Partial Onset Seizures
Potiga tablets have been discontinued due to the limited use of the medicine.
Sunovion has filed a supplemental NDA with the FDA to expand the indication for Aptiom to pediatric patients with partial onset seizures.
The drug is the first and only IV formulation of the antiepileptic carbamazepine.
Results from a 2-year extension study confirm the safety and efficacy of lacosamid monotherapy.
Similar plasma concentration, adverse events observed compared to oral administration.
Surgery had a significant impact on mortality even if seizures were not completely eliminated.
The drug targets the synaptic vesicle protein 2A, which may contribute to the anticonvulsive effect.
Dr Mary Zupanc of CHOC Children's recounts a challenging case of refractory seizures in a child with a history of arteriovenous malformation and intracranial hemorrhage.
Both the 100 and 200 mg/d dose were found to be safe and effective in POS patients 16 years and older.
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