Pain Management

Potentially Inappropriate Opioid Prescribing Tied to Overdose

Potentially Inappropriate Opioid Prescribing Tied to Overdose

Potentially inappropriate prescribing (PIP) of opioids is associated with increased risk of all-cause mortality and fatal and nonfatal overdose.

FDA: Opioid Analgesic REMS Expanded to Include Immediate-Release Products

FDA: Opioid Analgesic REMS Expanded to Include Immediate-Release Products

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As part of the REMS program, drug companies with approved opioid analgesics must make training available to prescribers and provide unrestricted grants to accredited continuing education providers for the development of education courses.

Opioids Often Prescribed in the Absence of Pain Diagnosis

Opioids Often Prescribed in the Absence of Pain Diagnosis

Many outpatient opioid prescriptions have no documented medical indication.

Oxycontin's Maker Now Selling Drug to Curb Opioid Addiction

Oxycontin's Maker Now Selling Drug to Curb Opioid Addiction

Purdue Pharma, the maker of Oxycontin who some have blamed for the epidemic of opioid painkiller addictions, has patented a medicine aimed at curbing those disorders.

With New Persistent Opioid Use, Most Early Scripts From Surgeons

With New Persistent Opioid Use, Most Early Scripts From Surgeons

Among surgical patients who develop new persistent opioid use, surgeons provide the majority of opioid prescriptions in the first few months after surgery.

Opioid Maker to Pay for Overdose Antidote Development

Opioid Maker to Pay for Overdose Antidote Development

A $3.4 million grant to help a non-profit company develop a less expensive opioid overdose antidote was announced by Purdue Pharma, which makes the opioid painkiller OxyContin.

FDA Outlines Plan for New Analgesic Guidance to Combat Opioid Crisis

FDA Outlines Plan for New Analgesic Guidance to Combat Opioid Crisis

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The new plan will break out the current guidance into 4 separate guidances.

US Opioid Use Not Declining, Despite Focus on Abuse

US Opioid Use Not Declining, Despite Focus on Abuse

Rates of opioid use in the United States do not appear to be declining.

FDA Warning Letters Target Illegal Online Sales of Opioids

FDA Warning Letters Target Illegal Online Sales of Opioids

Four more online networks that operate 21 websites illegally selling potentially dangerous, unapproved, and misbranded versions of opioid pain medications have been told to immediately stop their sales.

Odds of Death Up With Exposure to Pregabalin, Opioids

Odds of Death Up With Exposure to Pregabalin, Opioids

Concomitant exposure to pregabalin and opioids is associated with increased odds of opioid-related death.

DEA Proposal Will Significantly Cut Opioid Manufacturing in 2019

DEA Proposal Will Significantly Cut Opioid Manufacturing in 2019

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Last year, the DEA proposed a 20% reduction in the manufacturing of controlled substances for 2018 compared to 2017.

Anticonvulsants Seem to Be Ineffective for Low Back Pain

Anticonvulsants Seem to Be Ineffective for Low Back Pain

Anticonvulsant drugs are ineffective for chronic low back pain and can cause harm, despite a recent increase in prescribing.

New Rules May Constrain Docs' Ability to Treat Chronic Pain

New Rules May Constrain Docs' Ability to Treat Chronic Pain

New laws and regulations designed to limit the use of prescription narcotics may further constrain doctors' ability to treat patients.

NIH Initiative Aims to Address Opioid Misuse Over Long Term

NIH Initiative Aims to Address Opioid Misuse Over Long Term

A novel, innovative initiative is being developed to help end addiction over the long term.

Meds for Opioid Use Disorder May Reduce Mortality in OD Survivors

Meds for Opioid Use Disorder May Reduce Mortality in OD Survivors

Use of medications for opioid use disorder is associated with a reduction in all-cause and opioid-related mortality after opioid overdose.

Illicit Opioid Trade Up With Restrictions on Hydrocodone

Illicit Opioid Trade Up With Restrictions on Hydrocodone

The US Drug Enforcement Administration's 2014 ruling to reschedule hydrocodone combination products coincided with an increase in illicit trading of opioids through online illicit markets.

FDA Warns Websites Marketing Unapproved Opioids

FDA Warns Websites Marketing Unapproved Opioids

Nine online networks have been warned that they must stop illegally marketing potentially dangerous, and misbranded versions of opioid medications.

FDA: Opioid Antidote Naloxone Recalled

FDA: Opioid Antidote Naloxone Recalled

A recall of the opioid overdose antidote Naloxone was announced Monday.

NDA for First-of-Its-Kind Opioid Analgesic Submitted to FDA

NDA for First-of-Its-Kind Opioid Analgesic Submitted to FDA

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A NDA has been submitted for NKTR-181, an opioid analgesic molecule designed to provide pain relief with fewer CNS-mediated side effects.

Psychological Therapies May Help Older Adults With Chronic Pain

Psychological Therapies May Help Older Adults With Chronic Pain

For older adults with chronic pain, psychological interventions have small benefits, including reducing pain and catastrophizing beliefs.

Neuroscience Education, Motor Control Training Ease Spinal Pain

Neuroscience Education, Motor Control Training Ease Spinal Pain

For individuals with chronic spinal pain, pain neuroscience education combined with cognition-targeted motor control training seems more effective than PT.

Education, Depression, Pain Associated With Opioid Misuse

Education, Depression, Pain Associated With Opioid Misuse

Higher education, illicit drug use, depression, and pain interference with normal work are significantly associated with opioid misuse.

Marijuana Legalization May Reduce Opioid Use

Marijuana Legalization May Reduce Opioid Use

State implementation of medical marijuana laws is associated with a reduction in the rate of opioid prescribing.

Risk of Altered Mental Status in Gabapentin-Treated Patients Explored

Risk of Altered Mental Status in Gabapentin-Treated Patients Explored

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The study included 110,184 adults (mean age: 76 years) newly started on gabapentin therapy in Ontario, Canada.

Acupuncture for Pain: Pros and Cons

Acupuncture for Pain: Pros and Cons

The reasons for and against recommending acupuncture as pain treatment are discussed.

Factors Associated With Gabapentin Overuse

Factors Associated With Gabapentin Overuse

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The odds of gabapentin overuse are significantly higher in patients who were co-prescribed opioids.

Topical Lidocaine Approved for Postherpetic Neuralgia Pain

Topical Lidocaine Approved for Postherpetic Neuralgia Pain

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The FDA has approved ZTlido to relieve pain associated with postherpetic neuralgia.

Opioid Disposal Improved With Educational Brochure

Opioid Disposal Improved With Educational Brochure

Disposal of unused opioids after surgery is improved with an educational brochure.

Opioid Prescriptions Up With Low Socioeconomic Level

Opioid Prescriptions Up With Low Socioeconomic Level

The authors examined the demographic and geographic variation and the correlation between the local economic environment and measures of individual opioid prescriptions.

Managing Chronic Pain Associated With Traumatic Brain Injury

Managing Chronic Pain Associated With Traumatic Brain Injury

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Chronic pain is common after traumatic brain injury.

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