Glioblastoma

Quality of Life in Glioblastoma Not Worsened by Tumor-Treating Fields Plus Temozolomide

Quality of Life in Glioblastoma Not Worsened by Tumor-Treating Fields Plus Temozolomide

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Participants receiving TTFields with temozolomide experienced significantly longer deterioration-free survival for global health vs those receiving temozolomide only.

No Survival Benefit With Lomustine Plus Bevacizumab in Glioblastoma

No Survival Benefit With Lomustine Plus Bevacizumab in Glioblastoma

Treatment with lomustine plus bevacizumab does not show a survival advantage over treatment with lomustine alone in patients with glioblastoma.

Glioblastoma Treatment May Benefit From Vaccine-Chemotherapy Combo

Glioblastoma Treatment May Benefit From Vaccine-Chemotherapy Combo

Nearly half of the patients in the trial survived more than 5 years after they were given the vaccine-chemotherapy treatment.

Researchers Debunk Rumored Link Between Glioblastoma, Cytomegalovirus

Researchers Debunk Rumored Link Between Glioblastoma, Cytomegalovirus

Despite previous reports, researchers have found no signs of a link between cytomegalovirus and brain tumors including glioblastoma.

Radiomic Method Helps Predicts Glioblastoma Outcome

Radiomic Method Helps Predicts Glioblastoma Outcome

Radiomic-based superpc signature stratifies patients into low- or high-risk groups for PFS, OS.

Total Resection Improves Survival in Glioblastoma Multiforme

Total Resection Improves Survival in Glioblastoma Multiforme

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GTR increases survival by about 61% at 1 year compared to STR.

In Glioblastoma, Personalized Medicine is a Challenge

In Glioblastoma, Personalized Medicine is a Challenge

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The role of antiangiogenic agents continues to evolve in the treatment of CNS cancers.

Glioma Signature Predicts Outcomes in Glioblastoma

Glioma Signature Predicts Outcomes in Glioblastoma

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Researchers were able to identify 8 genes that showed the highest association to outcomes.

Combined Modality Therapy Superior in Glioblastoma

Combined Modality Therapy Superior in Glioblastoma

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Multiple modalities were found to be superior to single modality therapies in elderly patients with glioblastoma.

Valproic Acid Beneficial in Glioblastoma, But Not Low-Grade Glioma

Valproic Acid Beneficial in Glioblastoma, But Not Low-Grade Glioma

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Interestingly, the risk of death and tumor progression was increased in low-grade gliomas.

Brain Tumor Histology and Incidence in Adolescents and Young Adults

Brain Tumor Histology and Incidence in Adolescents and Young Adults

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Over 10 000 brain and CNS tumors are diagnosed in adolescent and young adults each year.

Electromagnetic Field Therapy Promising for Glioblastoma Treatment

Electromagnetic Field Therapy Promising for Glioblastoma Treatment

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Two years post-enrollment, 43% of patients in the combination therapy group were alive.

VIDEO: Global Coalition to Design Adaptive Clinical Trial for Glioblastoma

VIDEO: Global Coalition to Design Adaptive Clinical Trial for Glioblastoma

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The adaptive trial design will allow GBM patients to benefit from precision medicine.

FDA Expands Approval of Optune Device for Glioblastoma Multiforme

FDA Expands Approval of Optune Device for Glioblastoma Multiforme

The device may now be used to treat newly-diagnosed patients in combination with temozolomide.

Chemoradiation for Glioblastoma Reduces Brain Volume

Chemoradiation for Glioblastoma Reduces Brain Volume

A reduction primarily in grey matter and expansion of the brain's ventricles was observed.

Combination Therapy May Eradicate Glioblastoma Cells

Combination Therapy May Eradicate Glioblastoma Cells

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The combination therapy specifically targets glioblastoma cells.

Glioma Patients May Be Good Candidates for Single-Agent Phase 1 Trials

Glioma Patients May Be Good Candidates for Single-Agent Phase 1 Trials

Patients who meet standard eligibility requirements may make good candidates for single-agent trials.

Targeted Radiation Preserves Cognition in Brain Metastases Tx

Targeted Radiation Preserves Cognition in Brain Metastases Tx

Survival rates were similar for both methods, but targeted radiation helped preserve cognition.

Inhibition of Enzyme GLDC Could Kill Off Glioblastoma Cells

Inhibition of Enzyme GLDC Could Kill Off Glioblastoma Cells

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Researchers also found mechanisms of cell survival in ischemic regions of brain tumor.

Bevacizumab is Safe, Effective for Recurrent Glioblastoma

Bevacizumab is Safe, Effective for Recurrent Glioblastoma

70.8% of patients saw improved performance status while on single-agent bevacizumab.

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