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DOPTELET
Bleeding disorders
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Drug Name:

DOPTELET Rx

Generic Name and Formulations:
Avatrombopag 20mg; tabs.

Company:
Dova Pharmaceuticals

Therapeutic Use:

Indications for DOPTELET:

Thrombocytopenia in adults with chronic liver disease who are scheduled to undergo a procedure.

Adult:

Start treatment 10–13 days prior to a procedure. Should undergo procedure within 5–8 days after last dose. Take with food. Platelet count (<40 x 109/L): 60mg once daily for 5 days; (40–<50 x 109/L): 40mg once daily for 5 days.

Children:

Not established.

Warnings/Precautions:

Obtain platelet count prior to treatment and on day of procedure. Increased thrombotic risk with known risk factors (eg, Factor V Leiden, Prothrombin 20210A, Antithrombin deficiency, Protein C or S deficiency). Do not use to normalize platelet counts. Pregnancy; may cause fetal harm. Nursing mothers: not recommended (during and for ≥2 weeks after last dose).

Pharmacological Class:

Thrombopoietin receptor agonist.

Adverse Reactions:

Pyrexia, abdominal pain, nausea, headache, fatigue, peripheral edema; thrombotic/thromboembolic complications.

Generic Availability:

NO

How Supplied:

Tabs—10, 15

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