General Neurology News Archive
Intellectual engagement is associated with level of cognitive performance in later life but does not influence the trajectory of age-related decline in cognitive performance.
Investigators sought to determine how prevalent and severe intractable nausea, vomiting, or hiccups are in patients with AQP4-IgG-positive NMOSD.
The use of tap water in a nasal-flushing Neti pot likely led to a Seattle woman's death from a Balamuthia mandrillaris brain infection.
Investigators sought to determine whether rituximab would have long-term effects on total and specific immunoglobulins in patients with neuromyelitis optica spectrum disorders.
Investigators examined neuropsychological outcomes of children who survived pediatric cardiac arrest.
The number of cases of acute flaccid myelitis in the United States this year appears to have peaked and is expected to decline for the remainder of 2018.
A case description can reliably define patients with acute flaccid myelitis.
A recent study supports the use of the long exercise test to diagnose periodic paralysis.
Investigators reviewed a case study of 2 brothers with retinal vasculopathy with cerebral leukoencephalopathy to learn more about this rare disease.
Clinicians and public health practitioners should advise expectant parents on ways to prevent childhood lead exposure.
In-home services such as help with household chores and caregiver respite will be available to seniors with private Medicare Advantage plans in more than 20 states next year.
A task force to investigate a rising number of cases of a rare polio-like disease among children in the United States has been created by the US Centers for Disease Control and Prevention.
The antiviral agent fluoxetine is well tolerated but is not effective for patients with proven or presumptive enterovirus D68-associated acute flaccid myelitis.
The announcement comes in the wake of results from the 2018 National Youth Tobacco Survey which showed a 78% increase in current e-cigarette use among high school students from 2017 to 2018.
The authors found that the compounds known as phenylindanes inhibited the aggregation of the amyloidgenic proteins beta-amyloid and tau.
This guidance, updated for the first time since 2008, provides evidence-based recommendations for children (ages 3-17) and adults.
The new software enables patients to fine-tune the power level and modify programs that were pre-programmed by their clinician to control pain.
Abstaining from cannabis is associated with improvements in memory and verbal learning in adolescents and young adults.
Higher serum cortisol level is associated with lower brain volumes and impaired memory in asymptomatic younger to middle-aged adults.
Cases of a polio-like condition that mainly affects children continue to rise this year in the United States, health officials say.
The 23andMe Personal Genome Service Pharmacogenetic Reports test can detect 33 variants for multiple genes, corresponding to more than 50 commonly prescribed medications and over-the-counter products.
The patient's past medical history was significant for CKD on nightly peritoneal dialysis, T2D mellitus, peripheral neuropathy, gastroesophageal reflux disease, hypertension, and chronic pain.
To investigate the link between organic food consumption and cancer risk, study authors conducted a population-based prospective cohort study among French adults.
In an effort to cut high drug costs, the prices paid by Medicare for certain prescription drugs would be based on those in other advanced industrial nations.
One in two women and one in three men will develop dementia, stroke, or parkinsonism during their lifetime.
In multivariable models, associations were observed between cardiovascular risk factors and cerebrovascular morphology, as well as white matter hyperintensity count.
Hospitalization is associated with lower white matter integrity among older adults.
A rare but devastating polio-like virus appears to have made itself at home in the United States, partially paralyzing hundreds of children.
Nine recent cases of a rare, polio-like disorder in children are being investigated in Illinois, health officials said yesterday.
A rare, polio-like condition in children is on the rise again in the United States, with 38 confirmed cases in 16 states so far this year.
Standard pen needles have an outer cover and removable inner needle cover, while safety pen needles have an outer cover and a fixed inner needle shield that is not removed before an injection.
The new guidelines place a substantial emphasis on the importance of introducing high-quality rehabilitation early in these patients.
The Company has obtained Investigational New Drug clearance for Phase 1/2a trials of Q-Cells in both TM and amyotrophic lateral sclerosis.
Every nine minutes, a patient in a U.S. hospital dies because a diagnosis was wrong or delayed -- resulting in 80,000 deaths a year. .
In the PREVENT study, the safety and efficacy of Soliris was compared to placebo in patients with AQP4 auto antibody-positive NMOSD (N=143).
On average, hospitals mark up drugs by 479 percent of their cost, according to a report from The Moran Company, commissioned by the PhRMA.
A significant risk factor for autoimmune encephalitis was antibody detection within a 3-week period of herpes simplex encephalitis.
Prices for drugs under shortage increase more than twice as quickly as expected in the absence of a shortage.
Cerdelga is indicated for the long-term treatment of adult patients with Gaucher disease type 1 who are CYP2D6 extensive metabolizers, intermediate metabolizers, or poor metabolizers as detected by an FDA-cleared test.
Age-specific mortality from subacute sclerosing panencephalitis, the neurodegenerative disease caused by the measles virus, is reflective of changes in measles age distributions, and the condition could disappear in the United States if measles vaccination rates remain high.
Diabetes and smoking are vascular risk factors associated with hippocampal calcification in older patients with memory issues.
Promoting generic substitution and therapeutic interchange can save money compared with spending on brand-name combination medications.
Doctors' intuition plays a role in determining how many imaging tests are ordered for a patient.
The investigators sought to explore how aortic stiffening is linked to resting cerebral blood flow and cerebrovascular reactivity in older adults.
Surgical residents feel strongly that personal financial education should be offered during medical training.
Patients report that doctors are routinely not discussing known risk factors for common causes of death.
Last year, the DEA proposed a 20% reduction in the manufacturing of controlled substances for 2018 compared to 2017.
The Environmental Protection Agency must remove the pesticide chlorpyrifos from sale in the United States within 60 days, a federal appeals court ordered yesterday.
People who feel younger than their age show fewer signs of brain aging than those who feel their age or older than their age.
Advance care planning in frail older adults does not increase patient activation or quality of life.
Delay or lack of speech, seizures, and walking/balance disorders are some of the symptoms associated with AS.
The FDA has granted Orphan Drug designation to Surface Oncology's lead investigational candidate SRF231, a potential treatment for patients with multiple myeloma.
Individual blood donations will no longer need to be tested for the Zika virus.
Anticonvulsant drugs are ineffective for chronic low back pain and can cause harm, despite a recent increase in prescribing.
Neostigmine Methylsulfate Injection, a cholinesterase inhibitor, is indicated to reverse the effects of non-depolarizing neuromuscular blockers after surgery.
CUTX-101, a subcutaneous injectable formulation of copper histidinate, is designed to supplement blood and brain copper levels in patients with Menkes disease.
Aedes aegypti mosquitoes can spread the Zika virus.
Cannabis use is associated with psychosis symptoms during adolescence.
Approximately one-third of US children and adolescents use dietary supplements.
Neurologic outcomes in children with diabetic ketoacidosis are similar regardless of the rate of administration or the NaCl content of intravenous fluids.
White matter hyperintense lesions in patients with reversible cerebral vasoconstriction syndrome change over time in a manner that parallels disease severity.
Informed consent, privacy, and justice concerns are 3 issues that should be addressed before the use of online genealogy data in criminal cases becomes widely adopted.
Brain autopsies of participants of the Rush Memory Aging project (n=428) were studied to identify the association between brain pathologies and total daily physical activity and mortality.
The FDA has granted Breakthrough Therapy designation to Lenti-D for the treatment of patients with cerebral adrenoleukodystrophy.
The Agency has received reports of serious neural tube birth defects involving the brain, spine, and spinal cord in babies born to women who received dolutegravir for HIV treatment.
These Medication Guides should be provided the first time an outpatient receives a GBCA injection at an MRI center; hospital patients are not required to receive a Medication Guide.
Evidence on whether the implementation of prescription drug monitory programs increases or decreases opioid-related overdoses was found to be "largely insufficient".
Lightning, which can result in strong electromagnetic fields, can interfere with deep brain stimulation devices.
Ventriculomegaly, Polymicrogyria Predict Epilepsy Risk Among Pediatric Patients With Cytomegalovirus Infections
Investigators retrospectively reviewed the patients' medical records and MRI images and assessed the associations between the MRI findings and neurologic outcomes, specifically neurodevelopmental achievement, epilepsy, and sensorineural hearing loss.
Negative fateful life events in midlife are associated with advanced predicted brain aging.
Investigators assessed the impact of atraumatic vs conventional needles on patient outcomes after lumbar puncture.
Women who have a later natural menopause maintain a small benefit in verbal memory compared with women with earlier menopause.
For older patients, toenail length can provide important insight into a patient's functional status.
Noting that aging humans are thought to exhibit waning neurogenesis and exercise-induced angiogenesis, researchers examined whole-autopsy hippocampi from healthy humans.
For patients with major depressive disorde, relapse is associated with brain cortical changes over two years.
Among pregnant women with Zika virus infection, birth defects were reported more often in fetuses and infants whose mothers had been infected with the virus early in their pregnancies.
Predicting Neurological Outcome in Unconscious Cardiac Arrest With White Matter Fractional Anisotropy
The normalized WWM-FA value demonstrated the greatest prognostic accuracy compared with MRI sequences or standard criteria for unfavorable neurological outcome.
3 years after menopausal HT, change in brain volumes were not significantly different from placebo.
Investigators examined plasma tau concentrations in blood samples obtained from patients who received general anesthesia for surgery.
Significantly stronger neural responses in superior parietal cortices during memory encoding in T1DM.
Prompt identification may help reduce the risk for subsequent renal failure and minimize overall disease burden.
OV101 has previously been granted Orphan Drug status for Fragile X and Fast Track status for Angelman syndrome.
MRI had lower health benefit and higher cost compared with no follow-up after normal CT findings.
Deleterious effect of alcohol dependence on frontal cortical volumes also compounded by drug use.
Presence of bacteria is associated with higher neuroinflammatory markers in mice and humans.
Findings in early clinical studies that evaluate drugs or devices for chronic conditions are often exaggerated.
A low risk of serotonin syndrome is seen in association with concomitant use of triptans and SSRIs.
Uber has a new system that allows physician offices to book rides for patients up to 30 days in advance.
A significantly greater proportion of patients with early hyperoxia exposure experienced poor neurological function vs patients without exposure.
Cognitive change, diplopia, dysarthria, dysphagia, focal sensory deficit, focal motor deficit, headache, and imbalance, were noted in 47% of the cohort.
Ability to identify facial paralysis increases with the severity of the condition.
The FDA announced the approval of the RadioGenix System.
HIV-positive patients with virological suppression did not have different rates of aging-relating cognitive decline compared with HIV-negative patients.
Another case of unusual amnestic syndrome that includes bilateral hippocampal lesions on MRI has been described.
The FDA has accepted Alnylam's New Drug Application for patisiran, and investigational drug for treating hereditary aTTR amyloidosis, for priority review.
In the second half of 2016, there was an increase in the number of birth defects potentially related to Zika virus infection.
TAK-426, and investigational drug for Zika virus, has been granted Fast Track desgination by the FDA.
The HCV treatment, sofosbuvir was found to be effective in treating the Zika virus.
Patients who underwent C7 nerve transfer and rehabilitation experienced better functional improvement than those who underwent rehabilitation alone.
The CES exhibit has presented an impressive array of medical technology.
Neurology Advisor Articles
- Survival in Parkinson Disease Dependent on Parkinsonian Type, Characteristics
- Case Study Report: Herbal Supplement Kratom Associated With Neonatal Abstinence Syndrome
- Mobile Health Apps for Headache: An Ongoing Search for Clinical Relevancy
- CBD Superior to Placebo, Similar to AEDs for Managing Epilepsy Syndromes
- Young Fresh Frozen Plasma Infusion Safe, Feasible in Alzheimer Disease
- Alemtuzumab Linked to Clinical and MRI Disease Remission in Multiple Sclerosis
- Very Early Mobilization After Stroke Does Not Improve Survival Over Usual Care
- Cognitive Decline Worsens With Memantine, ChEIs in Patients With Alzheimer's
- Cervical Dysfunction Needs Clarification to Identify Link With Headache
- Levodopa Inhalation Powder Approved for Parkinson Disease
- Can Early Initiation of Direct Oral Anticoagulants Prevent Recurrent AFib-Related Stroke?
- Hydrocephalus May Be a Complication of Congenial Zika Syndrome
- Higher CSF NfL Protein Levels Linked to Risk for Mild Cognitive Impairment
- Addressing Cognitive Impairment in Pediatric MS: Expert Q&A
- How the Government Shutdown Affects FDA Activities