Investigators explored the use of serum neurofilament light chain as a biomarker for primary and secondary neuroaxonal injury after ischemic stroke.
Alteplase may increase the risk for symptomatic intracranial hemorrhage vs aspirin.
More adhesive-type interactions were observed between the thrombus and stent-retriever after thrombectomy in patients with acute ischemic stroke.
For patients with ischemic stroke with an unknown time of onset, intravenous alteplase is associated with better functional outcome than placebo.
Congenital Heart Disease, Hispanic Ethnicity Associated With Increased Mortality in Pediatric Arterial Ischemic StrokeMay 21, 2018
The investigators were unable to determine which type of congenital heart disease or which type of ventricular assist device, if used, played a role in mortality outcomes.
The findings from this trial are limited to only ischemic stroke patients with large-vessel occlusion who are deemed appropriate for thrombolysis.
There were no differences between the ceftriaxone and standard care groups in terms of institutional care resources, out-of-pocket expenses, or productivity losses.
Sickle cell trait is not associated with ischemic stroke and should not be relied upon as a sole predictor of stroke in African Americans.
The lack of a comparator group as well as the relatively small patient sample represents potential limitations of this study.
Variations in reperfusion rates as well as MRI assessments among included studies represent possible limitations of this meta-analysis.
The results suggest a noninvasive method for predicting individualized risk for certain stroke subtypes.
Women have worse health-related quality of life and more activity limitations after stroke.
The FDA has expanded the treatment window for a clot retrieval device in certain patients presenting with acute ischemic stroke.
The results confirm that ischemic, hemorrhagic, and subarachnoid stroke have very different etiologies.
Although several studies have established the use of endovascular therapy with stent retrievers for selected acute stroke as standard of care, best practices surrounding the best sedation strategy remain unclear.
Under the new ischemic stroke guidelines, the treatment window for thrombectomy has been expanded to up to 24 hours after symptom onset.
A significantly shorter door-to-needle time is associated with the presence of a pharmacist at bedside during acute ischemic stroke.
Ginkgo biloba extract along with aspirin alleviates cognitive deficits in acute ischemic stroke.
The effects of ischemic stroke on disability trajectories over an extended period of time were examined.
Patients enrolled in this study had strokes that were mild in severity, reducing the generalizability of these findings to the broader population.
Patients who experience acute coronary syndrome are at greater risk of recurrent ischemic events, including stroke.
All patients included in the study underwent a MRI or multimodal CT approximately 24 hours after onset of stroke.
Long-term, high-dose usage of PPIs increases the risk of first-time ischemic stroke and myocardial infarction.
Results from a secondary analysis of the ENCHANTED trial add to a pile of weak data that likely will not affect clinical practice.
Significant infarct progression can make patients ineligible for mechanical thrombectomy.
The findings support the continuation of high-intensity statin therapy after acute ischemic stroke.
Insulin-resistant patients with ischemic stroke or transient ischemic attack and a high risk of myocardial infarction or recurrent stroke are more likely to derive benefit from pioglitazone than those a lower risk.
A better understanding of characteristics of cerebral lesions may help expedite treatment and improve functional outcomes.
The investigators noted that rivaroxaban was associated with significantly reduced length of hospital stay compared with warfarin.
The findings align with current guidelines to administer IV tPA regardless of whether or not a patient with ischemic stroke is set to undergo mechanical thrombectomy.
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