Neuromuscular Disorders Feature Archive

Family Planning in MS: Dispelling Myths and Encouraging Conversations

Family Planning in MS: Dispelling Myths and Encouraging Conversations

Rosalind C. Kalb, PhD, a clinical psychologist, offers her insights on how clinicians can address patient concerns about reproductive issues and MS.

Approaches for Better Diagnosis of Pediatric Multiple Sclerosis

Approaches for Better Diagnosis of Pediatric Multiple Sclerosis

Pediatric MS is predominantly inflammatory in nature, with a presentation that is similar to a number of other conditions.

Comorbidities in Multiple Sclerosis: Effects on DMTs, the Treatment Team, and More

Comorbidities in Multiple Sclerosis: Effects on DMTs, the Treatment Team, and More

Having a higher burden of comorbidities is associated with greater disability progression and lower QoL, as well as increased healthcare utilization and mortality.

Exploring the Benefits of Virtual Reality Rehabilitation in Multiple Sclerosis

Exploring the Benefits of Virtual Reality Rehabilitation in Multiple Sclerosis

Future studies on VR training for MS should include large randomized controlled trials using clear protocols and comparable between-group tasks.

Ethical Challenges of Nusinersen: Considerations When Counseling on Treatment

Ethical Challenges of Nusinersen: Considerations When Counseling on Treatment

Although regarded as a miracle drug to some, nusinersen comes with some troublesome strings attached.

Understanding ICU-Acquired Neuromuscular Dysfunction: Triggers, Risk Factors, and Treatments

Understanding ICU-Acquired Neuromuscular Dysfunction: Triggers, Risk Factors, and Treatments

ICU-acquired weakness syndromes manifest themselves in a range of ways among patients — as a spectrum of disease rather than in specific form.

Primary Periodic Paralysis: Advice for Clinicians & Future Directions

Primary Periodic Paralysis: Advice for Clinicians & Future Directions

Neurology Advisor speaks with Annabelle Baughan, a retired hematologist-oncologist, and discusses her personal experience with Andersen-Tawil syndrome.

Multiple Sclerosis Guidelines: AAN's Recommendations for Initiating, Switching, Stopping Disease-Modifying Therapy

Multiple Sclerosis Guidelines: AAN's Recommendations for Initiating, Switching, Stopping Disease-Modifying Therapy

The new guidelines focus on helping clinicians decide when to initiate, switch, or discontinue disease-modifying therapies for multiple sclerosis.

Primary Periodic Paralysis: A Physician's Personal Experience as a Patient

Primary Periodic Paralysis: A Physician's Personal Experience as a Patient

Neurology Advisor spoke with Annabelle Baughan, a retired hematologist-oncologist, who discussed her personal experience with Andersen-Tawil syndrome.

Genetics May Hold the Key to Decoding Periodic Paralysis

Genetics May Hold the Key to Decoding Periodic Paralysis

The cluster of diagnoses known as periodic paralyses — including hypokalemic periodic paralysis, hyperkalemic periodic paralysis, and Anderson-Tawil syndrome — are rare genetic disorders of spontaneous muscle weakness or paralysis that can last from minutes to days.

Shortcomings in ALS Research: Strategies for Improvement

Shortcomings in ALS Research: Strategies for Improvement

Researchers recently identified 5 key challenges that collectively hinder the design of amyotrophic lateral sclerosis clinical trials and the development of new treatments.

McDonald Criteria Update: Further Distinction Between Relapsing-Remitting, Primary-Progressive MS

McDonald Criteria Update: Further Distinction Between Relapsing-Remitting, Primary-Progressive MS

The 2017 revision takes aim at better differentiating relapsing-remitting and primary-progressive forms of multiple sclerosis.

Ask the Expert: Managing Urinary Retention in Multiple Sclerosis

Ask the Expert: Managing Urinary Retention in Multiple Sclerosis

John Stoffel, MD, Professor of Urology, Service Chief, and Associate Chair for Ambulatory Urology in the University of Michigan Department of Urology discusses the management of urinary retention in patients with MS.

Differentiating Multiple Sclerosis Mimics on MRI

Differentiating Multiple Sclerosis Mimics on MRI

A proper MS diagnosis can only be made after obtaining imaging from the entire brain and understanding the clinical context.

Consensus Guidelines for the Treatment of Myasthenia Gravis

Consensus Guidelines for the Treatment of Myasthenia Gravis

The guidelines are the result of a consensus of an international task force of MG experts.

Managing Bladder Dysfunction in Multiple Sclerosis

Managing Bladder Dysfunction in Multiple Sclerosis

One of the biggest hurdles is getting the patient to be honest and open with you about bladder problems.

Duchenne Muscular Dystrophy Update: FDA Weighs Its Options

Duchenne Muscular Dystrophy Update: FDA Weighs Its Options

The DMD space is becoming increasingly crowded as the FDA works to identify a drug worth approving.

What to Expect at CMSC 2016

What to Expect at CMSC 2016

Neurology Advisor reviews the upcoming agenda for the CMSC annual meeting.

Epilepsy Drug May Be Neuroprotective in Optic Neuritis

Epilepsy Drug May Be Neuroprotective in Optic Neuritis

Those treated with phenytoin saw a 30% reduction in retinal nerve fiber loss.

Beyond First-Line: Natalizumab vs Fingolimod for Relapsing-Remitting Multiple Sclerosis

Beyond First-Line: Natalizumab vs Fingolimod for Relapsing-Remitting Multiple Sclerosis

When first-line therapies fail, physicians must consider several factors when choosing the next course of treatment for their RRMS patients.

Can We Vaccinate Against PML in Multiple Sclerosis?

Can We Vaccinate Against PML in Multiple Sclerosis?

Antibodies in the CSF may be able to seek out and eliminate JC polyomavirus variants.

Exercise Benefits Mental, Physical Well-Being in Multiple Sclerosis

Exercise Benefits Mental, Physical Well-Being in Multiple Sclerosis

Exercise and general increases in daily physical activity can help improve balance, reduce fatigue, and regain mental clarity in patients with MS.

Addressing Depression, Anxiety, and Fatigue in Multiple Sclerosis

Addressing Depression, Anxiety, and Fatigue in Multiple Sclerosis

The most recognized symptom of MS is fatigue, a hard to treat comorbidity that can manifest into other conditions.

Vitamin D as a Neuroprotective Agent for Amyotrophic Lateral Sclerosis

Vitamin D as a Neuroprotective Agent for Amyotrophic Lateral Sclerosis

Vitamin D deficiency is known to contribute to neurodegenerative diseases like dementia, however its connection to ALS is not yet well understood.

Emerging Technologies for Monitoring Multiple Sclerosis

Emerging Technologies for Monitoring Multiple Sclerosis

Advanced imaging technologies to monitor multiple sclerosis (MS) are being developed but have been plagued by high costs and invasive procedures.

Oral Therapies Come of Age for Multiple Sclerosis

Oral Therapies Come of Age for Multiple Sclerosis

The advent of oral therapy now gives multiple sclerosis patients more options besides injections, which were the mainstay treatment.

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