Neurocognitive Disorders

Latest

High CSF Neurogranin Associated With Faster Decline in Mild Cognitive Impairment

High CSF Neurogranin Associated With Faster Decline in Mild Cognitive Impairment

Investigators obtained data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database on patients with normal cognition (n=111) and MCI (n=193), all of whom had CSF Ng samples at baseline as well as memory and executive function evaluations at follow-up.

Retinopathy Associated With Greater Risk for 20-Year Cognitive Decline

Retinopathy Associated With Greater Risk for 20-Year Cognitive Decline

Retinopathy as well as an overall loss of vascular integrity was significantly associated with a greater 20-year cognitive decline after controlling for attrition.

Strategies for Preventing and Treating Delirium

Strategies for Preventing and Treating Delirium

Delirium prevention and the use of nonpharmacologic methods for its treatment may improve short- and long-term outcomes among hospitalized patients.

High Total Cholesterol Neuroprotective Against Cognitive Decline

High Total Cholesterol Neuroprotective Against Cognitive Decline

For older adults with high cholesterol, the risk for cognitive decline is reduced.

Successful Delirium Prevention in Critically Ill With Dexmedetomidine

Successful Delirium Prevention in Critically Ill With Dexmedetomidine

Low-dose dexmedetomidine reduces delirium in critically ill adults.

Cognition Influenced by Cardiorespiratory Fitness, White Matter Integrity

Cognition Influenced by Cardiorespiratory Fitness, White Matter Integrity

In patients with mild cognitive impairment, CRF is associated with better white matter fiber integrity.

Cognitive Deficits Apparent in Pediatric Chronic Kidney Disease

Cognitive Deficits Apparent in Pediatric Chronic Kidney Disease

Children with chronic kidney disease may have deficits in global and domain-specific cognition.

Delirium Treatment Has No Benefit for Survival in Critically Ill

Delirium Treatment Has No Benefit for Survival in Critically Ill

Compared with placebo, prophylactic haloperidol does not improve survival for critically ill adults at high risk of delirium.

Cognitive Decline in Men Linked to Low Serum Sodium

Cognitive Decline in Men Linked to Low Serum Sodium

For community-dwelling older men, low serum sodium is associated with cognitive impairment and cognitive decline.

Factors Predictive of Mild Cognitive Impairment in Healthy Individuals

Factors Predictive of Mild Cognitive Impairment in Healthy Individuals

Investigators sought to examine factors that influence a cognitively normal individual's risk for developing symptoms of mild cognitive impairment due to Alzheimer disease.

Sign Up for Free e-newsletters

CME Focus