Ischemic Stroke

Congenital Heart Disease, Hispanic Ethnicity Associated With Increased Mortality in Pediatric Arterial Ischemic Stroke

Congenital Heart Disease, Hispanic Ethnicity Associated With Increased Mortality in Pediatric Arterial Ischemic Stroke

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The investigators were unable to determine which type of congenital heart disease or which type of ventricular assist device, if used, played a role in mortality outcomes.

Tenecteplase Improves Reperfusion and Functional Outcome in Ischemic Stroke

Tenecteplase Improves Reperfusion and Functional Outcome in Ischemic Stroke

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The findings from this trial are limited to only ischemic stroke patients with large-vessel occlusion who are deemed appropriate for thrombolysis.

Ceftriaxone More Cost-Effective Than Standard Care for Post-Stroke Infection Prevention

Ceftriaxone More Cost-Effective Than Standard Care for Post-Stroke Infection Prevention

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There were no differences between the ceftriaxone and standard care groups in terms of institutional care resources, out-of-pocket expenses, or productivity losses.

Sickle Cell Trait Does Not Reliably Predict Ischemic Stroke in African Americans

Sickle Cell Trait Does Not Reliably Predict Ischemic Stroke in African Americans

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Sickle cell trait is not associated with ischemic stroke and should not be relied upon as a sole predictor of stroke in African Americans.

ARISE II Demonstrates Improved Reperfusion With EmboTrap in Ischemic Stroke

ARISE II Demonstrates Improved Reperfusion With EmboTrap in Ischemic Stroke

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The lack of a comparator group as well as the relatively small patient sample represents potential limitations of this study.

Infarct Volume Predictive of Functional Outcome After Acute Ischemic Stroke

Infarct Volume Predictive of Functional Outcome After Acute Ischemic Stroke

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Variations in reperfusion rates as well as MRI assessments among included studies represent possible limitations of this meta-analysis.

Predicting Stroke Subtype Risk With Retinal Microvascular Abnormalities

Predicting Stroke Subtype Risk With Retinal Microvascular Abnormalities

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The results suggest a noninvasive method for predicting individualized risk for certain stroke subtypes.

Worse Stroke Outcomes in Women, Review Finds

Worse Stroke Outcomes in Women, Review Finds

Women have worse health-related quality of life and more activity limitations after stroke.

FDA Approves Expanded Treatment Window for Clot Retrieval Device in Acute Ischemic Stroke

FDA Approves Expanded Treatment Window for Clot Retrieval Device in Acute Ischemic Stroke

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The FDA has expanded the treatment window for a clot retrieval device in certain patients presenting with acute ischemic stroke.

Risk Factors Have Varying Effects on Stroke Pathology

Risk Factors Have Varying Effects on Stroke Pathology

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The results confirm that ischemic, hemorrhagic, and subarachnoid stroke have very different etiologies.

General Anesthesia a Viable Sedation Strategy for Thrombectomy in Stroke: Clinician Takeaway

General Anesthesia a Viable Sedation Strategy for Thrombectomy in Stroke: Clinician Takeaway

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Although several studies have established the use of endovascular therapy with stent retrievers for selected acute stroke as standard of care, best practices surrounding the best sedation strategy remain unclear.

Updated Ischemic Stroke Guidelines: Expert Takeaways

Updated Ischemic Stroke Guidelines: Expert Takeaways

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Under the new ischemic stroke guidelines, the treatment window for thrombectomy has been expanded to up to 24 hours after symptom onset.

Stroke Treatment Times May Be Reduced With Pharmacist Involvement

Stroke Treatment Times May Be Reduced With Pharmacist Involvement

A significantly shorter door-to-needle time is associated with the presence of a pharmacist at bedside during acute ischemic stroke.

Stroke Neurocognitive Outcomes Improved With Gingko Biloba Extract

Stroke Neurocognitive Outcomes Improved With Gingko Biloba Extract

Ginkgo biloba extract along with aspirin alleviates cognitive deficits in acute ischemic stroke.

Signficant Risk of Seizures After Stroke Treatment With Reperfusion Therapies

Signficant Risk of Seizures After Stroke Treatment With Reperfusion Therapies

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Patients undergoing treatment for ischemic stroke are at greater risk for seizure development.

Stroke Associated With Long-Term Brain Effects, Accelerated Functional Decline

Stroke Associated With Long-Term Brain Effects, Accelerated Functional Decline

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The effects of ischemic stroke on disability trajectories over an extended period of time were examined.

No Clear Benefit for Early Statin Therapy in Acute Ischemic Stroke

No Clear Benefit for Early Statin Therapy in Acute Ischemic Stroke

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Patients enrolled in this study had strokes that were mild in severity, reducing the generalizability of these findings to the broader population.

Combination Treatment Reduces Ischemic Stroke Risk in Acute Coronary Syndrome

Combination Treatment Reduces Ischemic Stroke Risk in Acute Coronary Syndrome

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Patients who experience acute coronary syndrome are at greater risk of recurrent ischemic events, including stroke.

Reperfused Penumbral Volume Predicts Outcomes in Acute Ischemic Stroke

Reperfused Penumbral Volume Predicts Outcomes in Acute Ischemic Stroke

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All patients included in the study underwent a MRI or multimodal CT approximately 24 hours after onset of stroke.

Ischemic Stroke Risk Increased With Protein Pump Inhibitor Use

Ischemic Stroke Risk Increased With Protein Pump Inhibitor Use

Long-term, high-dose usage of PPIs increases the risk of first-time ischemic stroke and myocardial infarction.

ENCHANTED Update: No Role for Low-Dose Alteplase After All?

ENCHANTED Update: No Role for Low-Dose Alteplase After All?

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Results from a secondary analysis of the ENCHANTED trial add to a pile of weak data that likely will not affect clinical practice.

Stroke Severity, Collateral Blood Flow Indicate ASPECTS Decay

Stroke Severity, Collateral Blood Flow Indicate ASPECTS Decay

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Significant infarct progression can make patients ineligible for mechanical thrombectomy.

After Stroke, High-Intensity Statin Therapy Linked to Fewer Adverse Events

After Stroke, High-Intensity Statin Therapy Linked to Fewer Adverse Events

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The findings support the continuation of high-intensity statin therapy after acute ischemic stroke.

High-Risk Stroke Patients With Insulin Resistance Benefit More From Pioglitazone

High-Risk Stroke Patients With Insulin Resistance Benefit More From Pioglitazone

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Insulin-resistant patients with ischemic stroke or transient ischemic attack and a high risk of myocardial infarction or recurrent stroke are more likely to derive benefit from pioglitazone than those a lower risk.

Thromboembolic Events Most Frequent Mechanism in Postoperative Ischemic Stroke

Thromboembolic Events Most Frequent Mechanism in Postoperative Ischemic Stroke

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A better understanding of characteristics of cerebral lesions may help expedite treatment and improve functional outcomes.

Rivaroxaban, Warfarin Show Similar Efficacy in AFib-Related Ischemic Stroke

Rivaroxaban, Warfarin Show Similar Efficacy in AFib-Related Ischemic Stroke

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The investigators noted that rivaroxaban was associated with significantly reduced length of hospital stay compared with warfarin.

Intravenous Thrombolysis Plus Mechanical Thrombectomy Improves Stroke Outcomes

Intravenous Thrombolysis Plus Mechanical Thrombectomy Improves Stroke Outcomes

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The findings align with current guidelines to administer IV tPA regardless of whether or not a patient with ischemic stroke is set to undergo mechanical thrombectomy.

Predicting Cerebral Edema Severity After Stroke

Predicting Cerebral Edema Severity After Stroke

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There is some evidence that suggests intravenous thrombolysis for stroke may impair the blood-brain barrier and cause cerebral edema.

No Benefit of Contact Aspiration Over Stent Retriever in Ischemic Stroke

No Benefit of Contact Aspiration Over Stent Retriever in Ischemic Stroke

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The findings may be less applicable to low-volume stroke centers who have less experience in this treatment.

Adult Ischemic Stroke Associated With Higher Childhood BMI

Adult Ischemic Stroke Associated With Higher Childhood BMI

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Investigators found a positive association between higher childhood BMI scores and early adult ischemic stroke.

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