Migraine And Headache

Comorbidity More Likely With Chronic Migraine vs Episodic Migraine

Comorbidity More Likely With Chronic Migraine vs Episodic Migraine

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Researchers deployed a survey to determine the extent of pain, psychiatric, endocrine, and neurologic comorbidities in patients with chronic or episodic migraine.

Eptinezumab for Frequent Episodic Migraine: Results of Phase 3 PROMISE-1 Study

Eptinezumab for Frequent Episodic Migraine: Results of Phase 3 PROMISE-1 Study

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Eptinezumab, a humanized monoclonal antibody specific to calcitonin gene-related peptide, may be an effective prophylactic for individuals with frequent episodic migraines.

Patient Develops Thunderclap Headaches After Consuming 'Carolina Reaper'

Patient Develops Thunderclap Headaches After Consuming 'Carolina Reaper'

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The authors note that this appears to be the first case of RCVS secondary to pepper or cayenne ingestion.

Noninvasive Brain Stimulation May Help Prevent Migraines

Noninvasive Brain Stimulation May Help Prevent Migraines

Single-pulse transcranial magnetic stimulation device is safe and easy to use.

Novel Nasal Spray for Migraine Attacks to Be FDA Reviewed

Novel Nasal Spray for Migraine Attacks to Be FDA Reviewed

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DFN-02 was evaluated in a multicenter, double-blind, randomized, placebo-controlled study (N=107) which showed it was effective in treating pain and associated symptoms during a migraine attack and in reducing attack-related functional disability.

Sumatriptan Self-Injection System No Longer Available

Sumatriptan Self-Injection System No Longer Available

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Sumavel DosePro for the treatment of migraine or cluster headache has been discontinued.

Erenumab for Episodic Migraine: A Closer Look at the Data

Erenumab for Episodic Migraine: A Closer Look at the Data

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For individuals with migraine frequency of 4 to 14 episodes per month, prophylactic medications and analgesics are required.

Ubrogepant Effective for Acute Migraine Relief

Ubrogepant Effective for Acute Migraine Relief

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Allergan has reported positive results from the first of 2 Phase 3 trials for ubrogepant for the treatment of migraine.

GammaCore Approved for Treatment of Acute Migraine Pain

GammaCore Approved for Treatment of Acute Migraine Pain

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The FDA has granted GammaCore 510(k) expanded clearance to treat migraine related pain.

Refractory Migraine Effectively Treated With Erenumab

Refractory Migraine Effectively Treated With Erenumab

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Amgen announced that erenumab met its primary endpoint in reducing monthly migraine days.

Migraine, Tension-Type Headache Likely After Exposure to Violence

Migraine, Tension-Type Headache Likely After Exposure to Violence

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Prior physical or sexual abuse of survivors increased the likelihood of migraine or tension-type headache.

Coping Questionnaire Helps Assess Migraine Pain

Coping Questionnaire Helps Assess Migraine Pain

The PSEQ successfully shows the debility in migraine surgery patients, and puts migraine pain to perspective.

Migraine Risk Significantly Reduced With Investigational Drug

Migraine Risk Significantly Reduced With Investigational Drug

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Patients were randomly assigned to receive eptinezumab (300mg or 100mg) or placebo once every 12 weeks.

Early Treatment, Milder Migraine Symptoms Linked to Improved Outcomes With OnabotulinumtoxinA

Early Treatment, Milder Migraine Symptoms Linked to Improved Outcomes With OnabotulinumtoxinA

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For patients with chronic migraine, onabotulinumtoxinA was shown to have a better outcome.

Migraine Resolves With Antiviral, NSAID Drug Combo: Case Report

Migraine Resolves With Antiviral, NSAID Drug Combo: Case Report

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In a case report, a 21 year old female's migraine was successfully treated with therapy specifically aimed at the herpes simplex virus.

Weight Loss, Migraine Education Have Similar Effect on Migraine Reduction

Weight Loss, Migraine Education Have Similar Effect on Migraine Reduction

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Researchers report that a behavioral weight loss program may be effective in reducing migraine headaches as social support from a group of people facing similar circumstances may help patients cope.

Caffeine as Headache Trigger and Treatment: Two Sides of the Same Coin

Caffeine as Headache Trigger and Treatment: Two Sides of the Same Coin

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The judicious use of caffeine as adjuvant therapy to over-the-counter pain relievers can improve or relieve pain for patients with migraine or tension-type headaches.

Reducing Stroke Risk in Women With Migraine Receiving Hormonal Contraceptives: Consensus Statement

Reducing Stroke Risk in Women With Migraine Receiving Hormonal Contraceptives: Consensus Statement

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Women with migraine should avoid high-risk products such as combined oral HCs consisting of >35μg ethinylestradiol.

FDA Will Review Injectable Migraine Prevention Treatment

FDA Will Review Injectable Migraine Prevention Treatment

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The FDA has accepted a BLA for the migraine prevention treatment, galcanezumab.

Patients With Migraine Often Return to the Emergency Department

Patients With Migraine Often Return to the Emergency Department

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Over 25% of patients who end up in the emergency department for migraine typically require revisits for headache within 6 months.

Magnesium May Be Effective for Migraine Prophylaxis

Magnesium May Be Effective for Migraine Prophylaxis

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The review suggests that magnesium is a safe, tolerable, and cost-effective treatment for migraine.

Higher Stroke Risk Associated With Estrogen Contraceptives in Women With Migraine

Higher Stroke Risk Associated With Estrogen Contraceptives in Women With Migraine

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A systematic review aimed to validate whether stroke risk is increased in women taking estrogen-containing contraceptives who have a history of migraine.

Devices for Acute, Preventive Migraine Care Now Available

Devices for Acute, Preventive Migraine Care Now Available

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Cefaly Acute and Cefaly Dual were approved for treating migraines.

Distinct Clinical Characteristics of Headache Associated With Subarachnoid Hemorrhage

Distinct Clinical Characteristics of Headache Associated With Subarachnoid Hemorrhage

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A study identified distinguishing clinical characteristics of headaches associated with nontraumatic subarachnoid hemorrhage.

Erenumab, Fremanezumab Reduce Migraine Frequency, Burden

Erenumab, Fremanezumab Reduce Migraine Frequency, Burden

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Both erenumab and fremanezumab are currently under review by the FDA for the treatment of migraine.

Exploring Current and Developing Migraine Behavioral Treatments: Expert Q&A

Exploring Current and Developing Migraine Behavioral Treatments: Expert Q&A

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Although pharmacotherapy remains the standard strategy for migraine management, there are many patients for whom nonpharmacological approaches are indicated.

Parkinson Disease Onset Associated With Reductions in Migraine Frequency, Severity

Parkinson Disease Onset Associated With Reductions in Migraine Frequency, Severity

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Patients with Parkinson disease had reductions in the intensity, frequency and overall severity of their headaches and migraines.

Episodic Migraine Increases Risk for CVD, Subsequent Contraindications to Therapy

Episodic Migraine Increases Risk for CVD, Subsequent Contraindications to Therapy

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Clinicians need to consider treatments for episodic migraine that may be contraindicated if a patient also has cardiovascular disease.

Predicting Poor Outcomes in Pediatric Headache With Rapid Screening Tool

Predicting Poor Outcomes in Pediatric Headache With Rapid Screening Tool

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The rapid screening tool may help to inform treatment decisions for at-risk patients.

Frequency of Migraine Associated With Depression, Anxiety

Frequency of Migraine Associated With Depression, Anxiety

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Frequency of migraine with or without aura may be correlated with symptoms of anxiety and depression.

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