Participants in this study were part of the Indianapolis-Ibadan Dementia Project that took place from 1992 to 2011 and were assessed for dementia every second or third year during follow-up.
Magnetic resonance imaging scans revealed smaller total brain tissue volume and a significant decrease in white matter volume in participants with prediabetes.
There is an increased rate of subsequent Parkinson disease among individuals diagnosed with type 2 diabetes mellitus.
Both patients with type 1 and patients with type 2 diabetes show overall worse cognition than people without diabetes.
Higher serum HDL-C is associated with better executive function among older patients with diabetes mellitus.
Previous research has shown an association between some oral diabetes medications and lower incidence of dementia.
While the increase in cardiovascular risk factors is at least partially due to the obesity epidemic, the researchers believe the increase is multifactorial.
Only 16% of patients had an adequate response to conventional therapy, with patients who didn't considered "non-responders."
For T2DM patients, FPG and HbA1c are independently associated with Alzheimer's disease.
The researchers found that global mean cortical thickness was lower in the overweight/obese T2DM group.
An intensive lifestyle intervention including diet and exercise resulted in no improvements in cognitive impairment.
In addition to brain imaging, patients underwent cognitive tests to assess memory, executive function, and psychomotor speed.
Clinicians must keep this potentially increased risk in mind when prescribing long-term use of a specific anticholinergic drug to patients with DM suffering from OAB.
The researchers found that higher baseline HOMA-IR and fasting insulin levels were independent predictors of poorer verbal fluency performance.
The increased risk of stroke was only observed among patients with diabetes controlled by insulin.
Women who were pregnant and slept for less than 6 hours per night or had poor sleep quality had a greater risk of developing gestational diabetes.
The study supports previous findings of hyperarousal of the inflammatory system as a mechanism of insulin resistance.
Patients with type 2 diabetes and major depressive disorder spent a significant amount of time experiencing depressive episodes.
Ghrelin was a significant predictor for executive function impairment in patients with T2DM.
The findings are relevant for patients with insulin resistance but no history of diabetes.
All but one type of statin was associated with a dose-dependent neurprotective benefit against Parkinson's.
Differences in brain volume have previously been found in adults with Type 2 diabetes.
Selective serotonin reuptake inhibitor use increases risk for patients hospitalized with stroke.
Sleep deprivation does not worsen impairment in type 1 diabetes, but prolongs recovery.
Long-term intervention was associated with lower white matter hyperintensity volume.
The risk of epilepsy is nearly 3 times greater in patients with Type 1 diabetes.
Type 2 diabetes appears to be more common in adolescents with autism spectrum disorders.
The drugs have an anti-inflammatory effect in patients with both MS and metabolic syndrome.
After 6 months, the CPAP group saw a greater decrease in HbA1c levels compared to controls.
Patients taking pioglitazone saw a 24% reduction in risk for recurrent stroke or myocardial infarction compared to placebo.
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