Orphenadrine 25mg/Aspirin 385mg/Caffeine 30mg Rx
Generic Name and Formulations:
Orphenadrine citrate 25mg, aspirin 385mg, caffeine 30mg; tabs.
Various generic manufacturers
Indications for Orphenadrine 25mg/Aspirin 385mg/Caffeine 30mg:
Painful musculoskeletal conditions.
1–2 tabs 3–4 times daily.
NSAID allergy. Varicella or influenza in teenagers. Glaucoma. Achalasia. GU or GI obstruction. Myasthenia gravis.
Coronary disease, insufficiency or tachycardia. History of bronchospasm. Peptic ulcer. Coagulation disorders. Monitor blood pressure, BUN, uric acid levels. Pregnancy (Cat.C). Nursing mothers.
Anticholinergic + salicylate.
Increased risk of GI bleed/ulcer with alcohol, aspirin, NSAIDs, corticosteroids, anticoagulants. Potentiates oral hypoglycemics, anticholinergics, protein-bound drugs (eg, warfarin). Antagonizes steroids, barbiturates, phenylbutazone, uricosurics. Tremor and mental confusion with propoxyphene.
Tachycardia, transient dizziness or syncope, GI upset/bleed, anticholinergic effects (eg, dry mouth, blurred vision, increased intraocular pressure, urinary retention), weakness, headache, rash, blood dyscrasias.
Formerly known under the brand names Norgesic (25/385/30); Norgesic Forte (50/770/60).
Neurology Advisor Articles
- Excess Abdominal Obesity Linked to Severe Disability in Multiple Sclerosis
- Change in Dietary Patterns Over 5 Years in Early Multiple Sclerosis
- High-Dose Biotin May Be an Effective Treatment for Progressive MS
- Biobank Data Suggest Vitamin D Reduces Risk for Multiple Sclerosis
- Poor Functional Outcomes Tied to Depressive Symptoms in Multiple Sclerosis
- Managing Status Epilepticus in Palliative Care: Accounting for Patient and Family Experience
- Oxygen Desaturation Index Predicts AFib Risk in Ischemic Stroke
- Opioid Use Down With 'Enhanced Recovery After Surgery' Program
- Popular Heroin Inhalation Method Tied to Leukoencephalopathy
- Erenumab Superior to Placebo for Reducing Migraine Disability, Improving HRQoL