Pain News Archive
A bipartisan bill meant to combat the United States' opioid abuse epidemic was signed into law October 24 by President Donald Trump.
Dorsal root ganglion neurostimulation therapy may reduce pain and disability in patients with chronic lower extremity and back pain.
The FDA is not bound by the Committee's recommendation but takes it into consideration when making its decision.
Receiving prescriptions from both the US Department of Veterans Affairs and Medicare Part D is associated with increased risk for overlapping of opioid and benzodiazepine prescriptions.
A bipartisan bill to fight the opioid addiction crisis in the United States has been passed by Congress.
An "enhanced recovery after surgery" program is associated with a significant reduction in opioid consumption after gynecologic surgery with no increase in pain scores.
In a rare bipartisan move, both the House and Senate have reached a compromise on legislation to address the opioid epidemic.
Potentially inappropriate prescribing (PIP) of opioids is associated with increased risk of all-cause mortality and fatal and nonfatal overdose.
As part of the REMS program, drug companies with approved opioid analgesics must make training available to prescribers and provide unrestricted grants to accredited continuing education providers for the development of education courses.
About 20.4% of US adults have chronic pain and 8.0% have high-impact chronic pain.
Many outpatient opioid prescriptions have no documented medical indication.
Chronic pain may be an important contributor to suicide, with 8.8 percent of suicide decedents having evidence of chronic pain.
Purdue Pharma, the maker of Oxycontin who some have blamed for the epidemic of opioid painkiller addictions, has patented a medicine aimed at curbing those disorders.
Among surgical patients who develop new persistent opioid use, surgeons provide the majority of opioid prescriptions in the first few months after surgery.
A $3.4 million grant to help a non-profit company develop a less expensive opioid overdose antidote was announced by Purdue Pharma, which makes the opioid painkiller OxyContin.
The new plan will break out the current guidance into 4 separate guidances.
Rates of opioid use in the United States do not appear to be declining.
Four more online networks that operate 21 websites illegally selling potentially dangerous, unapproved, and misbranded versions of opioid pain medications have been told to immediately stop their sales.
Concomitant exposure to pregabalin and opioids is associated with increased odds of opioid-related death.
New laws and regulations designed to limit the use of prescription narcotics may further constrain doctors' ability to treat patients.
In back-related leg pain and sciatica patients, belief in a long recovery and the number of other symptoms attributed to the pain are independently negatively associated with improvement.
A novel, innovative initiative is being developed to help end addiction over the long term.
Use of medications for opioid use disorder is associated with a reduction in all-cause and opioid-related mortality after opioid overdose.
The US Drug Enforcement Administration's 2014 ruling to reschedule hydrocodone combination products coincided with an increase in illicit trading of opioids through online illicit markets.
Nine online networks have been warned that they must stop illegally marketing potentially dangerous, and misbranded versions of opioid medications.
A recall of the opioid overdose antidote Naloxone was announced Monday.
A NDA has been submitted for NKTR-181, an opioid analgesic molecule designed to provide pain relief with fewer CNS-mediated side effects.
For older adults with chronic pain, psychological interventions have small benefits, including reducing pain and catastrophizing beliefs.
For individuals with chronic spinal pain, pain neuroscience education combined with cognition-targeted motor control training seems more effective than PT.
Higher education, illicit drug use, depression, and pain interference with normal work are significantly associated with opioid misuse.
State implementation of medical marijuana laws is associated with a reduction in the rate of opioid prescribing.
The study included 110,184 adults (mean age: 76 years) newly started on gabapentin therapy in Ontario, Canada.
The reasons for and against recommending acupuncture as pain treatment are discussed.
Disposal of unused opioids after surgery is improved with an educational brochure.
The authors examined the demographic and geographic variation and the correlation between the local economic environment and measures of individual opioid prescriptions.
There is a significantly increased risk of prescription opioid deaths for those born between 1947 and 1964.
There may be more health benefits at a lower cost with immediate access to opioid agonist treatment for patients with opioid use disorder.
Significant structural and functional brain changes in movement and pain regions are demonstrated by patients with CRPS.
For adolescents with chronic pain, a combination of different therapies such as CBT and breathing exercises may be beneficial.
A probable diagnosis of fibromyalgia can be indicated with 2 simple tests in chronic pain patients.
There is a higher risk for opioid-related death in patients taking concomitant prescription opioids and gabapentin.
After surgical procedures, the optimal length of opioid prescription lies between the observed median prescription length and the early nadir.
The CDC is is launching a campaign to help fight the opioid crisis.
It is recommended that physicians educate their patients/their patients' family members regarding the steps to take in case of a potential overdose.
The most opioid use occurs in the top 10% of privately insured adults without cancer who are using opioids.
The Intellis platform has been announced as a way to manage certain types of chronic pain.
As a response to the opioid epidemic, clinicians may be overprescribing gabapentinoids.
Even though there are concerns about opioid addiction and misuse, there are still more than 1/3 of Americans using them.
Ketamine was found to alleviate a number of pain-related conditions, and a number of clinical trials investigating its efficacy are ongoing.
Quality of life and improved pain and function may be achieved by reducing opioid doses.
Hospitalists must use opioids judiciously, including adhering to specific dose limits and setting expectations for pain control, medication stop dates, and refills.
Patients with chronic pain may have a lower risk of becoming addicted to opioids if they are taught coping skills.
PNS can be beneficial for chronic intractable pain secondary to postherpetic neuralgia.
The NASEM report, which was commissioned by the FDA, gives an update on current research in the pain field.
Older adults with chronic pain have been found to have poorer memory and executive function than their younger counterparts.
An FDA panel previously voted that the drug's benefits no longer outweigh its risks.
Reports of pain may indicate a preclinical course of amyotrophic lateral sclerosis.
The VA and DoD issue a clinical practice guideline regarding opioid therapy for chronic pain in veterans.
Clinically and statistically significant reductions in peripheral neuropathy were seen following neurofeedback.
Spinal cord stimulation using precision approach via 3D neural targeting shows superior efficacy in treating chronic axial low back pain compared with a trial-and-error method to achieve desired paresthesia.
The recommendations promote the use of hot compresses and physical therapy as first-line treatment of low back pain.
New research suggests that opioid addiction may be linked to a genetic variant, and more personalized treatment may help those with the change.
Interventions with clinical massage or guided imagery may help ease pain and anxiety in patients in a progressive care unit.
The abuse of opioids or other substances may cause short-term amnesia.
Patients with successful spinal cord stimulation implants had significantly reduced opioid use 1 year post-implant.
Effectively treating pain may help improve cognitive and functional outcomes in patients with depression.
The FDA instituted widespread updates to product labeling for opioid medications in December, 2016.
Rates of severe pain were significantly higher in veterans with back and jaw pain, severe headaches or migraine, and neck pain.
The US FDA is requiring that label changes be made to reflect the risks involved with extended exposure to anesthetics and sedatives in children and pregnant women.
After treatment, there were marked decreases in visual analog scale (VAS)-pain, VAS-asthenia, severity of waking unrefreshed, tender point count, and Beck Depression Inventory.
The researchers observed a 47.5% increase in the percentage of participants who had a final pain score of 4 or less out of 10.
Even after loss of exclusivity, pregabalin has lower health care costs than gabapentin.
Kratom may be used to develop nonaddictive alternatives to opioids.
Alternative treatments include endomorphins, spinal cord stimulation, and psychotherapy.
Novice prescribers cited insufficient access to substance abuse counseling for patients, as well as insufficient access to more experienced prescribers, as reasons for not treating more patients.
Pain treatments often target either the brain or body, but data show that treatments often benefit both.
A patient with a baseline pain score of 60 on a scale of 0 to 100 would be expected to have a pain score of 45 after a non-acupuncture intervention; 35 after a sham acupuncture intervention; and 30 after true acupuncture.
Approaches such as acupuncture, massage, and tai chi may ease discomfort.
Opioid usage may exacerbate the problem.
Patients who underwent thoracic surgery were at the greatest risk of long-term opioid use.
A surprising number of patients already prescribed opioids were found to be abusing gabapentin.
The 6-month implant is more expensive than the pills, costing about $4,900 -- or more than $800 a month.
A restricted number of surgical procedures are not associated with increased incidence of chronic opioid use.
American medical school students spend much less time learning about pain than their international peers.
Much of the risk is related to cardiovascular complications, not overdoses.
This new form of treatment is designed to last 6 months.
There has been a 12 to 18% drop in opioid prescriptions since 2012.
Sleep disruption alters positive affective pain modulation.
An FDA committee will meet this week to review the risk-management plans.
The effects of the opioid-relapse prevention treatment waned after treatment discontinuation.
Twenty-five percent of doctors write month-long opioid prescriptions.
The new guideline is the latest in an overhaul designed to curb opioid abuse.
Revised labeling will occur across all types of opioids.
Some concerns include a lack of evidence underlying recommendations.
While mindfulness meditation has previously been associated with pain relief, the mechanistic action behind this has been unclear.
The new guidelines come in the wake of an opioid overdose epidemic in the U.S.
Targeted physicians prescribed 400% more controlled substances than their peers.
The FDA has accepted an NDA for Arymo ER (morphine sulfate; Egalet) extended-release tablets.
Those who presented with serious infections were more likely to currently be using opioids.
Functional MRI with central sensitization was found beneficial for selecting analgesics.
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