Overview A clear distinction must be established between acute, episodic constipation and chronic constipation. Acute constipation is experienced by nearly every person at some point and can be simply described as self-limited difficult or infrequent defecation. Continue Reading Chronic constipation is difficult defecation experienced for more than 12 weeks, which need not be consecutive, that…
How can I be sure that the patient has Wilson disease? Overview Wilson disease (WD) is an autosomal recessive disorder that results from mutations in the ATP7B gene located on the long arm of chromosome 13. More than 500 mutations have been identified. ATP7B protein is responsible for both hepatic copper incorporation into ceruloplasmin and…
Are You Confident of the Diagnosis? A delusion is a false belief that is not consistent with the cultural standards or educational level of the individual, and that is unshakable in face of all evidence to the contrary. The patients whom we see in dermatology have “systematized” delusions. These, in contrast to “bizarre” delusions, are…
Are You Confident of the Diagnosis? What you should be alert for in the history Trichotillomania (TTM) refers to a condition in which the individual pulls out his or her own hair. This is primarily a psychiatric disorder, and much of the relevant clinical and statistical information is in the psychiatric literature. Because of this,…
The treatment is currently being evaluated in a Phase 2 study (ELEVATE) in patients with major depressive disorder who have had an inadequate response to standard antidepressant therapy.
Migraine and Headache
People with migraines and comorbid mood disorders often need treatments that address both conditions, as well as management of sleep, stress, and lifestyle issues.
Transcranial magnetic stimulation (TMS) uses magnetic fields to stimulate nerve cells in the brain.
Delay or lack of speech, seizures, and walking/balance disorders are some of the symptoms associated with AS.
Mirtazapine is a central alpha-2 antagonist currently FDA-approved for the treatment of major depressive disorder.
Investigators sought to determine the frequency of major depressive disorder in patients in epilepsy clinics.