifestyle Intervention Holds No Benefit for Cognitive Impairment: Analysis

By

An intensive lifestyle intervention including diet and exercise resulted in no improvements in cognitive impairment.

Obesity Linked to Brain Function Abnormalities in Diabetics

Obesity Linked to Brain Function Abnormalities in Diabetics

By

In addition to brain imaging, patients underwent cognitive tests to assess memory, executive function, and psychomotor speed.

Overactive Bladder Drugs Tied to Increased Dementia Risk in Diabetes

Overactive Bladder Drugs Tied to Increased Dementia Risk in Diabetes

By

Clinicians must keep this potentially increased risk in mind when prescribing long-term use of a specific anticholinergic drug to patients with DM suffering from OAB.

Insulin Resistance Affects Cognition Later in Life

Insulin Resistance Affects Cognition Later in Life

The researchers found that higher baseline HOMA-IR and fasting insulin levels were independent predictors of poorer verbal fluency performance.

Neuropathic Pain: Navigating the Challenges of an Elusive Disease

Neuropathic Pain: Navigating the Challenges of an Elusive Disease

By

As the population ages, and as both the incidence of diabetes and the survival rates after chemotherapy treatment increase, the number of patients with neuropathic pain is expected to rise.

Diabetic Neuropathy Guidelines Updated by ADA

Diabetic Neuropathy Guidelines Updated by ADA

By

New evidence on diabetic neuropathy has emerged since the ADA's last published a position statement in 2005.

Insulin-Controlled Diabetes Linked to Increased Stroke Risk in AFib

Insulin-Controlled Diabetes Linked to Increased Stroke Risk in AFib

The increased risk of stroke was only observed among patients with diabetes controlled by insulin.

Poor Sleep Quality, Short Duration May Increase Risk of Gestational Diabetes

Poor Sleep Quality, Short Duration May Increase Risk of Gestational Diabetes

By

Women who were pregnant and slept for less than 6 hours per night or had poor sleep quality had a greater risk of developing gestational diabetes.

Delayed Sleep Onset Linked to Insulin Resistance in Women

Delayed Sleep Onset Linked to Insulin Resistance in Women

By

The study supports previous findings of hyperarousal of the inflammatory system as a mechanism of insulin resistance.

Depressive Disorder in Type 2 Diabetes

Depressive Disorder in Type 2 Diabetes

By

Patients with type 2 diabetes and major depressive disorder spent a significant amount of time experiencing depressive episodes.

Ghrelin Levels May Predict Cognitive Impairment in Diabetes

Ghrelin Levels May Predict Cognitive Impairment in Diabetes

Ghrelin was a significant predictor for executive function impairment in patients with T2DM.

Pioglitazone Reduces Diabetes Risk in Patients With Ischemic Stroke

Pioglitazone Reduces Diabetes Risk in Patients With Ischemic Stroke

The findings are relevant for patients with insulin resistance but no history of diabetes.

Statins May Protect Against Parkinson's Disease in Diabetes

Statins May Protect Against Parkinson's Disease in Diabetes

By

All but one type of statin was associated with a dose-dependent neurprotective benefit against Parkinson's.

Sign Up for Free e-newsletters



CME Focus