Plasma neurofilament light concentrations may be able to distinguish several neurodegenerative conditions. Results indicate that NfL may be promising as a clinical tool or for use in clinical trials.

Patients with dementia or Alzheimer disease (AD) have a significantly increased risk for seizures compared with patients without AD or dementia.

The level of α-syn heteroaggregates in red blood cells may be a tool for the diagnostic work-up in early Alzheimer disease diagnosis.

Women with Alzheimer disease have higher levels of brain metabolism compared with men, which may contribute to their superior verbal memory performance at various disease stages.

Previous epidemiological studies identified healthy lifestyle factors that can lower an individual’s risk for developing dementia in Alzheimer disease; this study investigates the extent to which combining those factors reduces dementia risk.

Using data from the CARDIA study, it has been shown that smoking in early adulthood to midlife is associated with midlife cognitive impairment, and that quitting smoking, even in midlife, can have cognitive benefits.