ECTRIMS 2015

Vitamin D Beneficial for Cognition, Disease Activity in Multiple Sclerosis

Vitamin D Beneficial for Cognition, Disease Activity in Multiple Sclerosis

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Higher levels of vitamin D were associated with decreased disease activity in people with RRMS.

Teriflunomide Slows Brain Atrophy in Relapsing Multiple Sclerosis

Teriflunomide Slows Brain Atrophy in Relapsing Multiple Sclerosis

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Significant differences vs. placebo were maintained over 24 months.

Rapid Assessment Tool Useful for Multiple Sclerosis Evaluation

Rapid Assessment Tool Useful for Multiple Sclerosis Evaluation

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The test can be completed in about one minute and is free to use for clinicians and researchers.

Expression of DICAM on TH17 Lymphocytes Documented in Neuroinflammation

Expression of DICAM on TH17 Lymphocytes Documented in Neuroinflammation

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DICAM was strongly linked with expression of ROR-γ, IL-23R, IL-17, IL-22, GM-CSF, and GZMB expression in human CD4+ lymphocytes.

NEDA-4 More Accurate Measure of Activity in Relapsing Multiple Sclerosis

NEDA-4 More Accurate Measure of Activity in Relapsing Multiple Sclerosis

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The additional measure of brain volume loss results in a more comprehensive evaluation of disease activity in RRMS.

Comorbid MS, Major Depressive Disorder Linked to Brain Volume Loss

Comorbid MS, Major Depressive Disorder Linked to Brain Volume Loss

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Changes to brain structure indicate possible underlying connection to idiopathic major depressive disorder.

Online Cognitive Behavioral Therapy Reduces Fatigue in Multiple Sclerosis

Online Cognitive Behavioral Therapy Reduces Fatigue in Multiple Sclerosis

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Participants also reported a reduction in anxiety and subjective cognitive impairment.

Smoking Cessation Slows Brain Volume Loss in Multiple Sclerosis

Smoking Cessation Slows Brain Volume Loss in Multiple Sclerosis

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Compared to those who continued smoking, those who stopped experienced a significant decline in the rate of brain volume loss.

Grey, White Matter Ratio and Disability in Relapsing-Remitting Multiple Sclerosis

Grey, White Matter Ratio and Disability in Relapsing-Remitting Multiple Sclerosis

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The ratio was also predictive of conversion to secondary-progressive MS.

Neurofilament Light Chain Level Predicts Brain Volume Loss at First Sign of MS

Neurofilament Light Chain Level Predicts Brain Volume Loss at First Sign of MS

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CSF NfL levels were predictive of brain volume loss at first sign of MS and follow-up.

Spinal Cord Grey Matter Atrophy Has Greatest Clinical Impact in MS

Spinal Cord Grey Matter Atrophy Has Greatest Clinical Impact in MS

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Spinal cord gray matter atrophy was found to be most relevant compared to other conventional MRI metrics.

Cervical Cord Atrophy, Lesions Predict Disability in Multiple Sclerosis

Cervical Cord Atrophy, Lesions Predict Disability in Multiple Sclerosis

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Compared to RRMS, progressive MS had greater cord atrophy and lesions.

Similar Effects Seen for Fingolimod, Placebo in Primary Progressive Multiple Sclerosis

Similar Effects Seen for Fingolimod, Placebo in Primary Progressive Multiple Sclerosis

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No significant treatment effect on disease progression or brain or cervical spinal atrophy was observed.

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