Pain

White Matter Hyperintensities Demonstrate Specific Spatiotemporal Evolution in Reversible Cerebral Vasoconstriction Syndrome

White Matter Hyperintensities Demonstrate Specific Spatiotemporal Evolution in Reversible Cerebral Vasoconstriction Syndrome

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The characteristics of white matter hyperintensities were assessed to provide information on the underlying mechanisms of these lesions in individuals with reversible cerebral vasoconstriction syndrome.

Co-Prescription of Opioids and Antidepressants Prevalent in Migraine

Co-Prescription of Opioids and Antidepressants Prevalent in Migraine

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Researchers sought to assess the prevalence of concomitant prescribing of opioid analgesics with a triptan or a serotogeneric antidepressant in individuals with migraine.

Anticonvulsants Seem to Be Ineffective for Low Back Pain

Anticonvulsants Seem to Be Ineffective for Low Back Pain

Anticonvulsant drugs are ineffective for chronic low back pain and can cause harm, despite a recent increase in prescribing.

New Rules May Constrain Docs' Ability to Treat Chronic Pain

New Rules May Constrain Docs' Ability to Treat Chronic Pain

New laws and regulations designed to limit the use of prescription narcotics may further constrain doctors' ability to treat patients.

Various Factors Affect Progress in Back-Related Leg Pain, Sciatica

Various Factors Affect Progress in Back-Related Leg Pain, Sciatica

In back-related leg pain and sciatica patients, belief in a long recovery and the number of other symptoms attributed to the pain are independently negatively associated with improvement.

NIH Initiative Aims to Address Opioid Misuse Over Long Term

NIH Initiative Aims to Address Opioid Misuse Over Long Term

A novel, innovative initiative is being developed to help end addiction over the long term.

Meds for Opioid Use Disorder May Reduce Mortality in OD Survivors

Meds for Opioid Use Disorder May Reduce Mortality in OD Survivors

Use of medications for opioid use disorder is associated with a reduction in all-cause and opioid-related mortality after opioid overdose.

Illicit Opioid Trade Up With Restrictions on Hydrocodone

Illicit Opioid Trade Up With Restrictions on Hydrocodone

The US Drug Enforcement Administration's 2014 ruling to reschedule hydrocodone combination products coincided with an increase in illicit trading of opioids through online illicit markets.

FDA Warns Websites Marketing Unapproved Opioids

FDA Warns Websites Marketing Unapproved Opioids

Nine online networks have been warned that they must stop illegally marketing potentially dangerous, and misbranded versions of opioid medications.

FDA: Opioid Antidote Naloxone Recalled

FDA: Opioid Antidote Naloxone Recalled

A recall of the opioid overdose antidote Naloxone was announced Monday.

NDA for First-of-Its-Kind Opioid Analgesic Submitted to FDA

NDA for First-of-Its-Kind Opioid Analgesic Submitted to FDA

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A NDA has been submitted for NKTR-181, an opioid analgesic molecule designed to provide pain relief with fewer CNS-mediated side effects.

Psychological Therapies May Help Older Adults With Chronic Pain

Psychological Therapies May Help Older Adults With Chronic Pain

For older adults with chronic pain, psychological interventions have small benefits, including reducing pain and catastrophizing beliefs.

Neuroscience Education, Motor Control Training Ease Spinal Pain

Neuroscience Education, Motor Control Training Ease Spinal Pain

For individuals with chronic spinal pain, pain neuroscience education combined with cognition-targeted motor control training seems more effective than PT.

Pain, Psychiatric Comorbidities More Common in Chronic vs Episodic Migraine

Pain, Psychiatric Comorbidities More Common in Chronic vs Episodic Migraine

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Individuals with chronic vs episodic migraine may be more likely to experience chronic back pain, chronic pain, neck pain, anxiety, and depression.

Education, Depression, Pain Associated With Opioid Misuse

Education, Depression, Pain Associated With Opioid Misuse

Higher education, illicit drug use, depression, and pain interference with normal work are significantly associated with opioid misuse.

Marijuana Legalization May Reduce Opioid Use

Marijuana Legalization May Reduce Opioid Use

State implementation of medical marijuana laws is associated with a reduction in the rate of opioid prescribing.

Risk of Altered Mental Status in Gabapentin-Treated Patients Explored

Risk of Altered Mental Status in Gabapentin-Treated Patients Explored

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The study included 110,184 adults (mean age: 76 years) newly started on gabapentin therapy in Ontario, Canada.

Acupuncture for Pain: Pros and Cons

Acupuncture for Pain: Pros and Cons

The reasons for and against recommending acupuncture as pain treatment are discussed.

Factors Associated With Gabapentin Overuse

Factors Associated With Gabapentin Overuse

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The odds of gabapentin overuse are significantly higher in patients who were co-prescribed opioids.

Poor Sleep Associated With Worse PTSD, Chronic Pain in Youth

Poor Sleep Associated With Worse PTSD, Chronic Pain in Youth

For youth, poor sleep worsens the associations between PTSD symptoms and chronic pain.

Fentanyl Use Associated With Amnesia: Case Report

Fentanyl Use Associated With Amnesia: Case Report

Another case of unusual amnestic syndrome that includes bilateral hippocampal lesions on MRI has been described.

Opioid Disposal Improved With Educational Brochure

Opioid Disposal Improved With Educational Brochure

Disposal of unused opioids after surgery is improved with an educational brochure.

Opioid Prescriptions Up With Low Socioeconomic Level

Opioid Prescriptions Up With Low Socioeconomic Level

The authors examined the demographic and geographic variation and the correlation between the local economic environment and measures of individual opioid prescriptions.

Common Causes of Chronic Pain Management Malpractice Claims

Common Causes of Chronic Pain Management Malpractice Claims

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There is a growing emphasis on provider responsibility with the increasing focus of the overprescribing of opioids.

Intranasal, Intramuscular Naloxone Equally As Effective for Opioid Overdose

Intranasal, Intramuscular Naloxone Equally As Effective for Opioid Overdose

Higher-concentration intranasal naloxone has similar efficacy to that of intramuscular naloxone given at the same dose for reversal of opioid overdose.

Managing Chronic Pain Associated With Traumatic Brain Injury

Managing Chronic Pain Associated With Traumatic Brain Injury

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Chronic pain is common after traumatic brain injury.

Baby Boomers at High Risk for Death From Prescription Opioid Overdose

Baby Boomers at High Risk for Death From Prescription Opioid Overdose

There is a significantly increased risk of prescription opioid deaths for those born between 1947 and 1964.

Immediate Access to Opioid Agonists Reduces Associated Health Care Costs

Immediate Access to Opioid Agonists Reduces Associated Health Care Costs

There may be more health benefits at a lower cost with immediate access to opioid agonist treatment for patients with opioid use disorder.

Spinal Cord Stimulation Reduces Pain Associated With Diabetic Polyneuropathy

Spinal Cord Stimulation Reduces Pain Associated With Diabetic Polyneuropathy

Chronic pain symptoms in patients with PDPN are effectively reduced with spinal cord stimulation.

Structural, Functional Brain Changes Seen in Complex Regional Pain Syndrome

Structural, Functional Brain Changes Seen in Complex Regional Pain Syndrome

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Significant structural and functional brain changes in movement and pain regions are demonstrated by patients with CRPS.

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