Generic Name and Formulations:
Clobetasol propionate 0.025%; crm.
Encore Dermatology, Inc.
RECENT UPDATESMonograph added.
Indications for IMPOYZ:
Moderate to severe plaque psoriasis.
≥18yrs: apply thin layer twice daily; max 50g/week and 2 consecutive weeks' treatment per course. Discontinue when control is achieved. Wash hands after application. Do not occlude.
<18yrs: not recommended.
Avoid use on face, scalp, axilla, groin, or other intertriginous areas. Do not use for diaper dermatitis or on pre-existing skin atrophy. Risk of HPA axis suppression with high-potency steroids, prolonged use, application to large surface area, use of occlusive dressings, altered skin barrier, liver failure, young age; discontinue gradually, reduce dose, or substitute with less potent corticosteroid if occurs. Treat infection if present; discontinue if infection persists or worsens. Avoid abrupt cessation in chronic use. Reevaluate periodically. Pregnancy. Nursing mothers.
Application site discoloration, burning, itching, irritation, dryness, folliculitis, acneiform eruptions, hypertrichosis, hypopigmentation, perioral dermatitis, allergic contact dermatitis (discontinue if irritation occurs), secondary infection, striae, miliaria; HPA axis suppression (esp. in children); rare: Cushing's syndrome, hyperglycemia, glucosuria.
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