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LOTRISONE
Skin infections (topicals)
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Drug Name:

LOTRISONE Rx

Generic Name and Formulations:
Betamethasone (as dipropionate) 0.05%, clotrimazole 1%; crm; lotion.

Company:
Merck & Co., Inc.

Therapeutic Use:

Indications for LOTRISONE:

Tinea pedis, t. cruris, t. corporis.

Adult:

T. cruris, t. corporis: apply thin film twice daily for 1 week; max 2 weeks. T. pedis: apply sufficient amount twice daily for 2 weeks; max 4 weeks. Max 45g (crm), 45mL (lotion) per week. Do not occlude.

Children:

<17yrs: not recommended.

Warnings/Precautions:

Avoid eyes. Do not use for diaper dermatitis. Risk of HPA axis suppression with high-potency steroids, prolonged use, application to large surface area, use of occlusive dressings, altered skin barrier, liver failure, young age; discontinue gradually, or reduce dose or potency if occurs. Increased risk of posterior subcapsular cataracts and glaucoma; monitor for visual symptoms. Thinning skin. Reevaluate periodically. Pregnancy (Cat.C). Nursing mothers.

Pharmacological Class:

Steroid + azole antifungal.

Adverse Reactions:

Rash, edema, secondary infections; HPA axis suppression (esp. in children), skin atrophy.

How Supplied:

Crm—15g, 45g; Lotion—30mL

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