Pain News Archive

Bill to Fight US Opioid Crisis Signed Into Law

Bill to Fight US Opioid Crisis Signed Into Law

A bipartisan bill meant to combat the United States' opioid abuse epidemic was signed into law October 24 by President Donald Trump.

ASA: Dorsal Root Ganglion Stimulation Disrupts Back Pain

ASA: Dorsal Root Ganglion Stimulation Disrupts Back Pain

Dorsal root ganglion neurostimulation therapy may reduce pain and disability in patients with chronic lower extremity and back pain.

FDA Panel Votes on Drug/Device Combo to Treat Pain in Medically Supervised Setting

FDA Panel Votes on Drug/Device Combo to Treat Pain in Medically Supervised Setting

The FDA is not bound by the Committee's recommendation but takes it into consideration when making its decision.

Risk of Opioid-Benzodiazepine Overlap Up for Dual Prescribing

Risk of Opioid-Benzodiazepine Overlap Up for Dual Prescribing

Receiving prescriptions from both the US Department of Veterans Affairs and Medicare Part D is associated with increased risk for overlapping of opioid and benzodiazepine prescriptions.

Congress Passes Bill to Fight Opioid Crisis

Congress Passes Bill to Fight Opioid Crisis

A bipartisan bill to fight the opioid addiction crisis in the United States has been passed by Congress.

Opioid Use Down With 'Enhanced Recovery After Surgery' Program

Opioid Use Down With 'Enhanced Recovery After Surgery' Program

An "enhanced recovery after surgery" program is associated with a significant reduction in opioid consumption after gynecologic surgery with no increase in pain scores.

Opioid Bill Gets Bipartisan Support

Opioid Bill Gets Bipartisan Support

In a rare bipartisan move, both the House and Senate have reached a compromise on legislation to address the opioid epidemic.

Potentially Inappropriate Opioid Prescribing Tied to Overdose

Potentially Inappropriate Opioid Prescribing Tied to Overdose

Potentially inappropriate prescribing (PIP) of opioids is associated with increased risk of all-cause mortality and fatal and nonfatal overdose.

FDA: Opioid Analgesic REMS Expanded to Include Immediate-Release Products

FDA: Opioid Analgesic REMS Expanded to Include Immediate-Release Products

As part of the REMS program, drug companies with approved opioid analgesics must make training available to prescribers and provide unrestricted grants to accredited continuing education providers for the development of education courses.

CDC: About One in Five U.S. Adults Have Chronic Pain

CDC: About One in Five U.S. Adults Have Chronic Pain

About 20.4% of US adults have chronic pain and 8.0% have high-impact chronic pain.

Opioids Often Prescribed in the Absence of Pain Diagnosis

Opioids Often Prescribed in the Absence of Pain Diagnosis

Many outpatient opioid prescriptions have no documented medical indication.

Chronic Pain May Be Contributor to Suicide

Chronic Pain May Be Contributor to Suicide

Chronic pain may be an important contributor to suicide, with 8.8 percent of suicide decedents having evidence of chronic pain.

Oxycontin's Maker Now Selling Drug to Curb Opioid Addiction

Oxycontin's Maker Now Selling Drug to Curb Opioid Addiction

Purdue Pharma, the maker of Oxycontin who some have blamed for the epidemic of opioid painkiller addictions, has patented a medicine aimed at curbing those disorders.

With New Persistent Opioid Use, Most Early Scripts From Surgeons

With New Persistent Opioid Use, Most Early Scripts From Surgeons

Among surgical patients who develop new persistent opioid use, surgeons provide the majority of opioid prescriptions in the first few months after surgery.

Opioid Maker to Pay for Overdose Antidote Development

Opioid Maker to Pay for Overdose Antidote Development

A $3.4 million grant to help a non-profit company develop a less expensive opioid overdose antidote was announced by Purdue Pharma, which makes the opioid painkiller OxyContin.

FDA Outlines Plan for New Analgesic Guidance to Combat Opioid Crisis

FDA Outlines Plan for New Analgesic Guidance to Combat Opioid Crisis

The new plan will break out the current guidance into 4 separate guidances.

US Opioid Use Not Declining, Despite Focus on Abuse

US Opioid Use Not Declining, Despite Focus on Abuse

Rates of opioid use in the United States do not appear to be declining.

FDA Warning Letters Target Illegal Online Sales of Opioids

FDA Warning Letters Target Illegal Online Sales of Opioids

Four more online networks that operate 21 websites illegally selling potentially dangerous, unapproved, and misbranded versions of opioid pain medications have been told to immediately stop their sales.

Odds of Death Up With Exposure to Pregabalin, Opioids

Odds of Death Up With Exposure to Pregabalin, Opioids

Concomitant exposure to pregabalin and opioids is associated with increased odds of opioid-related death.

New Rules May Constrain Docs' Ability to Treat Chronic Pain

New Rules May Constrain Docs' Ability to Treat Chronic Pain

New laws and regulations designed to limit the use of prescription narcotics may further constrain doctors' ability to treat patients.

Various Factors Affect Progress in Back-Related Leg Pain, Sciatica

Various Factors Affect Progress in Back-Related Leg Pain, Sciatica

In back-related leg pain and sciatica patients, belief in a long recovery and the number of other symptoms attributed to the pain are independently negatively associated with improvement.

NIH Initiative Aims to Address Opioid Misuse Over Long Term

NIH Initiative Aims to Address Opioid Misuse Over Long Term

A novel, innovative initiative is being developed to help end addiction over the long term.

Meds for Opioid Use Disorder May Reduce Mortality in OD Survivors

Meds for Opioid Use Disorder May Reduce Mortality in OD Survivors

Use of medications for opioid use disorder is associated with a reduction in all-cause and opioid-related mortality after opioid overdose.

Illicit Opioid Trade Up With Restrictions on Hydrocodone

Illicit Opioid Trade Up With Restrictions on Hydrocodone

The US Drug Enforcement Administration's 2014 ruling to reschedule hydrocodone combination products coincided with an increase in illicit trading of opioids through online illicit markets.

FDA Warns Websites Marketing Unapproved Opioids

FDA Warns Websites Marketing Unapproved Opioids

Nine online networks have been warned that they must stop illegally marketing potentially dangerous, and misbranded versions of opioid medications.

FDA: Opioid Antidote Naloxone Recalled

FDA: Opioid Antidote Naloxone Recalled

A recall of the opioid overdose antidote Naloxone was announced Monday.

NDA for First-of-Its-Kind Opioid Analgesic Submitted to FDA

NDA for First-of-Its-Kind Opioid Analgesic Submitted to FDA

A NDA has been submitted for NKTR-181, an opioid analgesic molecule designed to provide pain relief with fewer CNS-mediated side effects.

Psychological Therapies May Help Older Adults With Chronic Pain

Psychological Therapies May Help Older Adults With Chronic Pain

For older adults with chronic pain, psychological interventions have small benefits, including reducing pain and catastrophizing beliefs.

Neuroscience Education, Motor Control Training Ease Spinal Pain

Neuroscience Education, Motor Control Training Ease Spinal Pain

For individuals with chronic spinal pain, pain neuroscience education combined with cognition-targeted motor control training seems more effective than PT.

Education, Depression, Pain Associated With Opioid Misuse

Education, Depression, Pain Associated With Opioid Misuse

Higher education, illicit drug use, depression, and pain interference with normal work are significantly associated with opioid misuse.

Marijuana Legalization May Reduce Opioid Use

Marijuana Legalization May Reduce Opioid Use

State implementation of medical marijuana laws is associated with a reduction in the rate of opioid prescribing.

Risk of Altered Mental Status in Gabapentin-Treated Patients Explored

Risk of Altered Mental Status in Gabapentin-Treated Patients Explored

The study included 110,184 adults (mean age: 76 years) newly started on gabapentin therapy in Ontario, Canada.

Acupuncture for Pain: Pros and Cons

Acupuncture for Pain: Pros and Cons

The reasons for and against recommending acupuncture as pain treatment are discussed.

Opioid Disposal Improved With Educational Brochure

Opioid Disposal Improved With Educational Brochure

Disposal of unused opioids after surgery is improved with an educational brochure.

Opioid Prescriptions Up With Low Socioeconomic Level

Opioid Prescriptions Up With Low Socioeconomic Level

The authors examined the demographic and geographic variation and the correlation between the local economic environment and measures of individual opioid prescriptions.

Baby Boomers at High Risk for Death From Prescription Opioid Overdose

Baby Boomers at High Risk for Death From Prescription Opioid Overdose

There is a significantly increased risk of prescription opioid deaths for those born between 1947 and 1964.

Immediate Access to Opioid Agonists Reduces Associated Health Care Costs

Immediate Access to Opioid Agonists Reduces Associated Health Care Costs

There may be more health benefits at a lower cost with immediate access to opioid agonist treatment for patients with opioid use disorder.

Structural, Functional Brain Changes Seen in Complex Regional Pain Syndrome

Structural, Functional Brain Changes Seen in Complex Regional Pain Syndrome

Significant structural and functional brain changes in movement and pain regions are demonstrated by patients with CRPS.

Brief Group-Based Cognitive Intervention Effective for Adolescent Chronic Pain

Brief Group-Based Cognitive Intervention Effective for Adolescent Chronic Pain

For adolescents with chronic pain, a combination of different therapies such as CBT and breathing exercises may be beneficial.

Diagnosing Fibromyalgia in Chronic Pain Patients With Simple Exams

Diagnosing Fibromyalgia in Chronic Pain Patients With Simple Exams

A probable diagnosis of fibromyalgia can be indicated with 2 simple tests in chronic pain patients.

Gabapentin, Opioid Combo May Increase Risk of Opioid-Related Death

Gabapentin, Opioid Combo May Increase Risk of Opioid-Related Death

There is a higher risk for opioid-related death in patients taking concomitant prescription opioids and gabapentin.

What's the Optimal Length of Post-Op Opioid Tx?

What's the Optimal Length of Post-Op Opioid Tx?

After surgical procedures, the optimal length of opioid prescription lies between the observed median prescription length and the early nadir.

Campaign Launched by CDC to Fight Opioid Crisis

Campaign Launched by CDC to Fight Opioid Crisis

The CDC is is launching a campaign to help fight the opioid crisis.

AMA Recommendation on Naloxone Co-Prescribing

AMA Recommendation on Naloxone Co-Prescribing

It is recommended that physicians educate their patients/their patients' family members regarding the steps to take in case of a potential overdose.

Top 10% of Opioid Users Account for Most Drug Use

Top 10% of Opioid Users Account for Most Drug Use

The most opioid use occurs in the top 10% of privately insured adults without cancer who are using opioids.

FDA Approves Device for Tx of Chronic Pain

FDA Approves Device for Tx of Chronic Pain

The Intellis platform has been announced as a way to manage certain types of chronic pain.

Gabapentinoid Prescribing Trends: Are We Using Too Much?

Gabapentinoid Prescribing Trends: Are We Using Too Much?

As a response to the opioid epidemic, clinicians may be overprescribing gabapentinoids.

Excessive Opioid Prescribing Still Rampant in US

Excessive Opioid Prescribing Still Rampant in US

Even though there are concerns about opioid addiction and misuse, there are still more than 1/3 of Americans using them.

Ketamine Update: Usage, Benefits, and Current Research

Ketamine Update: Usage, Benefits, and Current Research

Ketamine was found to alleviate a number of pain-related conditions, and a number of clinical trials investigating its efficacy are ongoing.

Opioid Dose Reduction May Improve Quality of Life in Chronic Pain

Opioid Dose Reduction May Improve Quality of Life in Chronic Pain

Quality of life and improved pain and function may be achieved by reducing opioid doses.

The Role of Hospitalists in Addressing the Opioid Crisis

The Role of Hospitalists in Addressing the Opioid Crisis

Hospitalists must use opioids judiciously, including adhering to specific dose limits and setting expectations for pain control, medication stop dates, and refills.

Acceptance Therapy May Reduce Opioid Dependence in Patients

Acceptance Therapy May Reduce Opioid Dependence in Patients

Patients with chronic pain may have a lower risk of becoming addicted to opioids if they are taught coping skills.

Peripheral Nerve Stimulation Effective for Postherpetic Neuralgia

Peripheral Nerve Stimulation Effective for Postherpetic Neuralgia

PNS can be beneficial for chronic intractable pain secondary to postherpetic neuralgia.

Curbing the Opioid Epidemic: A National Academies of Science Report

Curbing the Opioid Epidemic: A National Academies of Science Report

The NASEM report, which was commissioned by the FDA, gives an update on current research in the pain field.

Pain Linked to Memory Decline, Dementia Risk

Pain Linked to Memory Decline, Dementia Risk

Older adults with chronic pain have been found to have poorer memory and executive function than their younger counterparts.

FDA Moves to Remove Opioid From the Market

FDA Moves to Remove Opioid From the Market

An FDA panel previously voted that the drug's benefits no longer outweigh its risks.

Preclinical Pain in Amyotrophic Lateral Sclerosis May Be a Marker for Diagnosis, Treatment

Preclinical Pain in Amyotrophic Lateral Sclerosis May Be a Marker for Diagnosis, Treatment

Reports of pain may indicate a preclinical course of amyotrophic lateral sclerosis.

New Guidelines: Opioids for Chronic Pain in the VA Health System

New Guidelines: Opioids for Chronic Pain in the VA Health System

The VA and DoD issue a clinical practice guideline regarding opioid therapy for chronic pain in veterans.

Neurofeedback Aids in Reducing Nerve Damage from Chemo

Neurofeedback Aids in Reducing Nerve Damage from Chemo

Clinically and statistically significant reductions in peripheral neuropathy were seen following neurofeedback.

Neural Targeting Spinal Cord Stimulation Superior for Axial Low Back Pain

Neural Targeting Spinal Cord Stimulation Superior for Axial Low Back Pain

Spinal cord stimulation using precision approach via 3D neural targeting shows superior efficacy in treating chronic axial low back pain compared with a trial-and-error method to achieve desired paresthesia.

Updated Guidelines for Treatment of Low Back Pain

Updated Guidelines for Treatment of Low Back Pain

The recommendations promote the use of hot compresses and physical therapy as first-line treatment of low back pain.

VIDEO: Opioid Addiction May Be Linked to Genetic Variant

New research suggests that opioid addiction may be linked to a genetic variant, and more personalized treatment may help those with the change.

Clinical Massage, Guided Imagery May Improve Insomnia, Pain

Clinical Massage, Guided Imagery May Improve Insomnia, Pain

Interventions with clinical massage or guided imagery may help ease pain and anxiety in patients in a progressive care unit.

Opioid Abuse May Be Linked to Sudden-Onset Amnesia

Opioid Abuse May Be Linked to Sudden-Onset Amnesia

The abuse of opioids or other substances may cause short-term amnesia.

Spinal Cord Stimulation May Reduce Opioid Use in Chronic Pain

Spinal Cord Stimulation May Reduce Opioid Use in Chronic Pain

Patients with successful spinal cord stimulation implants had significantly reduced opioid use 1 year post-implant.

Treating Pain in Depression May Help Improve Cognition

Treating Pain in Depression May Help Improve Cognition

Effectively treating pain may help improve cognitive and functional outcomes in patients with depression.

FDA Updates Opioid Drug Label Information

FDA Updates Opioid Drug Label Information

The FDA instituted widespread updates to product labeling for opioid medications in December, 2016.

Veterans Experience More Pain Than General Population

Veterans Experience More Pain Than General Population

Rates of severe pain were significantly higher in veterans with back and jaw pain, severe headaches or migraine, and neck pain.

FDA Issues Warning for Children, Pregnant Women With Extended Exposure to Anesthetics

FDA Issues Warning for Children, Pregnant Women With Extended Exposure to Anesthetics

The US FDA is requiring that label changes be made to reflect the risks involved with extended exposure to anesthetics and sedatives in children and pregnant women.

Is Vitamin D the Answer in Chronic Widespread Pain?

Is Vitamin D the Answer in Chronic Widespread Pain?

After treatment, there were marked decreases in visual analog scale (VAS)-pain, VAS-asthenia, severity of waking unrefreshed, tender point count, and Beck Depression Inventory.

Quality Improvements for Pain Management in the ER

Quality Improvements for Pain Management in the ER

The researchers observed a 47.5% increase in the percentage of participants who had a final pain score of 4 or less out of 10.

Pregabalin vs Gabapentin for Neuropathic Pain: Which Costs Less?

Pregabalin vs Gabapentin for Neuropathic Pain: Which Costs Less?

Even after loss of exclusivity, pregabalin has lower health care costs than gabapentin.

DEA Delays Decision to Ban Kratom

DEA Delays Decision to Ban Kratom

Kratom may be used to develop nonaddictive alternatives to opioids.

Alternative Treatments for the Management of Chronic Pain

Alternative Treatments for the Management of Chronic Pain

Alternative treatments include endomorphins, spinal cord stimulation, and psychotherapy.

Consequences of Limiting Physicians' Prescribing of Buprenorphine

Consequences of Limiting Physicians' Prescribing of Buprenorphine

Novice prescribers cited insufficient access to substance abuse counseling for patients, as well as insufficient access to more experienced prescribers, as reasons for not treating more patients.

Should Pain Treatments Target the Brain or Body?

Should Pain Treatments Target the Brain or Body?

Pain treatments often target either the brain or body, but data show that treatments often benefit both.

Acupuncture for Treatment of Chronic Pain Conditions

Acupuncture for Treatment of Chronic Pain Conditions

A patient with a baseline pain score of 60 on a scale of 0 to 100 would be expected to have a pain score of 45 after a non-acupuncture intervention; 35 after a sham acupuncture intervention; and 30 after true acupuncture.

Alternative Pain Management Therapies Effective

Alternative Pain Management Therapies Effective

Approaches such as acupuncture, massage, and tai chi may ease discomfort.

Sleep Disturbance Common in Chronic Pain

Sleep Disturbance Common in Chronic Pain

Opioid usage may exacerbate the problem.

Elderly May Be at Lower Risk of Opioid Abuse

Elderly May Be at Lower Risk of Opioid Abuse

Patients who underwent thoracic surgery were at the greatest risk of long-term opioid use.

Illicit Use of Gabapentin on the Rise

Illicit Use of Gabapentin on the Rise

A surprising number of patients already prescribed opioids were found to be abusing gabapentin.

Buprenorphine Implant Effective for Reducing Opioid Dependence

Buprenorphine Implant Effective for Reducing Opioid Dependence

The 6-month implant is more expensive than the pills, costing about $4,900 -- or more than $800 a month.

Risk of Chronic Opioid Use After Common Surgeries

Risk of Chronic Opioid Use After Common Surgeries

A restricted number of surgical procedures are not associated with increased incidence of chronic opioid use.

Medical Schools Stepping Up Opioid Abuse Training

Medical Schools Stepping Up Opioid Abuse Training

American medical school students spend much less time learning about pain than their international peers.

Opioid Use Mortality Linked to Cardiovascular Complications

Opioid Use Mortality Linked to Cardiovascular Complications

Much of the risk is related to cardiovascular complications, not overdoses.

FDA Approval: First Probuphine Implant for Opioid Dependence

FDA Approval: First Probuphine Implant for Opioid Dependence

This new form of treatment is designed to last 6 months.

Opioid Prescriptions Drop, but Overdose Deaths Still Rising

Opioid Prescriptions Drop, but Overdose Deaths Still Rising

There has been a 12 to 18% drop in opioid prescriptions since 2012.

Sleep Disruption Alters Pain Sensitivity

Sleep Disruption Alters Pain Sensitivity

Sleep disruption alters positive affective pain modulation.

FDA Considers Mandatory Opioid Prescribing Training

FDA Considers Mandatory Opioid Prescribing Training

An FDA committee will meet this week to review the risk-management plans.

Naltrexone Injection Reduces Opioid Relapse Risk

Naltrexone Injection Reduces Opioid Relapse Risk

The effects of the opioid-relapse prevention treatment waned after treatment discontinuation.

Opioids Being Prescribed for Longer Than Recommended

Opioids Being Prescribed for Longer Than Recommended

Twenty-five percent of doctors write month-long opioid prescriptions.

FDA Issues Guidance on Generic Abuse-Deterrent Opioids

FDA Issues Guidance on Generic Abuse-Deterrent Opioids

The new guideline is the latest in an overhaul designed to curb opioid abuse.

Opioid Medications to Get New Boxed Warnings

Opioid Medications to Get New Boxed Warnings

Revised labeling will occur across all types of opioids.

Physicians Sound Off On New CDC Opioid Guidelines

Physicians Sound Off On New CDC Opioid Guidelines

Some concerns include a lack of evidence underlying recommendations.

Non-Opioid Pathway Could Alter the Way We Treat Chronic Pain

Non-Opioid Pathway Could Alter the Way We Treat Chronic Pain

While mindfulness meditation has previously been associated with pain relief, the mechanistic action behind this has been unclear.

CDC Issues Guideline for Prescribing Opioids for Chronic Pain

CDC Issues Guideline for Prescribing Opioids for Chronic Pain

The new guidelines come in the wake of an opioid overdose epidemic in the U.S.

Informative Letters Fail to Stop Physicians From Overprescribing

Informative Letters Fail to Stop Physicians From Overprescribing

Targeted physicians prescribed 400% more controlled substances than their peers.

FDA Accepts NDA for Controlled Opioid Agonist

FDA Accepts NDA for Controlled Opioid Agonist

The FDA has accepted an NDA for Arymo ER (morphine sulfate; Egalet) extended-release tablets.

Opioids Associated With Infection Risk in Rheumatoid Arthritis

Opioids Associated With Infection Risk in Rheumatoid Arthritis

Those who presented with serious infections were more likely to currently be using opioids.

Functional MRI May Help In Pain Medicine Development

Functional MRI May Help In Pain Medicine Development

Functional MRI with central sensitization was found beneficial for selecting analgesics.

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