Colorectal disorders:

Indications for DIPENTUM:

Maintenance of remission in ulcerative colitis in patients intolerant of sulfasalazine.

Adult Dosage:

500mg twice a day with meals.

Children Dosage:

Not established.

DIPENTUM Warnings/Precautions:

Sulfasalazine allergy. Discontinue if acute intolerance syndrome is suspected. Conditions predisposing to myocarditis or pericarditis. Atopic dermatitis or eczema: may have more severe photosensitivity reactions. Nephrolithiasis. Ensure adequate hydration. Renal or hepatic impairment. Monitor renal function prior to and periodically during therapy. Elderly (monitor CBCs, platelets). Pregnancy. Nursing mothers: monitor infants.

DIPENTUM Classification:

Salicylate.

DIPENTUM Interactions:

Increased toxicity with nephrotoxic drugs (eg, NSAIDs). Increased risk for blood disorders, bone marrow failure, and associated complications with azathioprine or 6-mercaptopurine and/or other drugs known to cause myelotoxicity. May cause elevated test results when measuring urinary normetanephrine. Increased prothrombin time with warfarin; monitor and adjust dose.

Adverse Reactions:

Diarrhea, abdominal pain, rash, pruritus; acute intolerance syndrome (cramping, bloody diarrhea, fever, headache, rash), renal impairment, hypersensitivity reactions (discontinue if occur).

How Supplied:

Caps—100

Pricing for DIPENTUM

250mg capsule (Qty: 120)
Appx. price $1669
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