DiagnosticUpdate Archive - Neurology Advisor

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Fatigue in Multiple Sclerosis: Providing an Effective Diagnostic Approach

Fatigue is considered a multidimensional symptom of multiple sclerosis that remains one of the least understood and among the most difficult to diagnose and manage. This article explores current understanding of the pathophysiologic mechanisms of fatigue in multiple sclerosis and its differential diagnosis, both of which are critical for individualized management.