There are currently no treatments available for frontotemporal dementia.
Investigators sought to identify genetic factors that may contribute to the risk for neurodegenerative diseases, such as amyotrophic lateral sclerosis and frontotemporal dementia.
The investigators hope that the findings from the study help raise awareness of frontotemporal dementia in geriatric patients.
Using a transcranial magnetic stimulation approach might make it easier to distinguish Alzheimer's disease from frontotemporal dementia.
Neuroimaging and if necessary, genetic testing, can help to confirm an FTD diagnosis.
Eating abnormalities in frontotemporal dementia result from a network of brain regions, rather than 1or 2 specific structures.
Addressing proteasome dysfunction may help prevent accumulation of the toxic protein.
A gene mutation behind a large amount of ALS and FTD cases may disrupt nuclear transport, destroying neurons.
The mouse model will allow researchers to effectively test therapeutic compounds.
The results support the "cognitive reserve" theory that greater mental activity promotes brain connectivity.
C9orf72 hypermethylation helps protect the brain against damage in ALS and frontotemporal degeneration.
Alzheimer's patients had 1.4 times higher concentrations of IAPP than non-Alzheimer's patients in temporal cortex.
The highest dose of intranasal oxytocin seemed to produce the best response.
Neurology Advisor Articles
- Higher Levels of Cholesterol May Protect Men From Parkinson Disease
- Early Clinical Traits of Multiple Sclerosis Prodrome Identified
- Chronic Pain May Be Contributor to Suicide
- FDA Approves Tiglutik for the Treatment of Amyotrophic Lateral Sclerosis
- Ajovy Injection Approved for Migraine Prevention in Adults
- 5 Key Findings Presented at 2018 Parkinson Disease Conference
- Parkinson Disease and the Gut: Treatment Potential Abounds
- Managing Comorbid Migraine and Mood Disorders: A Synergistic Approach
- Stroke-Code Patients With Low NIHSS Score, No Acute Imaging Findings Often Misdiagnosed
- Ethical Challenges of Nusinersen: Considerations When Counseling on Treatment
- Brivaracetam Effective for Reducing Seizures in Patients with Epileptic Encephalopathies
- Familial Hemiplegic Migraine Attacks May Be Associated With Cortical Swelling
- Natalizumab Improves Cognitive Function in Multiple Sclerosis
- Fremanezumab May Have Long-Term Efficacy as a Prophylactic for Chronic Migraine
- Propofol May Decrease Delay in Neurocognitive Recovery