General Neurology

CNS Abnormalities Common in Erdheim-Chester Disease

CNS Abnormalities Common in Erdheim-Chester Disease

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Cognitive change, diplopia, dysarthria, dysphagia, focal sensory deficit, focal motor deficit, headache, and imbalance, were noted in 47% of the cohort.

 Are Casual Observers Able to Accurately Localize Areas of Facial Paralysis?

Are Casual Observers Able to Accurately Localize Areas of Facial Paralysis?

Ability to identify facial paralysis increases with the severity of the condition.

US Will Produce Radioisotope for MRI, FDA Says

US Will Produce Radioisotope for MRI, FDA Says

The FDA announced the approval of the RadioGenix System.

Ethical Considerations in New Coma Research

Ethical Considerations in New Coma Research

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Research on therapies that may rouse a patient in a persistent vegetative state needs to include the ethical considerations of waking a patient in a state of incomplete recovery.

Aging-Related Brain Changes No Different in HIV Positive, Negative

Aging-Related Brain Changes No Different in HIV Positive, Negative

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HIV-positive patients with virological suppression did not have different rates of aging-relating cognitive decline compared with HIV-negative patients.

FDA Expands Pediatric Age Range for Contrast Agent

FDA Expands Pediatric Age Range for Contrast Agent

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The FDA has approved an expanded age range for MultiHance contrast agent.

Fentanyl Use Associated With Amnesia: Case Report

Fentanyl Use Associated With Amnesia: Case Report

Another case of unusual amnestic syndrome that includes bilateral hippocampal lesions on MRI has been described.

FDA Reviewing NDA for Hereditary aTTR Amyloidosis Gene-Silencing Therapy

FDA Reviewing NDA for Hereditary aTTR Amyloidosis Gene-Silencing Therapy

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The FDA has accepted Alnylam's New Drug Application for patisiran, and investigational drug for treating hereditary aTTR amyloidosis, for priority review.

Zika Virus-Related Birth Defects Saw Increase in 2016

Zika Virus-Related Birth Defects Saw Increase in 2016

In the second half of 2016, there was an increase in the number of birth defects potentially related to Zika virus infection.

Zika Vaccine Fast-Tracked by FDA

Zika Vaccine Fast-Tracked by FDA

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TAK-426, and investigational drug for Zika virus, has been granted Fast Track desgination by the FDA.

Hepatitis C Drug May Treat Zika Virus

Hepatitis C Drug May Treat Zika Virus

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The HCV treatment, sofosbuvir was found to be effective in treating the Zika virus.

Spastic Arm Paralysis Improved With C7 Nerve Transfer

Spastic Arm Paralysis Improved With C7 Nerve Transfer

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Patients who underwent C7 nerve transfer and rehabilitation experienced better functional improvement than those who underwent rehabilitation alone.

CES 2018: Top Medical Technology

CES 2018: Top Medical Technology

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The CES exhibit has presented an impressive array of medical technology.

Are Benefits of Cannabis Therapy Being Blown Out of Proportion?

Are Benefits of Cannabis Therapy Being Blown Out of Proportion?

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Due to inadequate blinding in clinical trials, the benefits associated with medical cannabis therapy may be overestimated.

Brodmann Area 25 May Play Pivotal Role in Controlling Blood Pressure

Brodmann Area 25 May Play Pivotal Role in Controlling Blood Pressure

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Stimulation of the other brain structures resulted in no significant blood pressure changes among the studied participants.

Top 10 Medical Innovations We'll See in 2018

Top 10 Medical Innovations We'll See in 2018

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These are the top 10 medical innovations expected to be seen in 2018.

Decision Support Systems: Helpful or Harmful?

Decision Support Systems: Helpful or Harmful?

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The automated diagnosis suggestion at the top of the EKG strip is the output of what is known as a decision support system.

Gadolinium Buildup Does Not Affect Cognition, New Research Finds

Gadolinium Buildup Does Not Affect Cognition, New Research Finds

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Cognitive decline was not accelerated because of gadolinium buildup in the brain.

Guidelines for Cervical, Ocular Vestibular Evoked Myogenic Potential Testing: AAN

Guidelines for Cervical, Ocular Vestibular Evoked Myogenic Potential Testing: AAN

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The American Academy of Neurology has released new clinical practice guidelines addressing the use of cervical and ocular vestibular evoked myogenic potential testing.

Intranasal, Intramuscular Naloxone Equally As Effective for Opioid Overdose

Intranasal, Intramuscular Naloxone Equally As Effective for Opioid Overdose

Higher-concentration intranasal naloxone has similar efficacy to that of intramuscular naloxone given at the same dose for reversal of opioid overdose.

Suboptimal Neuromotor Development May Increase Genetic Risk for Schizophrenia

Suboptimal Neuromotor Development May Increase Genetic Risk for Schizophrenia

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Nonoptimal infant neuromotor development was linked to genetic risk for schizophrenia, but not bipolar disorder.

Nonalcoholic Fatty Liver Disease Associated With Reduced Total Cerebral Volume

Nonalcoholic Fatty Liver Disease Associated With Reduced Total Cerebral Volume

Smaller total cerebral brain volume is linked with nonalcoholic fatty liver disease.

Neurologic Response to Glucose Diminished in Diabetes

Neurologic Response to Glucose Diminished in Diabetes

In obese adults with T2DM, the rise of brain glucose levels is blunted during hyperglycemia.

Force Analysis May Aid in Determining Neurosurgeon Skill Level

Force Analysis May Aid in Determining Neurosurgeon Skill Level

Surgeon skill level may be differentiated by force-sensing bipolar forceps and force analysis.

Diagnosing Tuberculous Meningitis: Overcoming Challenges

Diagnosing Tuberculous Meningitis: Overcoming Challenges

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Diagnosis of TB meningitis is challenging, although new, next-generation rapid POC testing holds promise for greatly improved sensitivity.

West Nile Virus Linked to Neurologic Abnormalities

West Nile Virus Linked to Neurologic Abnormalities

Abnormalities on neurologic examination were found several years after patients were infected with West Nile virus.

Altered Hemodynamics May Influence White Matter Hyperintensity Development

Altered Hemodynamics May Influence White Matter Hyperintensity Development

There was a linear link between white matter hyperintensity volume and RA pressure in chronic valvular heart disease.

Development of Guillain-Barré Syndrome Associated With Zika Virus Infection

Development of Guillain-Barré Syndrome Associated With Zika Virus Infection

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Infection with the Zika virus may increase the risk for development of Guillain-Barré syndrome.

Publication Bias in Neurology Research: Why It Matters and Why It Needs to Change

Publication Bias in Neurology Research: Why It Matters and Why It Needs to Change

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Withholding negative research results not only skews scientific evidence but also puts into question the whole validity of medical research.

Functional Brain Connectivity Has Familial, Heritable Patterns

Functional Brain Connectivity Has Familial, Heritable Patterns

The findings may help to better characterize normative development and altered patterns of brain activity that may serve as biomarkers for neurological conditions.

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