Your search for major depressive disorder returned 154 results

Depression has been linked to elevated markers of inflammation, and aspirin, a nonsteroid, anti-inflammatory medication, can irreversibly inhibit cyclooxygenase-1 and 2.

Children who receive a depression diagnosis in their primary school age have a substantially higher risk of a depression relapse during adolescence compared with children who did not receive a depression diagnosis during their primary school age.

Heightened cognitive arousal at bedtime is linked to objective sleep disturbances and indicators of psychological hyperarousal at night and during the day.

Convergent abnormalities were observed in secondary analyses across portions of the amygdala, hippocampus, subgenual cingulate cortex, and putamen.

While the relationship between current mood state and cognitive impairment is unclear, more severe depression has been linked to greater impairment.

While insomnia medication efficacy has been studied in meta-analyses, this efficacy has largely been focused on study endpoints rather than time-course responses.

Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a disorder characterized by marked fatigue, exertion induced malaise, cognitive clouding (or brain fog), impaired academic/work performance, disrupted sleep, and joint/muscle pain.

The researchers concluded that the correlation between interregional cortical thinning during maturation and expression patterns of genes associated with multiple psychiatric disorders suggested a common molecular process.

The FDA has granted Breakthrough Therapy designation to AXS-05 (Axsome Therapeutics) for the treatment of Alzheimer disease agitation.

Investigators posit that wearable devices will help psychiatrists to target mood and cognitive interventions.

Digital CBT involved 6 weekly remote sessions via website or iOS app lasting approximately 20 minutes and comprised sleep restriction, stimulus control, relaxation techniques, cognitive therapy, and sleep hygiene and education.

Children with PANS have cerebral microstructural differences in multiple brain structures, including the deep gray matter structures.

The degree of overlap between MDD and burnout is unclear. However, dysfunctional sleep patterns are known risk factors for both conditions.

Can mere light become a revolutionary new treatment for traumatic brain injury, posttraumatic stress disorder, depression, stroke, Parkinson disease, and Alzheimer disease?

The study compared improvements in frontal lobe dysfunction induced by rTMS and improvement of white matter integrity revealed by diffusion tensor imaging in patients with TRD receiving rTMS treatment.

The FDA has approved Somryst™ (Pear Therapeutics), a prescription digital therapeutic (PDT) intended for the treatment of patients 22 years of age and older with chronic insomnia.

Recent shifts in studies of sex and gender reiterate the critical need to tailor mental health care to each patient and to remain mindful about assumptions regarding sex and gender and their role in a given patient’s specific challenges.

Telmisartan did not affect biomarkers of central nervous system inflammation or injury when used as an adjunct to ART for acute HIV infection.

The influence of gut microbiota extends to the brain via neuroinflammation, resulting in symptoms associated with major depressive disorder.

Depression contributed to elevated ratings in patients with MDD on items related to perceived inability to cope with the negative consequences of disturbed sleep and reported tendency to cancel social plans after poor sleep.

Patients with psychotic depression who experienced an illness relapse while receiving placebo also had a decline in cortical thickness, emphasizing the essential role antipsychotics play in treating disorders where psychosis is present.

Overall, in all patients with MDD, sleep ultradian cycle number was positively associated with REMS percentage, REMS duration, and REMS/NREMS ratio and negatively associated with REM latency.

There is an emerging view that sleep disorders are not merely symptoms of psychiatric conditions; instead there may be a complex, bidirectional relationship between psychiatric and sleep disorders.

Responses to treatment depend on the target chosen, with 5 targets yielding positive outcomes, including the ventral anterior limb of the internal capsule, subthalamic nucleus, nucleus accumbens, ventral capsule/ventral striatum, or inferior thalamic peduncle, all involving fronto-striato-thalamocortical circuits.

The study provides strong evidence for the utility of resting-state fMRI measures in predicting the development of attentional or mood disorders in children.

In boys but not girls, reduced sleep duration at age 8 and 10 years predicted the development of behavioral disorder symptoms 2 years later.

Researchers sought to address the possible link between cognitive or mood symptoms and statins.

Anna S. Urrila, MD and colleagues sought to explore whether sleep symptoms in adolescents with MDD were associated with long-term outcomes.

Common comorbidities in OSA such as cardiovascular disease and metabolic abnormalities, may confer a higher risk for the development of mental and cognitive impairment in patients with OSA compared with the general population.

Various migraine subgroups based on comorbidities can predict the risk for the progression of episodic migraine to chronic migraine.