Epilepsy and Seizures

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Strategies for Reducing Cognitive Deficits in Pediatric Epilepsy

Strategies for Reducing Cognitive Deficits in Pediatric Epilepsy

In the past, many epilepsy providers have focused solely on seizure control as a way to improve developmental outcomes and HRQOL; however, we now know that the most effective treatment for pediatric epilepsy is comprehensive.

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First Generic Version of Sabril Tablets Gets FDA Approval

First Generic Version of Sabril Tablets Gets FDA Approval

As treatment with vigabatrin may be associated with permanent vision loss, the generic tablets are also part of a single shared-system Risk Evaluation and Mitigation Strategy (REMS) program to ensure the product is used safely.

Psychotherapy May Reduce Frequency of Nonepileptic Seizures

Psychotherapy May Reduce Frequency of Nonepileptic Seizures

Adherence to psychotherapy is associated with improved outcomes in individuals with psychogenic nonepileptic seizures.

Seizure Monitoring Smartwatch Cleared for Use in Children

Seizure Monitoring Smartwatch Cleared for Use in Children

The Food and Drug Administration has granted 501(k) clearance to the Embrace watch for use in epilepsy patients aged ≥6 years. The smartwatch identifies generalized tonic-clonic seizures and alerts caregivers.

Researchers ID Factors Predictive of Naming Decline After Epilepsy Surgery

Researchers ID Factors Predictive of Naming Decline After Epilepsy Surgery

The use of externally validated nomograms in 2 easy-to-use formats can help physicians assess the probability of naming decline in patients considering epilepsy surgery for treatment of pharmacoresistant temporal lobe epilepsy.

CBD Superior to Placebo, Similar to AEDs for Managing Epilepsy Syndromes

CBD Superior to Placebo, Similar to AEDs for Managing Epilepsy Syndromes

Cannabinoids appeared more effective than placebo and similarly efficacious as other antiepileptic drugs for managing pediatric patients with Dravet syndrome and Lennox-Gastaut syndrome as well as adults with epilepsy.

Prenatal Valproate Exposure Linked to Increased ADHD Risk

Prenatal Valproate Exposure Linked to Increased ADHD Risk

Use of the antiepileptic drug (AED) valproate during pregnancy is associated with an increased risk for attention-deficit/hyperactivity disorder (ADHD) among offspring.

Postresection Monitoring May Provide Further Insights on Epileptogenic Zone Following Multistage Epilepsy Surgery

Postresection Monitoring May Provide Further Insights on Epileptogenic Zone Following Multistage Epilepsy Surgery

Investigators found that it may be prudent to continue postoperative invasive monitoring in children who have had surgical resection of epileptic lesions.

Aggressive, Prolonged Treatment for Refractory Status Epilepticus May Be Justified With Good Neurologic Prognosis

Aggressive, Prolonged Treatment for Refractory Status Epilepticus May Be Justified With Good Neurologic Prognosis

Aggressive and prolonged treatment of refractory status epilepticus may be justified in patients with cardiac arrest with favorable multimodal prognostic indicators.

Multivariable Clinical Trait Model Predicts Childhood Epilepsy Risk

Multivariable Clinical Trait Model Predicts Childhood Epilepsy Risk

Researchers sought to develop a prediction model that determines the risk for childhood epilepsy and included clinical characteristic variables such as sex, medical history, age of first seizure, and event description, along with electroencephalogram readings.

Heart Rate, Movement Detect Nocturnal Seizures in Epilepsy

Heart Rate, Movement Detect Nocturnal Seizures in Epilepsy

Investigators examined whether a bracelet capable of measuring heart rate and movement would be beneficial for detecting nocturnal seizures in patients with epilepsy.

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