General Neurology

Study Identifies Area Postrema Syndrome Identification Criteria in NMOSD

Study Identifies Area Postrema Syndrome Identification Criteria in NMOSD

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Investigators sought to determine how prevalent and severe intractable nausea, vomiting, or hiccups are in patients with AQP4-IgG-positive NMOSD.

Tap Water in Neti Pot Linked to Brain Infection, Death From <i> Balamuthia mandrillaris </i>

Tap Water in Neti Pot Linked to Brain Infection, Death From Balamuthia mandrillaris

The use of tap water in a nasal-flushing Neti pot likely led to a Seattle woman's death from a Balamuthia mandrillaris brain infection.

Systemic Vascular Health Associated With Widespread Brain Changes

Systemic Vascular Health Associated With Widespread Brain Changes

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Systemic vascular health measured as a composite of recent cardiovascular and metabolic chronic conditions was associated with medial temporal lobe thinning, widespread cerebral hypoperfusion, and poor microstructural integrity.

Rituximab Effects in Neuromyelitis Optica Spectrum Disorders

Rituximab Effects in Neuromyelitis Optica Spectrum Disorders

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Investigators sought to determine whether rituximab would have long-term effects on total and specific immunoglobulins in patients with neuromyelitis optica spectrum disorders.

Guidance for Antibiotic Use in Myasthenia Gravis

Guidance for Antibiotic Use in Myasthenia Gravis

As infection may also lead to worsening symptoms in patients with myasthenia gravis, clinicians must balance prompt and adequate treatment of infection with the risk that some antibiotics can aggravate the condition.

Neuropsychological Deficits Common in Pediatric Survivors of Cardiac Arrest

Neuropsychological Deficits Common in Pediatric Survivors of Cardiac Arrest

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Investigators examined neuropsychological outcomes of children who survived pediatric cardiac arrest.

CDC: Acute Flaccid Myelitis Cases Appear to Have Peaked for 2018

CDC: Acute Flaccid Myelitis Cases Appear to Have Peaked for 2018

The number of cases of acute flaccid myelitis in the United States this year appears to have peaked and is expected to decline for the remainder of 2018.

Assessing for Periodic Paralysis With Long Exercise Test Effective

Assessing for Periodic Paralysis With Long Exercise Test Effective

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A recent study supports the use of the long exercise test to diagnose periodic paralysis.

Left Atrial Enlargement Linked to Vascular Brain Injury

Left Atrial Enlargement Linked to Vascular Brain Injury

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Investigators examine the association between LAD and vascular brain injury on brain MRI.

Diagnosing Retinal Vasculopathy With Cerebral Leukoencephalopathy: Case Report

Diagnosing Retinal Vasculopathy With Cerebral Leukoencephalopathy: Case Report

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Investigators reviewed a case study of 2 brothers with retinal vasculopathy with cerebral leukoencephalopathy to learn more about this rare disease.

Living With Periodic Paralysis: An Interview With Jacob Levitt, MD

Living With Periodic Paralysis: An Interview With Jacob Levitt, MD

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Neurology Advisor spoke with Jacob Levitt, MD, for his unique medical and patient perspectives on PP.

Reducing Residential Lead Exposure May Lower Lead Blood Levels

Reducing Residential Lead Exposure May Lower Lead Blood Levels

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Clinicians and public health practitioners should advise expectant parents on ways to prevent childhood lead exposure.

Access to In-Home Support Soon to Be Available for Seniors

Access to In-Home Support Soon to Be Available for Seniors

In-home services such as help with household chores and caregiver respite will be available to seniors with private Medicare Advantage plans in more than 20 states next year.

Preterm birth associated with lower high school academic performance

In this retrospective cohort study, birth at earlier gestational age (GA) was associated with worse survival rates and increased hospitalization rates in the first 10 years of life, with respiratory diagnoses being the most common reason for admission.

One-Third of Peds Medication Errors Due to Usability Issues

One-Third of Peds Medication Errors Due to Usability Issues

More than one-third of pediatric patient safety reports in 2012 to 2017 that were related to electronic health record use were attributed to usability issues.

No Efficacy Signal for Fluoxetine in EV-D68 Acute Flaccid Myelitis

No Efficacy Signal for Fluoxetine in EV-D68 Acute Flaccid Myelitis

The antiviral agent fluoxetine is well tolerated but is not effective for patients with proven or presumptive enterovirus D68-associated acute flaccid myelitis.

Approaches for Better Diagnosis of Pediatric Multiple Sclerosis

Approaches for Better Diagnosis of Pediatric Multiple Sclerosis

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Pediatric MS is predominantly inflammatory in nature, with a presentation that is similar to a number of other conditions.

FDA Proposes New Restrictions on Sale of Electronic Nicotine Delivery Systems

FDA Proposes New Restrictions on Sale of Electronic Nicotine Delivery Systems

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The announcement comes in the wake of results from the 2018 National Youth Tobacco Survey which showed a 78% increase in current e-cigarette use among high school students from 2017 to 2018.

FDA Issues Safety Alert Regarding Intrathecal Delivery of Pain Meds

FDA Issues Safety Alert Regarding Intrathecal Delivery of Pain Meds

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The FDA has issued a safety communication regarding the risks associated with implanted pumps for intrathecal administration of pain medications.

Researchers Identify Coffee Component That May Provide Neuroprotection

Researchers Identify Coffee Component That May Provide Neuroprotection

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The authors found that the compounds known as phenylindanes inhibited the aggregation of the amyloidgenic proteins beta-amyloid and tau.

Nusinersen May Be Effective for Short-Term Motor Function Improvements in Spinal Muscular Atrophy

Nusinersen May Be Effective for Short-Term Motor Function Improvements in Spinal Muscular Atrophy

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Nusinersen, an antisense oligonucleotide that increases functional SMN protein production from SMN2, was clinically effective for improving motor function.

Cannabidiol Gets Orphan Drug Status for Preventing Ischemia-Reperfusion Injury

Cannabidiol Gets Orphan Drug Status for Preventing Ischemia-Reperfusion Injury

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The designation was granted to Revive Therapeutics, a company that specializes in cannabis-based pharmaceuticals.

HHS: Updated Physical Activity Guidelines for Americans Released

HHS: Updated Physical Activity Guidelines for Americans Released

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This guidance, updated for the first time since 2008, provides evidence-based recommendations for children (ages 3-17) and adults.

FDA Clears Patient Controller Platform for Stimwave's Neuromodulation Device

FDA Clears Patient Controller Platform for Stimwave's Neuromodulation Device

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The new software enables patients to fine-tune the power level and modify programs that were pre-programmed by their clinician to control pain.

Quitting Cannabis Tied to Improved Memory

Quitting Cannabis Tied to Improved Memory

Abstaining from cannabis is associated with improvements in memory and verbal learning in adolescents and young adults.

Critical Illness and the Brain: Managing Risk for Cognitive Adverse Effects

Critical Illness and the Brain: Managing Risk for Cognitive Adverse Effects

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The results highlight the importance of evaluating and monitoring cognitive function in individuals with recent critical illness or major infections, especially if they are already at risk for dementia.

New Diagnostic Criteria for Neurosarcoidosis: What You Need to Know

New Diagnostic Criteria for Neurosarcoidosis: What You Need to Know

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The new guidelines will facilitate the design and development of clinical trials to test new therapies to minimize the burden of neurologic disability produced by neurosarcoidosis.

Higher Serum Cortisol Level Linked to Lower Brain Volumes

Higher Serum Cortisol Level Linked to Lower Brain Volumes

Higher serum cortisol level is associated with lower brain volumes and impaired memory in asymptomatic younger to middle-aged adults.

FDA-Approved Test Provides Pharmacogenetic Reports Directly to Consumers

FDA-Approved Test Provides Pharmacogenetic Reports Directly to Consumers

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The 23andMe Personal Genome Service Pharmacogenetic Reports test can detect 33 variants for multiple genes, corresponding to more than 50 commonly prescribed medications and over-the-counter products.

Case Report Highlights Variable Presentation of Serotonin Syndrome

Case Report Highlights Variable Presentation of Serotonin Syndrome

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The patient's past medical history was significant for CKD on nightly peritoneal dialysis, T2D mellitus, peripheral neuropathy, gastroesophageal reflux disease, hypertension, and chronic pain.

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