Smoking:

Indications for NICOTROL INHALER:

Adjunct in smoking cessation therapy.

Adult:

Each cartridge lasts about 20 minutes with frequent continuous puffing and provides nicotine equivalent to about 2 cigarettes. Individualize. Use at least 6 cartridges/day for 1st 3–6 weeks; max 16 cartridges/day for 1st 12 weeks, then reduce gradually over 12 more weeks.

Children:

Not recommended.

Contraindications:

Concurrent smoking or other nicotine products.

Warnings/Precautions:

Avoid immediately post-MI, in arrhythmias, or severe or worsening angina pectoris. Hypertension. Vasospastic or coronary heart disease. Hepatic or severe renal impairment. Hyperthyroidism. Pheochromocytoma. Diabetes. Peptic ulcer disease. Elderly. Low doses may be toxic to children and pets. Nasal Spray not recommended in chronic nasal disorders. Pregnancy (Cat.D), labor & delivery: not recommended (attempt nondrug treatment first). Nursing mothers.

See Also:

Interactions:

Nasal Spray antagonized by nasal vasoconstrictors. Smoking cessation potentiates theophylline, insulin, β-blockers, pentazocine, oxazepam, tricyclic antidepressants (eg, imipramine), caffeine, acetaminophen, adrenergic antagonists (eg, prazosin, labetalol), others. Smoking cessation antagonizes adrenergic agonists (eg, isoproterenol, phenylephrine), others.

Adverse Reactions:

Local irritation, GI upset, headache, dizziness, palpitations, hypertension.

How Supplied:

Inhaler 42 cartridges—1 (w. inhaler and case); Nasal Spray 10mL (200 sprays)—1 (w. metered spray pump)