Investigators aimed to evaluate the efficacy of combined treatment (antidepressants plus STPP) vs antidepressants (with or without brief supportive psychotherapy) on depressive symptoms in adults in acute-phase depression.

Investigators searched publication databases for randomly assigned controlled trials comparing TBI interventions with face-to-face interventions in the setting of first-episode psychosis, high-risk for psychosis, schizophrenia, schizoaffective disorder, schizophreniform psychotic disorder, or nonaffective psychosis.

Sharp increase seen in stroke mortality with increasing age; steeper decline seen for ischemic versus hemorrhagic stroke mortality

Authors say respectful maternity care may help address maternal morbidity in Black women

Period prevalence of all antipsychotic prescriptions increased 3.3 percent per year from 2000 to 2019

Risk found to be similar across racial, ethnic groups of older adults in the United States

Researchers sought to evaluate 3 muscle-enriched biomarkers in the serum of patients with BMD over 4 years-time and correlations with disease severity, disease progression, and dystrophin levels in BMD.

In a prospective, longitudinal study, researchers assessed the effect of demographics, pre-COVID-19 comorbidities, index COVID-19 hospitalization metrics, and life stressors on 6- and 12-month outcome metrics in adult patients post-COVID-19 hospitalization.

The cost effectiveness, risks, and benefits of spinal cord stimulation for chronic pain were assessed in a retrospective comparative effectiveness study.

Investigators sought to identify exercise options that would be most effective at managing symptoms among patients with fibromyalgia.

However, expansion of telehealth yielded net increase in care for major depressive disorder, anxiety, and adjustment disorder

Findings seen for children in both lower and upper elementary grades, although differences seen by sex and age

More than half using cannabis as a treatment for chronic pain report substituting cannabis in place of other pain medications

Estimated 32.8 percent of individuals lose vaccine-derived immunity by age 18 years in the United States

Researchers sought to determine the independent associations of general and central adiposity with risk for ischemic stroke, intracerebral hemorrhage, and subarachnoid hemorrhage.

In a systematic review and meta-analysis, researchers evaluated accelerometer-measured sedentary behavior and physical activity between patients with MS and healthy control individuals.

Leqembi is a humanized IgG1 monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta.

The BLA is supported by data from the phase 3 MycarinG study.

Both massed and intensive forms of prolonged exposure therapy tied to six-month improvements in PTSD

Cluster of inflammation markers positively associated with multiple sclerosis-related species

Association seen between infant exposure to acid-suppressive medications and increased asthma risk in offspring

Layered approach involves initially combining lifestyle interventions, self-management, and first-line pharmacotherapy

In a prospective, observational study, researchers investigated the prevalence of silent AF and associated risk factors in patients assessed for OSA or with known OSA.

Researchers sought to examine the association between apathy and function longitudinally across dementia severity.

Researchers sought to determine the association between commonly evaluated risk factors and poststroke detection of new AF in the STROKE AF cohort monitored by ICM.

Investigators conducted a prospective, observational, single-center study to assess outcomes following microvascular decompression among patients with trigeminal neuralgia.

Approval of Leqembi comes after controversial approval in 2021 of Aduhelm, which met with criticism over concerns about that drug’s effectiveness, safety, pricing

Significant additive APOE ε4 interactions seen with PTSD and TBI in veterans of European ancestry

Authors recommend against clinical assessment alone when neuromuscular drugs are administered due to insensitivity of assessment

Non-Hispanic Asian children and adolescents have the highest vaccination coverage, followed by Hispanic/Latino children