Epilepsy
Psychotherapy May Reduce Frequency of Nonepileptic Seizures
January 15, 2019Adherence to psychotherapy is associated with improved outcomes in individuals with psychogenic nonepileptic seizures.
Seizure Monitoring Smartwatch Cleared for Use in Children
January 14, 2019The Food and Drug Administration has granted 501(k) clearance to the Embrace watch for use in epilepsy patients aged ≥6 years. The smartwatch identifies generalized tonic-clonic seizures and alerts caregivers.
Researchers ID Factors Predictive of Naming Decline After Epilepsy Surgery
January 11, 2019The use of externally validated nomograms in 2 easy-to-use formats can help physicians assess the probability of naming decline in patients considering epilepsy surgery for treatment of pharmacoresistant temporal lobe epilepsy.
CBD Superior to Placebo, Similar to AEDs for Managing Epilepsy Syndromes
January 10, 2019Cannabinoids appeared more effective than placebo and similarly efficacious as other antiepileptic drugs for managing pediatric patients with Dravet syndrome and Lennox-Gastaut syndrome as well as adults with epilepsy.
Prenatal Valproate Exposure Linked to Increased ADHD Risk
January 10, 2019Use of the antiepileptic drug (AED) valproate during pregnancy is associated with an increased risk for attention-deficit/hyperactivity disorder (ADHD) among offspring.
Postresection Monitoring May Provide Further Insights on Epileptogenic Zone Following Multistage Epilepsy Surgery
January 09, 2019Investigators found that it may be prudent to continue postoperative invasive monitoring in children who have had surgical resection of epileptic lesions.
Aggressive, Prolonged Treatment for Refractory Status Epilepticus May Be Justified With Good Neurologic Prognosis
January 08, 2019Aggressive and prolonged treatment of refractory status epilepticus may be justified in patients with cardiac arrest with favorable multimodal prognostic indicators.
Multivariable Clinical Trait Model Predicts Childhood Epilepsy Risk
January 07, 2019Researchers sought to develop a prediction model that determines the risk for childhood epilepsy and included clinical characteristic variables such as sex, medical history, age of first seizure, and event description, along with electroencephalogram readings.
Heart Rate, Movement Detect Nocturnal Seizures in Epilepsy
January 01, 2019Investigators examined whether a bracelet capable of measuring heart rate and movement would be beneficial for detecting nocturnal seizures in patients with epilepsy.
Nocturnal Seizures With Convulsions Linked to SUDEP
December 31, 2018Investigators sought to predict the incidence of SUDEP in people with intellectual disabilities in residential care settings and to determine its relationship with nocturnal seizures and nocturnal supervision.
Acetaminophen Is Safe, May Be Effective to Reduce Febrile Seizure Recurrence
December 27, 2018Investigators sought to determine whether rectal acetaminophen reduces rates of second febrile seizure in children during the same febrile illness when given rectally shortly after initial seizure.
Strategies for Reducing Cognitive Deficits in Pediatric Epilepsy
December 20, 2018In the past, many epilepsy providers have focused solely on seizure control as a way to improve developmental outcomes and HRQOL; however, we now know that the most effective treatment for pediatric epilepsy is comprehensive.
Oxtellar XR Gains Monotherapy Indication for Partial-Onset Seizures
December 19, 2018The FDA has approved the supplemental New Drug Application for Oxtellar XR to include monotherapy use for the treatment of partial-onset seizures patients aged ≥6 years.
Volume Perfusion CT Helps Differentiate Ictal Stroke Mimics, but Not Postictal, From Acute Ischemic Stroke
December 18, 2018Patients were initially misjudged to have presented with an acute stroke instead of an epileptic seizure.
Unplanned Pregnancy in Women With Epilepsy Increases Risk for Spontaneous Fetal Loss
December 17, 2018Investigators assessed the effect of unplanned vs planned pregnancies in this patient population on the risk for SFL.
Epilepsy, Sleep Apnea, and SUDEP: A Closer Look
December 17, 2018The comorbid presence of central apnea has been identified by multiple researchers as predictive of SUDEP.
Study Identifies Early-Onset Motor Behaviors in DES-Triggered Seizures
December 14, 2018Investigators evaluated seizure stimulation parameters, electroclinical data, semiology, and anatomical localization in spontaneous and stimulated seizures.
NBEA Gene Associated With Neurodevelopmental Delay, Childhood Epilepsy
December 12, 2018Investigators analyzed the NBEA gene to determine whether or not it could be a biomarker for early childhood epilepsy.
Myoclonic-Atonic Seizures and Lennox-Gastaut Syndrome Present With Overlapping Features, Difficulty in Diagnosis
December 11, 2018Patients with a higher number of Lennox-Gastaut syndrome traits had a greater likelihood of ongoing seizures, and each additionally observed Lennox-Gastaut syndrome trait was associated with half the likelihood of achieving seizure freedom.
SISCOM Hyperperfusion Identifies Epilepsy Lateralization
December 11, 2018Compared with nonmotor seizures, there was a significant difference with basal ganglia and thalamus coactivation in terms of seizures with elementary motor signs and automatisms.
Lorcaserin May Reduce Motor Seizures in Pediatric Treatment-Resistant Epilepsy
December 06, 2018Lorcaserin may reduce seizure frequency in patients with Dravet syndrome and severe childhood-onset epilepsies.
Does Gestational Age at Birth Affect Seizure Risk After Measles Vaccine Administration?
December 06, 2018The study utilized the Vaccine Safety Datalink and included children who received the first dose of a measles-containing vaccine between 12 and 23 months old during the study period of January 1, 2003 to September 20, 2015.
Bilateral Independent Periodic Discharges and Poor Seizure Outcomes
December 05, 2018Investigators assessed the frequency of bilateral independent periodic discharges in patients experiencing electrographic seizures and their effect on patient mortality and clinical outcomes.
Eslicarbazepine Acetate Well Tolerated, Effective in Post-Stroke Epilepsy
December 04, 2018Eslicarbazepine acetate is well tolerated and may be effective for treating patients with post-stroke epilepsy.
Long-Term Effectiveness of Adjunctive Brivaracetam For Previously Treated Focal Seizures
December 04, 2018Adjunctive brivaracetam may provide long term effectiveness in adults who have not seen optimal results with other common treatments.
Generic Lamotrigine, Levetiracetam Formulations Comparable to Brand Name AEDs
December 04, 2018Bioequivalent generic formulations of 2 antiepileptic medications were comparable to brand name treatments for new-onset epilepsy.
Psychiatric Adverse Effects from Levetiracetam Linked to Certain Factors
December 04, 2018Researchers aimed to identify risk factors associated with a psychiatric event following a first prescription for levetiracetam.
Fenfluramine Improves Emotion and Behavior Regulation in Pediatric Dravet Syndrome
December 04, 2018Children with Dravet syndrome receiving fenfluramine experienced improvements in emotional regulation, behavioral regulation, and planning and organization abilities.
SSRIs, TCAs, Antipsychotics Decrease Seizure Frequency in the Epilepsy Monitoring Unit
December 03, 2018Patients taking an active treatment regimen consisting of SSRIs, TCAs, or antipsychotic medications are less likely to experience a seizure in the epilepsy monitoring unit.
Does the Ketogenic Diet Prevent Relapse in Infantile Spasms?
December 03, 2018The classic ketogenic diet may not have a significant impact on preventing shttp://cms.haymarketmedia.com/Images/find.gifeizure occurrence in patients with infantile spasms of unknown etiology.
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