Indications for Naphazoline HCl:
For use as a topical ocular vasoconstrictor.
Adults and Children:
Instill 1 or 2 drops in the conjunctival sac(s) every 3–4hrs as needed.
Anatomically narrow angle or in narrow-angle glaucoma.
Hypertension. Cardiovascular abnormalities. Diabetes. Hyperthyroidism. Infection. Injury. Children (esp. infants): may result in CNS depression leading to coma and marked reduction in body temperature. Discontinue if no relief obtained within 48hrs of therapy, if irritation, blurring or redness persists or increases, or if symptoms of systemic absorption occur. Pregnancy (Cat.C). Nursing mothers.
Sympathomimetic (imidazoline derivative).
Concomitant maprotiline or tricyclic antidepressants may potentiate pressor effect. Severe hypertensive crisis possible with concomitant MAOIs.
Ocular (eg, mydriasis, increased redness, irritation, discomfort, blurring, punctate keratitis, lacrimation, increased intraocular pressure); systemic (eg, dizziness, headache, nausea, sweating, nervousness, drowsiness, weakness, hypertension, cardiac irregularities, hyperglycemia).