ADD THIS DRUG TO MY LIST

Select the drug indication to add to your list

DYNACIN
Acne
Bacterial infections
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:

DYNACIN Rx

Generic Name and Formulations:
Minocycline (as HCl) 50mg, 75mg, 100mg; caps.

Company:
Par Pharmaceutical, Inc.

Therapeutic Use:

Indications for DYNACIN:

Adjunct in severe acne.

Adult:

Swallow whole. Take with fluids. 200mg once then 100mg every 12 hours; or 100–200mg once then 50mg four times daily.

Children:

≤8yrs: not recommended. Swallow whole. Take with fluids. >8yrs: 4mg/kg once then 2mg/kg (max 100mg) every 12 hours.

Warnings/Precautions:

Monitor blood, renal, and hepatic function in long-term use. Discontinue if skin erythema, DRESS syndrome, or superinfection develops. Overweight women. History of intracranial hypertension. Monitor for visual disturbances. Renal impairment; monitor BUN and creatinine. Hepatic impairment. Avoid sun or UV light. Pregnancy (Cat.D), nursing mothers: not recommended.

Pharmacological Class:

Tetracycline antibiotic.

Interactions:

Avoid concomitant penicillins, isotretinoin. Fatal renal toxicity with concomitant methoxyflurane. Caution with other hepatotoxic drugs. May need to reduce concomitant anticoagulant dose. Absorption reduced by antacids containing aluminum, calcium, magnesium and iron. May antagonize oral contraceptives. Concomitant ergots or derivatives; increased risk of ergotism. May interfere with fluorescence test.

Adverse Reactions:

Dizziness, GI upset, pruritus, increased BUN; teeth discoloration, delayed skeletal development, intracranial hypertension, C.difficile-associated diarrhea, photosensitivity, hepatotoxicity, skin/hypersensitivity reactions (may be severe).

How Supplied:

Tabs 50mg, 75mg—100, 1000; 100mg—50, 1000

Indications for DYNACIN:

Tetracycline-susceptible infections including respiratory, genitourinary, rickettsial, trachoma. Alternative for selected infections when penicillin is contraindicated. Anthrax due to B. anthracis.

Adult:

Swallow whole. Take with fluids. 200mg once then 100mg every 12 hours; or 100–200mg once then 50mg four times daily. Syphilis: treat for 10–15 days. Meningococcal carrier state: 100mg every 12 hours for 5 days. Mycobacterium marinum infection: 100mg every 12 hours for 6–8 weeks has been used. Uncomplicated urethral, endocervical, or rectal infection w. C.trachomatis or U. urealyticum: 100mg every 12 hours for at least 7 days. For men: Uncomplicated gonococcal infection (not urethritis or anorectal): 200mg once then 100mg every 12 hours for at least 4 days; urethritis: 100mg every 12 hours for 5 days.

Children:

≤8yrs: not recommended. Swallow whole. Take with fluids. >8yrs: 4mg/kg once then 2mg/kg (max 100mg) every 12 hours.

Warnings/Precautions:

Monitor blood, renal, and hepatic function in long-term use. Discontinue if skin erythema, DRESS syndrome, or superinfection develops. Overweight women. History of intracranial hypertension. Monitor for visual disturbances. Renal impairment; monitor BUN and creatinine. Hepatic impairment. Avoid sun or UV light. Pregnancy (Cat.D), nursing mothers: not recommended.

Pharmacological Class:

Tetracycline antibiotic.

Interactions:

Avoid concomitant penicillins, isotretinoin. Fatal renal toxicity with concomitant methoxyflurane. Caution with other hepatotoxic drugs. May need to reduce concomitant anticoagulant dose. Absorption reduced by antacids containing aluminum, calcium, magnesium and iron. May antagonize oral contraceptives. Concomitant ergots or derivatives; increased risk of ergotism. May interfere with fluorescence test.

Adverse Reactions:

Dizziness, GI upset, pruritus, increased BUN; teeth discoloration, delayed skeletal development, intracranial hypertension, C.difficile-associated diarrhea, photosensitivity, hepatotoxicity, skin/hypersensitivity reactions (may be severe).

How Supplied:

Tabs 50mg, 75mg—100, 1000; 100mg—50, 1000

Sign Up for Free e-newsletters



CME Focus