As part of the REMS program, drug companies with approved opioid analgesics must make training available to prescribers and provide unrestricted grants to accredited continuing education providers for the development of education courses.
Many outpatient opioid prescriptions have no documented medical indication.
Purdue Pharma, the maker of Oxycontin who some have blamed for the epidemic of opioid painkiller addictions, has patented a medicine aimed at curbing those disorders.
Among surgical patients who develop new persistent opioid use, surgeons provide the majority of opioid prescriptions in the first few months after surgery.
A $3.4 million grant to help a non-profit company develop a less expensive opioid overdose antidote was announced by Purdue Pharma, which makes the opioid painkiller OxyContin.
Patients coprescribed opioids and pregabalin had significantly increased odds of opioid-related death compared to opioid prescription alone.
The new plan will break out the current guidance into 4 separate guidances.
Rates of opioid use in the United States do not appear to be declining.
Four more online networks that operate 21 websites illegally selling potentially dangerous, unapproved, and misbranded versions of opioid pain medications have been told to immediately stop their sales.
Concomitant exposure to pregabalin and opioids is associated with increased odds of opioid-related death.
Last year, the DEA proposed a 20% reduction in the manufacturing of controlled substances for 2018 compared to 2017.
Children often fill outpatient opioid prescriptions, with the most common indication for dental procedures.
A novel, innovative initiative is being developed to help end addiction over the long term.
Use of medications for opioid use disorder is associated with a reduction in all-cause and opioid-related mortality after opioid overdose.
The US Drug Enforcement Administration's 2014 ruling to reschedule hydrocodone combination products coincided with an increase in illicit trading of opioids through online illicit markets.
Nine online networks have been warned that they must stop illegally marketing potentially dangerous, and misbranded versions of opioid medications.
A recall of the opioid overdose antidote Naloxone was announced Monday.
A NDA has been submitted for NKTR-181, an opioid analgesic molecule designed to provide pain relief with fewer CNS-mediated side effects.
Evidence on whether the implementation of prescription drug monitory programs increases or decreases opioid-related overdoses was found to be "largely insufficient".
Investigators conducted a population-based study to assess risk and cause of unnatural mortality in individuals with epilepsy.
Higher education, illicit drug use, depression, and pain interference with normal work are significantly associated with opioid misuse.
Another case of unusual amnestic syndrome that includes bilateral hippocampal lesions on MRI has been described.
Disposal of unused opioids after surgery is improved with an educational brochure.
The authors examined the demographic and geographic variation and the correlation between the local economic environment and measures of individual opioid prescriptions.
Higher-concentration intranasal naloxone has similar efficacy to that of intramuscular naloxone given at the same dose for reversal of opioid overdose.
There is a significantly increased risk of prescription opioid deaths for those born between 1947 and 1964.
There may be more health benefits at a lower cost with immediate access to opioid agonist treatment for patients with opioid use disorder.
There is a higher risk for opioid-related death in patients taking concomitant prescription opioids and gabapentin.
Medicare Part D formularies increasingly used quantity limits and prior authorization in order to reduce dosing of prescription opioids.
After surgical procedures, the optimal length of opioid prescription lies between the observed median prescription length and the early nadir.
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