Cannabidiol may be effective as add-on treatment for drop seizures associated with Lennox-Gastaut syndrome.
The FDA has approved Afinitor Disperz for the adjunctive treatment of patients aged ≥2 years with TSC-associated partial-onset seizures.
The risk of unnatural death is increased among people with epilepsy.
Because of the small size of the study sample, the findings may be limited to this patient population and may be hard to generalize across all pediatric patients with Dravet syndrome.
The small sample size included in the study precludes the ability to make generalized statements about electroencephalogram pattern characteristics in the entire pediatric patient population with BECTS.
Best diagnostics and evidence-based treatments should be used from the start of the disease.
Exposure to sodium valproate or a combination of antiepileptic drugs in utero is associated with worse attainment on national educational tests.
The proposed pediatric indications are based on a 2018 Draft Guidance that supports extrapolating efficacy data of approved drugs to treat POS in adults to pediatric patients aged ≥4 years.
The adjusted analysis also demonstrated that the code stroke system was associated with a decreased risk for post-stroke epilepsy within 5 years of stroke.
The registers used in this study did not collect information on whether individuals with epilepsy were actually responsible for the transportation accidents.
Before we begin to rely more heavily on technology for seizure detection, clinician-patient trust needs to improve.
Pharmaceutical-grade CBD used as adjunctive therapy in patients with pediatric-onset drug-resistant epilepsy may reduce the frequency of seizures.
The findings are limited to the 50 most-prescribed non-epilepsy drugs assessed in this Medicare population and may not generalize to non-Medicare beneficiaries who receive other non-epilepsy drugs.
Cannabinoids are effective as an adjunctive treatment for reducing seizure frequency in pediatric-onset treatment-resistant epilepsy.
Investigators sought to validate a tool to identify post-stroke seizure risk.
Participants in the progressive muscle relaxation group reported greater reductions in stress vs those randomized to the focused-attention activity.
Five studies demonstrated a significant improvement in serum 25-hydroxyvitamin D from baseline to post-treatment vitamin D supplementation in patients with epilepsy.
The study findings are particularly relevant given the current mismatch between clinical practice and regulatory approval of levetiracetam in infantile seizures.
The investigators hope that the consensus statement helps resolve several clinical questions in cases of pediatric new onset status epilepticus syndromes.
School performance is lower in children with prenatal exposure to valproate.
Participants recorded daily mood and stress ratings plus seizure counts using an electronic diary and medication adjustments were not allowed.
No increased risk of incident epilepsy was seen among children who received influenza vaccination during the 2009-2010 influenza season in Norway.
While epilepsy-related head trauma was common, 9 of 10 patients displayed no evidence of CTE.
The FDA has cleared the Embrace smart watch for managing epilepsy.
Add-on cannabidiol is associated with reduced monthy drop seizure frequency in patients with Lennox-Gastaut sydrome associated drop seizures.
Clinicians should evaluate their patients, especially patients with focal epilepsy, for mood disorders.
Women receiving topiramate for epilepsy were exposed to high cumulative doses, increasing the risk for oral clefts in offspring.
Patients with tough-to-treat seizures may require nonpharmacologic treatment such as resective surgery.
Over one-third of patients with newly diagnosed epilepsy do not respond to antiepileptic drug treatment.
Vitamin B6 was found to effectively treat the behavioral adverse effects seen with levetiracetam.
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