The results highlight the importance of evaluating and monitoring cognitive function in individuals with recent critical illness or major infections, especially if they are already at risk for dementia.
The mean duration of dementia was longer among individuals with hippocampal sclerosis vs those without.
Hearing loss affects more than 50% of Americans 60 years or older.
Investigators analyzed the diagnostic performance of plasma cerebrospinal fluid and neurofilament light biomarkers in patients with Down syndrome and Alzheimer disease.
Investigators examined the onset, sequence, and rate of progression of biomarker and clinical measures across the spectrum of Alzheimer disease, using the Dominantly Inherited Alzheimer Network study.
The use of positron emission tomography was able to discriminate between Alzheimer disease and other neurodegenerative disorders in a multicenter, cross-sectional study conducted at 3 dementia centers in South Korea, Sweden, and the United States.
Dementia is associated with mortality in most older adults with Down syndrome.
Investigators examined the effect smoking has on the risk for dementia using a nationwide health claims database in Korea.
Fluorine 18 fluorodeoxyglucose PET of the brain can be used to develop a deep learning algorithm for early prediction of AD that has high specificity and sensitivity.
Individuals with Alzheimer disease have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signaling pathway.
Approximately 5.5 million Americans have Alzheimer disease or dementia.
Preeclampsia seems to be associated with an increased risk for dementia, especially vascular dementia, with a stronger correlation for late-onset disease.
Neurological and neuropsychological examinations were performed to assess intellectual disabilities, and biological assays were performed on collected CSF and plasma.
Grand multiparity was associated with significantly worse Mini-Mental State Examination scores compared with those with 1 to 4 completed pregnancies.
Atrial fibrillation is associated with a faster global cognitive decline and an increased risk for dementia in older people.
Investigators evaluated cognition with measures reflecting executive function, episodic memory, semantic fluency, and processing speed on an annual basis.
There is a positive association between residential levels of air pollution and being diagnosed with dementia.
Age, sex and apolipoprotein E genotype can identify groups at high 10-year risk for Alzheimer disease and all dementia.
Multiple pathways account for the age-related increases in dementia risk.
The burden of Alzheimer disease and related dementias is expected to increase to 3.3% in the United States by 2060.
Retinal microvascular abnormalities are identified in cognitively healthy individuals who have biomarkers positive for Alzheimer disease.
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