Hyperacidity, GERD, and ulcers:
Indications for NEXIUM 24HR:
Frequent heartburn (≥2 days/week). Not intended for immediate relief of heartburn (may take 1–4 days for full effect).
Swallow whole. Take before eating in the AM. ≥18yrs: 20mg once daily for 14 days; may repeat 14-day course every 4 months.
<18yrs: not recommended.
Heartburn >3 months. Frequent wheezing. Unexplained weight loss. Nausea/vomiting. Stomach pain. Reevaluate if condition continues or worsens after 14 days; >1 course of treatment every 4 months. Pregnancy. Nursing mothers.
Proton pump inhibitor.
May affect or be affected by blood-thinning agents (eg, warfarin, clopidogrel, cilostazol), antifungals, digoxin, diazepam, tacrolimus, mycophenolate mofetil, antiretrovirals, methotrexate.
Diarrhea, rash, joint pain; discontinue if occurs.
Caps—14, 28, 42