Intracerebral Hemorrhage

Clinical, Radiologic Markers Predictive of Cortical Superficial Siderosis in ICH Identified

Clinical, Radiologic Markers Predictive of Cortical Superficial Siderosis in ICH Identified

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Investigators identify clinical and neuroimaging markers associated with the presence of cortical superficial siderosis and the risk for recurrent ICH.

Intracerebral Hemorrhage Risk Decreased With Increasing Cholesterol, Statin Use

Intracerebral Hemorrhage Risk Decreased With Increasing Cholesterol, Statin Use

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An inverse relationship was discovered between rising cholesterol levels and decreased risk for intracerebral hemorrhage in new statin users.

Tranexamic Acid Provides Short-Term, But Not Long-Term, Benefits Following Intracerebral Hemorrhage

Tranexamic Acid Provides Short-Term, But Not Long-Term, Benefits Following Intracerebral Hemorrhage

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Patients with intracerebral hemorrhage who were admitted to acute stroke units were randomly assigned to either 1 gram intravenous tranexamic acid followed by an 8-hour infusion of 1 gram tranexamic acid or matched placebo.

Prediction Algorithm Stratifies ICH Patients at Risk for Hematoma Expansion

Prediction Algorithm Stratifies ICH Patients at Risk for Hematoma Expansion

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While developing the hematoma expansion prediction score, associations between hematoma expansion and blend sign, any intrahematoma hypodensity, and time from onset to noncontrast computed tomography <2.5 hours were found.

Cerebral Microbleeds Do Not Predict 3-Month Death or Disability in Intracerebral Hemorrhage

Cerebral Microbleeds Do Not Predict 3-Month Death or Disability in Intracerebral Hemorrhage

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Investigators performed a pre-planned secondary analysis of the open-label, randomized Antihypertensive Treatment of Acute Cerebral Hemorrhage 2 study, specifically on the magnetic resonance images obtained during the intensive blood pressure lowering portion of the trial.

Predicting Hemorrhage Risk in Patients With Vascular Malformations

Predicting Hemorrhage Risk in Patients With Vascular Malformations

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The investigators of this study did not compare pre- or post-hemorrhage data, precluding their ability to determine the applicability of the findings for improving clinical practice.

Intensive Blood Pressure Lowering Provides No Mortality Benefit in Acute Intracerebral Hemorrhage

Intensive Blood Pressure Lowering Provides No Mortality Benefit in Acute Intracerebral Hemorrhage

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Investigators conducted a meta-analysis of trials that reported functional outcomes and mortality rates among patients with intracerebral hemorrhage following intensive blood pressure lowering.

Predicting Intracerebral Hemorrhage Outcomes With Peak Perihemorrhagic Edema

Predicting Intracerebral Hemorrhage Outcomes With Peak Perihemorrhagic Edema

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Further research may be necessary to better understand the pathophysiologic mechanisms involved in perihemorrhagic edema evolution and ICH.

Stroke, ICH Risk Elevated in Seniors With AFib Taking Anticoagulants

Stroke, ICH Risk Elevated in Seniors With AFib Taking Anticoagulants

For patients with CKD and atrial fibrillation, anticoagulants are linked with an increased risk of ischemic stroke.

Intracerebral Hemorrhage-Related Hospital Mortality Reduced With Prior NOAC Use

Intracerebral Hemorrhage-Related Hospital Mortality Reduced With Prior NOAC Use

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Outcomes in intracerebral hemorrhage are less severe in patients with prior NOAC use.

ENCHANTED Update: No Role for Low-Dose Alteplase After All?

ENCHANTED Update: No Role for Low-Dose Alteplase After All?

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Results from a secondary analysis of the ENCHANTED trial add to a pile of weak data that likely will not affect clinical practice.

Noncontrast CT Markers Predict Hematoma Growth Risk in Hemorrhagic Stroke

Noncontrast CT Markers Predict Hematoma Growth Risk in Hemorrhagic Stroke

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Surprisingly, no evidence was found to suggest that patients with these markers benefit from intensive blood pressure reduction.

After Stroke, Intensive Antiplatelet Therapy Has Benefits, Drawbacks

After Stroke, Intensive Antiplatelet Therapy Has Benefits, Drawbacks

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Intensive antiplatelet therapy appears to reduce risk of recurrence immediately after stroke, but may pose risks further out.

Intracerebral Hemorrhage Outcomes Improved With Anticoagulants

Intracerebral Hemorrhage Outcomes Improved With Anticoagulants

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Resumption of oral anticoagulants after intracerebral hemorrhage was found to improve outcomes at 1 year.

In Intracerebral Hemorrhage, Intensive BP Lowering Has Little Impact on Outcomes

In Intracerebral Hemorrhage, Intensive BP Lowering Has Little Impact on Outcomes

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The investigators reported no difference in 3-month mortality rates across all 5 studies included in the meta-analysis.

Oral Anticoagulation After ICH: Risks and Outcomes

Oral Anticoagulation After ICH: Risks and Outcomes

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Restarting anticoagulation after both nonlobar and lobar ICH was associated with decreased mortality.

Medical Complications After ICH: Changes in the Last Decade

Medical Complications After ICH: Changes in the Last Decade

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As more patients survive ICH, emphasis is slowly shifting from survival to improving ICH-related morbidity and optimization of functional recovery.

Cilostazol Helps Prevent Secondary Stroke But Not Without Risk

Cilostazol Helps Prevent Secondary Stroke But Not Without Risk

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Optimal antiplatelet treatment has yet to be determined for stroke survivors with prior intracerebral hemorrhage.

Dementia, Depression Common After Intracerebral Hemorrhage

Dementia, Depression Common After Intracerebral Hemorrhage

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Among ICH survivors, 63% developed both depression and dementia during a 5-year follow-up study.

Pushing the Limits of Endovascular Therapy for Acute Ischemic Stroke

Pushing the Limits of Endovascular Therapy for Acute Ischemic Stroke

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Recent research found benefits in outcome outweighed any increase in hemorrhagic complications in patients with large infarcts.

Antiplatelet Use Linked to Hematoma Growth, Outcomes in Intracerebral Hemorrhage

Antiplatelet Use Linked to Hematoma Growth, Outcomes in Intracerebral Hemorrhage

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Notably, the location of ICH influenced the association with hematoma volume and growth in patients with prior antiplatelet use.

Cerebral Microbleeds and Risk of Intracerebral Hemorrhage After Stroke

Cerebral Microbleeds and Risk of Intracerebral Hemorrhage After Stroke

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Cerebral microbleeds increase the risk for symptomatic ICH after thrombolysis for acute ischemic stroke.

Hypocalcemia May Worsen Bleeding in Intracerebral Hemorrhage

Hypocalcemia May Worsen Bleeding in Intracerebral Hemorrhage

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Lower serum calcium levels correlate with risk of hematoma expansion in intracerebral hemorrhage.

Risk Factors for Dementia Vary After Intracerebral Hemorrhage

Risk Factors for Dementia Vary After Intracerebral Hemorrhage

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Risk factors differ for early vs late-onset dementia after ICH.

Blood Pressure Management Is Only Part of the Story in Intracerebral Hemorrhage

Blood Pressure Management Is Only Part of the Story in Intracerebral Hemorrhage

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A joint medical and surgical approach may ensure the best outcome.

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