Epilepsy
Add-On Cannabidiol for Treatment-Resistant Drop Seizures in Lennox-Gastaut Syndrome
April 19, 2018Cannabidiol may be effective as add-on treatment for drop seizures associated with Lennox-Gastaut syndrome.
Afinitor Disperz Approved to Treat TSC-Associated Partial-Onset Seizures
April 18, 2018The FDA has approved Afinitor Disperz for the adjunctive treatment of patients aged ≥2 years with TSC-associated partial-onset seizures.
Increased Risk of Unnatural Death in People With Epilepsy
April 18, 2018The risk of unnatural death is increased among people with epilepsy.
Cannabidiol Safe, Well Tolerated in Children With Dravet Syndrome
April 16, 2018Because of the small size of the study sample, the findings may be limited to this patient population and may be hard to generalize across all pediatric patients with Dravet syndrome.
EEG Changes in Pediatric BECTS Promoted by Treatment With Levetiracetam, Sulthiame
April 13, 2018The small sample size included in the study precludes the ability to make generalized statements about electroencephalogram pattern characteristics in the entire pediatric patient population with BECTS.
Early-Life Epilepsy Should Be Urgently Treated With EBM
April 13, 2018Best diagnostics and evidence-based treatments should be used from the start of the disease.
Educational Attainment Down With In Utero Exposure to AEDs
April 09, 2018Exposure to sodium valproate or a combination of antiepileptic drugs in utero is associated with worse attainment on national educational tests.
Fycompa sNDA Submitted for Pediatric Seizure Indications
April 04, 2018The proposed pediatric indications are based on a 2018 Draft Guidance that supports extrapolating efficacy data of approved drugs to treat POS in adults to pediatric patients aged ≥4 years.
Code Stroke System Reduces Post-Stroke Epilepsy Risk in Older Adults
April 02, 2018The adjusted analysis also demonstrated that the code stroke system was associated with a decreased risk for post-stroke epilepsy within 5 years of stroke.
Epilepsy Associated With Greater Risk for Serious Transportation Accidents
March 27, 2018The registers used in this study did not collect information on whether individuals with epilepsy were actually responsible for the transportation accidents.
A Convenient Truth: The Problem With Seizure Under-Reporting and How to Fix It
March 23, 2018Before we begin to rely more heavily on technology for seizure detection, clinician-patient trust needs to improve.
Cannabinoids May Be Effective as Adjunctive Treatment for Refractory Epilepsy
March 23, 2018Pharmaceutical-grade CBD used as adjunctive therapy in patients with pediatric-onset drug-resistant epilepsy may reduce the frequency of seizures.
Older Epilepsy Patients More Likely to Experience AED, Non-AED Drug Interaction
March 16, 2018The findings are limited to the 50 most-prescribed non-epilepsy drugs assessed in this Medicare population and may not generalize to non-Medicare beneficiaries who receive other non-epilepsy drugs.
More Evidence Supports Benefits of Cannabidiol for Treatment-Resistant Epilepsy
March 13, 2018Cannabinoids are effective as an adjunctive treatment for reducing seizure frequency in pediatric-onset treatment-resistant epilepsy.
Predicting Seizure Risk Following Ischemic Stroke With SeLECT Score
March 12, 2018Investigators sought to validate a tool to identify post-stroke seizure risk.
Behavioral Interventions May Have Some Benefit in Refractory Epilepsy
March 09, 2018Participants in the progressive muscle relaxation group reported greater reductions in stress vs those randomized to the focused-attention activity.
Vitamin D Supplement May Benefit Bone Health in Epilepsy
March 06, 2018Five studies demonstrated a significant improvement in serum 25-hydroxyvitamin D from baseline to post-treatment vitamin D supplementation in patients with epilepsy.
Levetiracetam Associated With Less Monotherapy Failure in Infantile Seizures
March 02, 2018The study findings are particularly relevant given the current mismatch between clinical practice and regulatory approval of levetiracetam in infantile seizures.
Consensus Statement: Defining Pediatric Status Epilepticus Syndromes
March 01, 2018The investigators hope that the consensus statement helps resolve several clinical questions in cases of pediatric new onset status epilepticus syndromes.
Exposure to Valproate During Pregnancy May Have Effect on Offspring's School Performance
March 01, 2018School performance is lower in children with prenatal exposure to valproate.
Seizure Frequency May Lessen With Stress Reduction
February 27, 2018Participants recorded daily mood and stress ratings plus seizure counts using an electronic diary and medication adjustments were not allowed.
Influenza vaccine not associated with increased risk of epilepsy in children
February 15, 2018No increased risk of incident epilepsy was seen among children who received influenza vaccination during the 2009-2010 influenza season in Norway.
Chronic Traumatic Encephalopathy Uncommon in Treatment-Refractory Epilepsy
February 13, 2018While epilepsy-related head trauma was common, 9 of 10 patients displayed no evidence of CTE.
FDA Approves Smart Watch for Epilepsy Management
February 13, 2018The FDA has cleared the Embrace smart watch for managing epilepsy.
Cannabidiol Reduces Drop Seizures in Lennox-Gastaut Syndrome
February 02, 2018Add-on cannabidiol is associated with reduced monthy drop seizure frequency in patients with Lennox-Gastaut sydrome associated drop seizures.
Focal Epilepsy Linked to Increased Risk for Mood Disorders
January 31, 2018Clinicians should evaluate their patients, especially patients with focal epilepsy, for mood disorders.
High Doses of Topiramate for Epilepsy in Pregnancy Increase Risks for Oral Clefts in Offspring
January 23, 2018Women receiving topiramate for epilepsy were exposed to high cumulative doses, increasing the risk for oral clefts in offspring.
Seizure Control Diminishes With Subsequent Antiepileptic Drug Therapy
January 19, 2018Patients with tough-to-treat seizures may require nonpharmacologic treatment such as resective surgery.
More Than One-Third of New Cases of Epilepsy Are Treatment Refractory
January 10, 2018Over one-third of patients with newly diagnosed epilepsy do not respond to antiepileptic drug treatment.
Treating Levetiracetam-Induced Behavioral Effects With Vitamin B6
January 09, 2018Vitamin B6 was found to effectively treat the behavioral adverse effects seen with levetiracetam.
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- CSF Chitinase-3-Like Protein 1 Level Not Predictor of RIS Conversion
- MS Disease-Modifying Therapy May Safely Be Discontinued in Older Patients
- Add-On Cannabidiol for Treatment-Resistant Drop Seizures in Lennox-Gastaut Syndrome
- Post-Recanalization Stroke Score More Effective Than Baseline Score for Predicting 3-Month Outcome
- Psychosis Could Be a Potential Side Effect of Steroid Treatment in Kids