Neuromuscular Disorders

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Primary Periodic Paralysis: A Physician's Personal Experience as a Patient

Primary Periodic Paralysis: A Physician's Personal Experience as a Patient

Neurology Advisor spoke with Annabelle Baughan, a retired hematologist-oncologist, who shared her personal experience with Andersen-Tawil syndrome.

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AAN: High Fish Intake Linked to Reduced Risk of Multiple Sclerosis

AAN: High Fish Intake Linked to Reduced Risk of Multiple Sclerosis

Compared with consuming fish less than once per month and no supplements, high fish intake was correlated with a significantly reduced risk of multiple sclerosis.

Scoliosis Surgery Found Beneficial for Cerebral Palsy Patients

Scoliosis Surgery Found Beneficial for Cerebral Palsy Patients

Scoliosis surgery in patients with cerebral palsy leads to a significant improvement in health-related quality of life.

Fingolimod May Help Prevent Brain Volume Loss in Relapsing-Remitting Multiple Sclerosis

Fingolimod May Help Prevent Brain Volume Loss in Relapsing-Remitting Multiple Sclerosis

Participants who were treated with both doses of fingolimod experienced less overall progression of disability than those receiving placebo.

Pinpointing Clinically Meaningful Change in Cervical Dystonia Treated With Botulinum Toxin

Pinpointing Clinically Meaningful Change in Cervical Dystonia Treated With Botulinum Toxin

The administration of treatment was performed over 5 treatment cycles, and the investigators assessed TWSTRS changes at baseline and 4 weeks following injection.

Firdapse NDA Submitted for Lambert-Eaton Myasthenic Syndrome

Firdapse NDA Submitted for Lambert-Eaton Myasthenic Syndrome

Results from the Phase 3 trial showed that the Quantitative Myasthenia Gravis (QMG) score at baseline to day 14 changed from 6.4 to 6.7 in the amifampridine group vs. 5.6 to 7.9 for the placebo group.

Primary Periodic Paralysis: A Physician's Personal Experience as a Patient

Primary Periodic Paralysis: A Physician's Personal Experience as a Patient

Neurology Advisor spoke with Annabelle Baughan, a retired hematologist-oncologist, who shared her personal experience with Andersen-Tawil syndrome.

First-in-Class Inhibitor Designated Orphan Drug for Spinal Muscular Atrophy

First-in-Class Inhibitor Designated Orphan Drug for Spinal Muscular Atrophy

By inhibiting the activation of myostatin, SRK-015 may promote a clinically meaningful increase in muscle mass and strength.

Improvement in Acute Optic Neuritis Similar With IV, Oral Corticosteroids

Improvement in Acute Optic Neuritis Similar With IV, Oral Corticosteroids

The advantages of oral prednisone include "being less expensive and more convenient to access and administer and [being] preferred by patients to [intravenous] methylprednisolone."

DMT Discontinuation in Older MS Patients: Clinical Outcomes Examined

DMT Discontinuation in Older MS Patients: Clinical Outcomes Examined

Of the total patients, 178 (29.7%) discontinued DMT during the study period with only 1 documented relapse occurring in the discontinuers.

Siponimod Reduces Disability Progression in Secondary Progressive Multiple Sclerosis

Siponimod Reduces Disability Progression in Secondary Progressive Multiple Sclerosis

Further research should focus on establishing whether siponimod exerts its effect on the pathogenic processes associated with disease progression or activity, or both.

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