Hearing loss affects more than 50% of Americans 60 years or older.
Investigators analyzed the diagnostic performance of plasma cerebrospinal fluid and neurofilament light biomarkers in patients with Down syndrome and Alzheimer disease.
Primary progressive aphasia (PPA) classification system suggests that age and apolipoprotein E genotype should be taken into account when interpreting β biomarkers in PPA.
The use of positron emission tomography was able to discriminate between Alzheimer disease and other neurodegenerative disorders in a multicenter, cross-sectional study conducted at 3 dementia centers in South Korea, Sweden, and the United States.
Dementia is associated with mortality in most older adults with Down syndrome.
Investigators examined the effect smoking has on the risk for dementia using a nationwide health claims database in Korea.
Pre-eclampsia is defined as new onset hypertension accompanied by signs of organ dysfunction in the setting of pregnancy.
Individuals with Alzheimer disease have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signaling pathway.
Approximately 5.5 million Americans have Alzheimer disease or dementia.
The results highlight the importance of evaluating and monitoring cognitive function in individuals with recent critical illness or major infections, especially if they are already at risk for dementia.
Preeclampsia seems to be associated with an increased risk for dementia, especially vascular dementia, with a stronger correlation for late-onset disease.
Neurological and neuropsychological examinations were performed to assess intellectual disabilities, and biological assays were performed on collected CSF and plasma.
Grand multiparity was associated with significantly worse Mini-Mental State Examination scores compared with those with 1 to 4 completed pregnancies.
Tiglutik is supplied as a thickened riluzole liquid that is intended to ease administration for patients with dysphagia.
In multivariable models, associations were observed between cardiovascular risk factors and cerebrovascular morphology, as well as white matter hyperintensity count.
Atrial fibrillation is associated with a faster global cognitive decline and an increased risk for dementia in older people.
In this cross-sectional study, the tau marker [18F]flortaucipir accurately distinguished Alzheimer's Disease dementia from other non-AD neurodegenerative disorders about 90% of the time.
Investigators evaluated cognition with measures reflecting executive function, episodic memory, semantic fluency, and processing speed on an annual basis.
There is a positive association between residential levels of air pollution and being diagnosed with dementia.
Age, sex and apolipoprotein E genotype can identify groups at high 10-year risk for Alzheimer disease and all dementia.
Multiple pathways account for the age-related increases in dementia risk.
The burden of Alzheimer disease and related dementias is expected to increase to 3.3% in the United States by 2060.
Based on the data, the FDA has concluded that the drug's benefit continues to outweigh its risks for patients with hallucinations and delusions associated with Parkinson's disease psychosis.
In this prospective cohort study, older patients with more optimal cardiovascular health metrics had a lower rate of developing dementia in a dose-dependent manner.
Retinal microvascular abnormalities are identified in cognitively healthy individuals who have biomarkers positive for Alzheimer disease.
Pseudobulbar affect is a significant national health issue in the United States, with approximately 2 million individuals affected.
Patients with a higher mean systolic blood pressure during follow-up had increased odds for brain infarcts compared with those with lower levels.
Having high insulin at baseline was associated with a greater risk for incident diabetes mellitus compared with low insulin values.
For older adults, increased numbers of optimal cardiovascular health metrics are associated with reduced risk of dementia.
Administering the Visual Association Test improves the predictive value of the Mini-Mental State Examination score for dementia.
Neurology Advisor Articles
- Surgical, Nonsurgical Treatments for Chronic Migraine: Evidence and Relevancy
- Neurofilament Light Biomarkers Identify Alzheimer Disease Risk in Down Syndrome
- Myoclonic-Atonic Seizures and Lennox-Gastaut Syndrome Present With Overlapping Features, Difficulty in Diagnosis
- Tap Water in Neti Pot Linked to Brain Infection, Death From Balamuthia mandrillaris
- Rituximab Effects in Neuromyelitis Optica Spectrum Disorders
- Study Identifies Early-Onset Motor Behaviors in DES-Triggered Seizures
- Autoimmune Diseases Increase Hippocampal Sclerosis Risk in Nonagenarians
- Smaller Heads Related to Opioid-Related Neonatal Abstinence Syndrome
- Hearing Loss in Older Adults Linked to Depression, Dementia Among Other Comorbidities
- Bumetanide May Benefit Children With Autism Spectrum Disorder