Epilepsy and Seizures

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Vagus Nerve Stimulation in Pediatric Epilepsy: Weighing the Risks and Benefits

Vagus Nerve Stimulation in Pediatric Epilepsy: Weighing the Risks and Benefits

Studies that have evaluated the use of VNS in children, including those as young as 6 months old, and have generally concluded that it is well tolerated and improves quality of life.

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Early Treatment Failure More Likely With Carbamazepine vs Lamotrigine in Epilepsy

Early Treatment Failure More Likely With Carbamazepine vs Lamotrigine in Epilepsy

The results of this review are applicable primarily to persons with focal onset seizures, with 88% of included participants experiencing this type of seizure at baseline.

High Anxiety Symptoms Prevalent in Epilepsy, Mesial Temporal Sclerosis

High Anxiety Symptoms Prevalent in Epilepsy, Mesial Temporal Sclerosis

Investigators assessed demographic and epilepsy-specific factors independently associated with anxiety, including lesions and seizure focus localization.

Treatment of New-Onset Epilepsy: AAN, AES Update Practice Guidelines

Treatment of New-Onset Epilepsy: AAN, AES Update Practice Guidelines

An expert subcommittee was formed consisting of members of the AAN and AES to update the 2004 evidence-based guidelines on epilepsy treatment with AEDs.

New Formulation of Status Epilepticus Treatment To Be Reviewed

New Formulation of Status Epilepticus Treatment To Be Reviewed

The NDA for IM/IV Captisol-Enabled Fosphenytoin has been accepted for review and given a Prescription Drug Fee User Act date, by the FDA.

Modifiable Midlife Risk Factors Linked to Late-Onset Epilepsy

Modifiable Midlife Risk Factors Linked to Late-Onset Epilepsy

Potentially modifiable risk factors in midlife are associated with the risk of developing late-onset epilepsy.

Disease-Specific ICD Code Helps Identify Infantile Spasms in Claims Data

Disease-Specific ICD Code Helps Identify Infantile Spasms in Claims Data

Claims data spanning 4 years were obtained from a pediatric accountable care organization.

Evidence for Clobazam Monotherapy Use in Focal, Generalized Seizures Reviewed

Evidence for Clobazam Monotherapy Use in Focal, Generalized Seizures Reviewed

The safety and efficacy of clobazam monotherapy in patients with new-onset focal or generalized seizures was investigated in a new Cochrane systematic review.

Weight-Adjusted Lacosamide Effective for Benzodiazepine-Resistant Status Epilepticus

Weight-Adjusted Lacosamide Effective for Benzodiazepine-Resistant Status Epilepticus

The efficacy was reported to be significantly higher in patients who had taken benzodiazepines.

Cardiac Pathology in SUDEP Compared With Sudden Arrhythmic or Traumatic Deaths

Cardiac Pathology in SUDEP Compared With Sudden Arrhythmic or Traumatic Deaths

Causes of death in patients with epilepsy were assessed to determine the presence of cardiac pathology.

Vigadrone Available for Refractory Complex Partial Seizures, Infantile Spasms

Vigadrone Available for Refractory Complex Partial Seizures, Infantile Spasms

The FDA has approved an abbreviated New Drug Application for Vigadrone, the generic alternative to Sabril powder for oral solution.

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