Peripheral Nerve Stimulation Reduces Pain, Frequency of Chronic Headache

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Peripheral Nerve Stimulation Reduces Pain, Frequency of Chronic Headache
Peripheral Nerve Stimulation Reduces Pain, Frequency of Chronic Headache

Peripheral nerve stimulation (PNS) is an effective long-term treatment for managing chronic intractable headaches, suggests research published in Pain Physician.

In this retrospective study, PNS reduced mean headache severity on the 11-point Numeric Rating Schedule (NRS) by nearly 50% within one-month post implantation. After 12 months, headache severity scores decreased by at least 50% in 87% (40 of 46) of the patients, with pain decreasing even more substantially the longer the device was in place. Pain intensity scores on the NRS had decreased by 68% as many as 98 months post-implantation.

These findings were consistent with previous studies; however, this study looked for a response rate of ≥ 50% rather than any improvement. This difference in study design may account for higher responses in previous studies.

“Despite long histories of chronic headaches, the majority of patients had significant reductions in pain scores and the number of headache days per month,” wrote study researcher Billy K. Huh, MD, PhD, of the MD Anderson Cancer Center Department of Pain Medicine in Houston, Texas, and colleagues.

Clinical Chart: Migraine and Headache Treatments

There was no correlation between the effectiveness of the treatment and the number of years the patients had suffered from headaches, they found.

Huh and colleagues reviewed medical records from 46 patients who had been permanently implanted with PNS from January 2005 to January 2012. Patient records and phone interviews were used to measure pain intensity levels, the number of days per month that patients had headaches, and overall patient satisfaction.

Pain scores on the NRS decreased from 7.60 ± 1.73 before implantation to 3.78 ± 2.41 at one month post-implantation, and to 3.32 ± 2.67 at 6 months, 3.42 ± 2.74 at 12 months, and 2.04 ± 2.27 at greater than 12 months (19-98) after implantation (P < .001 for all). The number of headache days per month decreased by about 14 from baseline.

Overall, 83% of patients indicated they were willing to recommend PNS to a friend or family member, 74.4% reported overall satisfaction, and the average treatment satisfaction score was 7.63 on an 11-point scale, which the researchers called “remarkable.”

In descending order, the reasons for patient dissatisfaction were the cost of the procedure, device malfunction, and unmet expectations. However, the researchers concluded that PNS can offer long-term benefits for patients with intractable headaches, and should be considered a viable treatment option.

Reference

  1. Lee PB, Horazeck C, Nahm FS, Huh BK. Peripheral Nerve Stimulation for the Treatment of Chronic Intractable Headaches: Long-term Efficacy and Safety Study. Pain Physician. 2015;18:505-516.
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