A study was conducted to determine the effects of switching or augmenting antidepressant therapy in adults with treatment-resistant depression.
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Patients who had treatment-naïve MDD were recruited in the US between 2007 and 2013 for the Predictors of Remission in Depression to Individual and Combined Treatments (PReDICT) study.
Treatment-resistant depression episodes tied to more psychiatric comorbid conditions, health care utilization, self-harm, and all-cause mortality
Investigators looked into which treatment fared better for patients with anxiety disorders: a mindfulness-based stress reduction intervention or escitalopram.
Reduction in caregiver depressive symptoms may have positive impact on child asthma outcomes, partially mediated by child depressive symptom severity
Researchers examined correlations between suicidal ideation and suicide attempt history in patients with treatment-resistant depression following ketamine infusion.
Screening for MDD recommended for teens aged 12 to 18 years; anxiety screening recommended for children aged 8 to 18 years
Looking at stress and university students during the COVID-19 pandemic.
Individuals with severe mental illness or T2DM have increased levels of peripheral immune-inflammatory biomarkers, which may contribute to neurocognitive and social deficits.
To learn more about the impact of depression therapy on anxiety symptoms, researchers conducted a randomized controlled clinical trial with teenagers to compare the results of personalized depression therapy to a program that does not match their risk factors.
Researchers explored the neurobiology related to reward-based reinforcement learning and psychomotor retardation in patients in remission from MDD.
Data for this study were sourced from 4 active treatment arms of 4 randomized, controlled trials conducted by the National Institutes of Health in the United States between 2006 and 2018.
With transgender and gender non-conforming individuals in China subject to minority stress and, as a result a higher risk of adverse mental health issues, researchers aimed to review the findings of the research on transgender and gender non-conforming individuals in that country. By doing so researchers hope to give an outlook to further research that can guide clinical practice and policy.
In a recent survey, more than half the college students with ADHD had at least 1 psychiatric disorder. The recent WHO World Mental Health Survey of college students assessed comorbidities in more than 15,000 college freshmen across 9 countries.
For patients with severe mental illness, a smartphone intervention is highly usable and acceptable and improves outcomes.
Universal school-based MDD screening increases identification of adolescents with MDD symptoms and initiation of treatment.
Researchers compared the effects of 4 contemporary ablative neurosurgical procedures on treatment-resistant psychiatric symptoms.
Use of ketamine and esketamine for their antidepressant effects does not seem to have harmful neurocognitive effects in individuals with treatment-resistant depression.
The outpatient procedure provides noninvasive magnetic stimulation through a cushioned helmet to targeted areas of the brain.
This was a study protocol for a phase II pilot feasibility study that will assess the feasibility of ketamine for depression in patients with advanced life-limiting illnesses.
Ensemble is an AI-powered digital mental health coach app designed to address the symptoms of MDD or GAD.
Patients with depression can live with symptoms for a long period of time before finding an option that works. One possibility for patients who are unable to find relief through pharmacology is transcranial magnetic stimulation. An expert offers his view on this form of treatment.
Major depressive episodes reduce visual contrast suppression among patients with depressive disorders, a study shows.
Psilocybin has been shown to have antidepressant properties. With direct comparisons between psilocybin and established treatments for depression lacking, the study researchers looked at psilocybin and escitalopram.
For patients with MDD, the change in scores for depression at six weeks does not differ significantly with psilocybin or psilocybin plus escitalopram.
Researchers performed a double-blind randomized study to investigate the efficacy of tDCS as an augmentation strategy to sertraline in the treatment of vascular depression.
Most older adults with preexisting MDD showed resilience in the first two months of the COVID-19 pandemic, but they express concerns about the future.
The approval was based on the ASPIRE I and II trials that compared the efficacy and safety of esketamine, an N-methyl-D-aspartate receptor antagonist, to placebo in 449 adults with moderate to severe MDD who had active suicidal ideation and intent.
Depression has been linked to elevated markers of inflammation, and aspirin, a nonsteroid, anti-inflammatory medication, can irreversibly inhibit cyclooxygenase-1 and 2.
Can mere light become a revolutionary new treatment for traumatic brain injury, posttraumatic stress disorder, depression, stroke, Parkinson disease, and Alzheimer disease?
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