Myasthenia Gravis

Belimumab Nonsuperior to Placebo for Reducing Symptoms of Myasthenia Gravis

Belimumab Nonsuperior to Placebo for Reducing Symptoms of Myasthenia Gravis

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The investigators suggest that the recruited participants may have reached a plateau in symptoms, which may have decreased the chances of additional improvement with belimumab treatment.

Firdapse NDA Submitted for Lambert-Eaton Myasthenic Syndrome

Firdapse NDA Submitted for Lambert-Eaton Myasthenic Syndrome

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Results from the Phase 3 trial showed that the Quantitative Myasthenia Gravis (QMG) score at baseline to day 14 changed from 6.4 to 6.7 in the amifampridine group vs. 5.6 to 7.9 for the placebo group.

Myasthenia Gravis Impairment Index Indicates Response to Prednisone, IVIg, PLEX

Myasthenia Gravis Impairment Index Indicates Response to Prednisone, IVIg, PLEX

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The Myasthenia Gravis Impairment Index was developed to incorporate patient input at different stages of disease progression.

Eculizumab Safe, Tolerable for Refractory Generalized Myasthenia Gravis

Eculizumab Safe, Tolerable for Refractory Generalized Myasthenia Gravis

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Treatment with eculizumab was associated with a significant benefit on quality of life.

FDA Approves Myasthenia Gravis Treatment

FDA Approves Myasthenia Gravis Treatment

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The FDA has approved Soliris for treating adults with myasthenia gravis.

Rituximab Improves Outcomes in Patients With Anti-MuSK Myasthenia Gravis

Rituximab Improves Outcomes in Patients With Anti-MuSK Myasthenia Gravis

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Patients with anti-muscle-specific kinase myasthenia gravis typically have a more severe disease presentation, with early bulbar, neck, and respiratory muscle weakness.

Alexion Seeking New Indication for Myasthenia Gravis Drug

Alexion Seeking New Indication for Myasthenia Gravis Drug

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Soliris is currently approved to treat paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).

Rituximab Offers Hope for Refractory Myasthenia Gravis

Rituximab Offers Hope for Refractory Myasthenia Gravis

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Sixty-three percent of patients achieved a complete and stable response that allowed them to discontinue all immunotherapies.

Thymectomy Helps Improve Strength in Myasthenia Gravis

Thymectomy Helps Improve Strength in Myasthenia Gravis

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Patients who underwent surgery also experienced lower distress levels from treatment-related symptoms.

Consensus Guidelines for the Treatment of Myasthenia Gravis

Consensus Guidelines for the Treatment of Myasthenia Gravis

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The guidelines are the result of a consensus of an international task force of MG experts.

Stem Cell Transplant May Promote Remission in Myasthenia Gravis

Stem Cell Transplant May Promote Remission in Myasthenia Gravis

Treatment has been linked to durable, symptom-free, treatment-free remission in several cases of MG.

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