Neuro-oncology

Cognitive Impairment Not Common Post-Skull Radiation

Cognitive Impairment Not Common Post-Skull Radiation

Most patients undergoing skull base irradiation for cancer do not have detectable cognitive impairment.

Postoperative Stereotactic Radiosurgery Reduces Recurrence After Metastases Resection

Postoperative Stereotactic Radiosurgery Reduces Recurrence After Metastases Resection

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The use of postoperative stereotactic radiosurgery could be a substitute for whole-brain radiotherapy, which has been linked to cognitive adverse effects.

Brain Tumor Histology and Incidence in Adolescents and Young Adults

Brain Tumor Histology and Incidence in Adolescents and Young Adults

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Over 10 000 brain and CNS tumors are diagnosed in adolescent and young adults each year.

Electromagnetic Field Therapy Promising for Glioblastoma Treatment

Electromagnetic Field Therapy Promising for Glioblastoma Treatment

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Two years post-enrollment, 43% of patients in the combination therapy group were alive.

Anthracycline-Based Chemo Affects Cognition, Brain Connectivity

Anthracycline-Based Chemo Affects Cognition, Brain Connectivity

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Anthracycline-based chemotherapy was associated with worse cognitive outcomes than nonanthracycline chemo.

VIDEO: Global Coalition to Design Adaptive Clinical Trial for Glioblastoma

VIDEO: Global Coalition to Design Adaptive Clinical Trial for Glioblastoma

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The adaptive trial design will allow GBM patients to benefit from precision medicine.

DNA From Cerebrospinal Fluid May Effectively Monitor Brain Metastases

DNA From Cerebrospinal Fluid May Effectively Monitor Brain Metastases

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Researchers found that brain tumor mutations could be detected from ctDNA in cerebrospinal fluid.

Training Sessions Improve Cognition in Pediatric Cancer Survivors

Training Sessions Improve Cognition in Pediatric Cancer Survivors

The training sessions improved measures of working memory, attention, and processing speed.

Chemotherapy-Induced Peripheral Neuropathy Common, but Underdiagnosed

Chemotherapy-Induced Peripheral Neuropathy Common, but Underdiagnosed

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As many as 50% of neurotoxic chemotherapy patients experience CPN.

Chemoradiation for Glioblastoma Reduces Brain Volume

Chemoradiation for Glioblastoma Reduces Brain Volume

A reduction primarily in grey matter and expansion of the brain's ventricles was observed.

Trends in Glioma Treatment Show Increased Survival Rates

Trends in Glioma Treatment Show Increased Survival Rates

Researchers found a decrease in use of radiation treatment after 2005.

Glioma Subtypes Identified Through Genomic Alterations

Glioma Subtypes Identified Through Genomic Alterations

Two studies classified gliomas into distinct subtypes by analyzing their genomes.

Anticoagulation Safe for Patients with Brain Metastases

Anticoagulation Safe for Patients with Brain Metastases

Treatment does not cause significant increase in incidence of intracranial hemorrhage

Targeted Radiation Preserves Cognition in Brain Metastases Tx

Targeted Radiation Preserves Cognition in Brain Metastases Tx

Survival rates were similar for both methods, but targeted radiation helped preserve cognition.

Growing Number of Cancer Patients Interested in Genetic Profiling

Growing Number of Cancer Patients Interested in Genetic Profiling

Many are willing to pay out of pocket for the test.

IBM's Watson Helps Generate Personalized Cancer Treatment Plans

IBM's Watson Helps Generate Personalized Cancer Treatment Plans

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Watson can analyze and interpret genetic data in minutes — a process that normally takes physicians weeks to complete.

Epigenetic Drug May Help Inhibit Growth of Pediatric Glioma

Epigenetic Drug May Help Inhibit Growth of Pediatric Glioma

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The combination of two histone inhibitors seemed to slow DIPG cell growth even further.

Chemo Brain is Real and Affects Ability to Concentrate

Chemo Brain is Real and Affects Ability to Concentrate

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The ability to focus and maintain concentration seems to be directly affected in "chemo brain."

Brain and Spine Findings Require More Pediatrician Awareness

Brain and Spine Findings Require More Pediatrician Awareness

Great awareness among pediatricians will allow them to better counsel concerned parents and make referrals to subspecialists.

Inhibition of Enzyme GLDC Could Kill Off Glioblastoma Cells

Inhibition of Enzyme GLDC Could Kill Off Glioblastoma Cells

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Researchers also found mechanisms of cell survival in ischemic regions of brain tumor.

2011 CDC Estimates of Cancer Incidence, Survival

2011 CDC Estimates of Cancer Incidence, Survival

On average, 65% of cancer patients survived after a period of 5 years, but survival was lower among black people.

Gene Variant May Increase Neuropathy Risk in Pediatric Leukemia Drug

Gene Variant May Increase Neuropathy Risk in Pediatric Leukemia Drug

Patients with ALL who have a variant of gene CEP72 may experience more frequent and severe neuropathy while on vincristine.

Chemotherapy Slows Glioma Progression After Radiation

Chemotherapy Slows Glioma Progression After Radiation

Procarbazine, CCNU, and vincristine administered after radiation therapy was shown to improve survival in gliomas.

Brittany Maynard's 'Death with Dignity' Poses Challenge to Hippocratic Oath

Brittany Maynard's 'Death with Dignity' Poses Challenge to Hippocratic Oath

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Brittany Maynard's physician-assisted suicide has reignited the "death with dignity" debate that challenges the ethical standards of the medical profession.

Cancer Patients at Risk of Mental Health Disorders

Cancer Patients at Risk of Mental Health Disorders

Patients with breast cancer, head and neck cancer and malignant melanoma particularly are at risk of developing a mental health disorder, a new study shows.

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