SSRI use after intracerebral hemorrhage may resolve depression symptoms, but also increases patients’ risk for recurrent stroke.
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Individuals with relapsing-remitting MS who respond suboptimally to DMT may experience improvement with the addition of an SSRI.
In early Parkinson Disease, fatigue, excessive daytime sleepiness, and emotional apathy are predictive of increasing fatigue severity.
Study findings do not support the use of vitamin D3 supplementation to prevent depression in adults.
The use of genetic evaluation for suicidal ideation may represent a future application for precision medicine.
The applications are supported by positive results from a double-masked, 4-week, pivotal phase 2/3 clinical trial that compared the effects of tasimelteon to placebo in 25 patients with SMS.
Children who receive a depression diagnosis in their primary school age have a substantially higher risk of a depression relapse during adolescence compared with children who did not receive a depression diagnosis during their primary school age.
Heightened cognitive arousal at bedtime is linked to objective sleep disturbances and indicators of psychological hyperarousal at night and during the day.
While insomnia medication efficacy has been studied in meta-analyses, this efficacy has largely been focused on study endpoints rather than time-course responses.
Digital CBT involved 6 weekly remote sessions via website or iOS app lasting approximately 20 minutes and comprised sleep restriction, stimulus control, relaxation techniques, cognitive therapy, and sleep hygiene and education.
Children with PANS have cerebral microstructural differences in multiple brain structures, including the deep gray matter structures.
The study compared improvements in frontal lobe dysfunction induced by rTMS and improvement of white matter integrity revealed by diffusion tensor imaging in patients with TRD receiving rTMS treatment.
The FDA has approved Somryst™ (Pear Therapeutics), a prescription digital therapeutic (PDT) intended for the treatment of patients 22 years of age and older with chronic insomnia.
Telmisartan did not affect biomarkers of central nervous system inflammation or injury when used as an adjunct to ART for acute HIV infection.
Various migraine subgroups based on comorbidities can predict the risk for the progression of episodic migraine to chronic migraine.
Among those with acute migraine, intranasal lidocaine has been investigated for efficacy in decreasing initial pain and reducing the need for rescue medication.
Investigators sought to establish the effect of hyperglycemia and metformin use on relevant B-vitamin biomarkers and cognitive outcomes in older adults.
Computerized cognitive training significantly improved global cognitive function in patients with subcortical vascular cognitive impairment.
The results of this review are applicable primarily to persons with focal onset seizures, with 88% of included participants experiencing this type of seizure at baseline.
Investigators assessed demographic and epilepsy-specific factors independently associated with anxiety, including lesions and seizure focus localization.
Investigators aim to facilitate early recognition and consideration for patients with Duchenne muscular dystrophy and internalizing psychiatric symptoms.
A study evaluated the long-term adverse effects of maternal depression on child development.
For adults with bipolar depression, tDCS seems to be safe and effective as an add-on intervention.
Most patients undergoing skull base irradiation for cancer do not have detectable cognitive impairment.
Eli Lilly reports more positive phase 3 data for its acute migraine drug lasmiditan, while yet another brain-training company comes under fire for making baseless claims.
Prescriptions for benzodiazepine lasting 2-3 months or more and marked dose increases should be avoided.
Overall, 26 of the 34 studies suggested a positive relationship between insomnia and depression.
The device is used to condition the patient to reduce or stop their aggressive behavior.
Hippocampal DVR was strongly correlated with the Beck’s Depression Inventory score in patients with MS.
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