Investigators evaluated seizure stimulation parameters, electroclinical data, semiology, and anatomical localization in spontaneous and stimulated seizures.
Investigators analyzed the NBEA gene to determine whether or not it could be a biomarker for early childhood epilepsy.
Myoclonic-Atonic Seizures and Lennox-Gastaut Syndrome Present With Overlapping Features, Difficulty in DiagnosisDecember 11, 2018
Patients with a higher number of Lennox-Gastaut syndrome traits had a greater likelihood of ongoing seizures, and each additionally observed Lennox-Gastaut syndrome trait was associated with half the likelihood of achieving seizure freedom.
Compared with nonmotor seizures, there was a significant difference with basal ganglia and thalamus coactivation in terms of seizures with elementary motor signs and automatisms.
Lorcaserin may reduce seizure frequency in patients with Dravet syndrome and severe childhood-onset epilepsies.
The study utilized the Vaccine Safety Datalink and included children who received the first dose of a measles-containing vaccine between 12 and 23 months old during the study period of January 1, 2003 to September 20, 2015.
Investigators assessed the frequency of bilateral independent periodic discharges in patients experiencing electrographic seizures and their effect on patient mortality and clinical outcomes.
Eslicarbazepine acetate is well tolerated and may be effective for treating patients with post-stroke epilepsy.
Adjunctive brivaracetam may provide long term effectiveness in adults who have not seen optimal results with other common treatments.
Bioequivalent generic formulations of 2 antiepileptic medications were comparable to brand name treatments for new-onset epilepsy.
Researchers aimed to identify risk factors associated with a psychiatric event following a first prescription for levetiracetam.
Children with Dravet syndrome receiving fenfluramine experienced improvements in emotional regulation, behavioral regulation, and planning and organization abilities.
Patients taking an active treatment regimen consisting of SSRIs, TCAs, or antipsychotic medications are less likely to experience a seizure in the epilepsy monitoring unit.
The classic ketogenic diet may not have a significant impact on preventing shttp://cms.haymarketmedia.com/Images/find.gifeizure occurrence in patients with infantile spasms of unknown etiology.
Individual treatment-emergent adverse events (TEAE) did not increase with higher modal daily dose of eslicarbazepine acetate in pediatric patients with focal seizures.
Perampanel at a median maximum dose of 6 mg (1 to 20 mg) is associated with good long-term treatment retention and sustained efficacy.
Investigators aimed to determine whether utilization of enzyme-inducing antiepileptic drugs increases vitamin D requirements.
Low total benzodiazepine dosing is linked to longer intensive care unit stays and seizure duration in children.
An investigational transdermal cannabidiol gel was well-tolerated and consistently effective for adults with focal epilepsy.
Patients at high risk for SUDEP may shift to a lower risk group over time.
Tolerance to cannabidiol may exist, potentially limiting its efficacy as an antiseizure therapy in the long-term management of epilepsy.
Patients with focal epilepsy and comorbid migraine may have greater depressive symptoms compared with individuals without the comorbidity.
Investigators examined whether a reduction in titration rates utilized in earlier trials would reduce the incidence of DRESS in patients taking cenobamate.
Safety and efficacy were examined in adults aged 60 compared with adults younger than 60.
Antiepileptic drugs are more likely to be tolerated by patients who have not experienced adverse drug reactions to previous antiepileptic drugs.
Teen patients with epilepsy experience high levels of depressive symptoms, with 13% requiring behavioral health interventions.
Investigators observed that in pregnant women with epilepsy, the body begins to rapidly metabolize lamotrigine and levetiracetam at week 16 causing a fluctuating pattern of serum drug concentration.
Midazolam nasal spray, a novel benzodiazepine formulation, may be a safe, long-term treatment option for acute seizure episodes.
Individuals with epilepsy who receive an early genetic diagnosis may benefit from more precise medical treatment and accurate counseling.
In the retrospective study, the primary reason for initiating perampanel was poor seizure control.
Neurology Advisor Articles
- Surgical, Nonsurgical Treatments for Chronic Migraine: Evidence and Relevancy
- Neurofilament Light Biomarkers Identify Alzheimer Disease Risk in Down Syndrome
- Myoclonic-Atonic Seizures and Lennox-Gastaut Syndrome Present With Overlapping Features, Difficulty in Diagnosis
- Tap Water in Neti Pot Linked to Brain Infection, Death From Balamuthia mandrillaris
- Rituximab Effects in Neuromyelitis Optica Spectrum Disorders
- Study Identifies Early-Onset Motor Behaviors in DES-Triggered Seizures
- Autoimmune Diseases Increase Hippocampal Sclerosis Risk in Nonagenarians
- Smaller Heads Related to Opioid-Related Neonatal Abstinence Syndrome
- Hearing Loss in Older Adults Linked to Depression, Dementia Among Other Comorbidities
- Bumetanide May Benefit Children With Autism Spectrum Disorder