Pediatric Neurology

Age, Sex Affect Extended Post-Concussion Symptoms in Children

Age, Sex Affect Extended Post-Concussion Symptoms in Children

Age, sex, and family factors play a role in the persistence of post-concussion symptoms one year after injury.

Fingolimod shows superior efficacy to interferon beta-1a in pediatric multiple sclerosis: the PARADIGMS trial

Among pediatric patients with relapsing multiple sclerosis, fingolimod was associated with a lower annualized rate of relapse and lower incidence of new lesions identified on T2-weighted magnetic resonance imaging (MRI) compared to interferon beta-1a.

Global Cognition Up for Youth Meeting Movement Guidelines

Global Cognition Up for Youth Meeting Movement Guidelines

Meeting recommendations on adequate sleep time and physical activity and limiting recreational screen time are associated with superior global cognition among children.

Insufficient Sleep Tied to Unsafe Behaviors in High School Students

Insufficient Sleep Tied to Unsafe Behaviors in High School Students

For high school students, sleeping less than eight hours on an average school night is associated with increased odds of selected unsafe behaviors.

Prevalence of TBI 2.5% Among  US Children

Prevalence of TBI 2.5% Among US Children

The prevalence of traumatic brain injury is 2.5% among US children, and TBI is associated with several health conditions.

Percentile-Based Systolic Blood Pressure Targets Better Identify Hypotension in Severe Pediatric TBI

Percentile-Based Systolic Blood Pressure Targets Better Identify Hypotension in Severe Pediatric TBI

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The investigators observed an increased risk for in-hospital mortality among patients with systolic blood pressure in the <75th percentile across all ages.

Head CT Decision Aid Ups Parent Knowledge in Child Head Trauma

Head CT Decision Aid Ups Parent Knowledge in Child Head Trauma

Use of a decision aid can improve parent knowledge for children with minor head injury at intermediate risk of clinically important traumatic brain injury.

Cannabinoid Trials Needed for Peds Neurologic Disorders

Cannabinoid Trials Needed for Peds Neurologic Disorders

There is an urgent need for clinical trials to investigate the use of cannabinoids in pediatric patients with neurological disorders.

Repeat CT Common in Peds Traumatic Epidural Hematoma

Repeat CT Common in Peds Traumatic Epidural Hematoma

For children with traumatic epidural hematomas (EDHs), repeated computed tomography imaging is common, but rarely impacts management.

Educational Disabilities More Likely With Neonatal Abstinence

Educational Disabilities More Likely With Neonatal Abstinence

Children with a history of neonatal abstinence syndrome are more likely to be referred for a disability evaluation and meet criteria for a disability.

Fingolimod Cuts Multiple Sclerosis Relapses in Pediatric Patients

Fingolimod Cuts Multiple Sclerosis Relapses in Pediatric Patients

Among pediatric patients with relapsing multiple sclerosis, fingolimod is associated with a lower rate of relapse but a higher rate of serious adverse events.

Despite guidelines, use of CT for head trauma in children remains unchanged

The Pediatric Emergency Care Applied Research Network published clinical prediction rules in 2009 to identify children with head trauma for whom computed tomography neuroimaging can be avoided.

Parents' Technology Use Can Negatively Impact Children

Parents' Technology Use Can Negatively Impact Children

Parents' use of digital devices may exacerbate their child's poor behavior.

Early Talk, Interaction Predicts School-Age Language Outcomes

Early Talk, Interaction Predicts School-Age Language Outcomes

Talk and interaction during early childhood, especially during 18 to 24 months, is associated with language and cognitive outcomes.

X-Rays, Blood Tests Not Advised for Children's Concussions

X-Rays, Blood Tests Not Advised for Children's Concussions

Routine X-rays and blood tests should not be used to diagnose children's concussions, new US government guidelines say.

Last 20 Years Saw Increase in Prevalence of ADHD in Children

Last 20 Years Saw Increase in Prevalence of ADHD in Children

From 1997-1998 to 2015-2016, there was an increase in the prevalence of ADHD among children,

New Guideline for Pediatric Mild Traumatic Brain Injury Diagnosis, Management

New Guideline for Pediatric Mild Traumatic Brain Injury Diagnosis, Management

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Gradually increasing academic pursuits requires careful planning among the medical, school, and family units to enable prompt return and avoidance of prolonging school absence.

Everolimus, Sirolimus Generally Safe for Epilepsy in Tuberous Sclerosis Complex

Everolimus, Sirolimus Generally Safe for Epilepsy in Tuberous Sclerosis Complex

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Approximately 78% of treated patients experienced at least 1 treatment-related adverse event.

Ethical Challenges of Nusinersen: Considerations When Counseling on Treatment

Ethical Challenges of Nusinersen: Considerations When Counseling on Treatment

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Although regarded as a miracle drug to some, nusinersen comes with some troublesome strings attached.

Lower Socioeconomic Status Linked to Worse Outcomes in Pediatric Arterial Ischemic Stroke

Lower Socioeconomic Status Linked to Worse Outcomes in Pediatric Arterial Ischemic Stroke

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The root causes of the disparity reported among families of different income levels are unclear and deserve additional investigation.

Cerebral Blood Flow Changes in Pediatric Patients With CKD

Cerebral Blood Flow Changes in Pediatric Patients With CKD

Pediatric patients with chronic kidney disease have higher global cerebral blood flow and regional differences in CBF.

Therapeutic Plasma Exchange Effectively Improves Ambulation in Pediatric Transverse Myelitis

Therapeutic Plasma Exchange Effectively Improves Ambulation in Pediatric Transverse Myelitis

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Treatment with TPE was well tolerated in 108 of 114 treatments.

Neurodevelopmental Anomalies, Birth Defects Linked to Zika ID'd

Neurodevelopmental Anomalies, Birth Defects Linked to Zika ID'd

Many children of mothers with evidence of confirmed or possible Zika virus infection during pregnancy do not undergo all recommended evaluations.

Alcohol Exposure Via Breastmilk May Affect Infant Development

Alcohol Exposure Via Breastmilk May Affect Infant Development

Exposing infants to alcohol through breastfeeding may reduce their cognitive ability at age 6 to 7 years.

Vagus Nerve Stimulation in Pediatric Epilepsy: Weighing the Risks and Benefits

Vagus Nerve Stimulation in Pediatric Epilepsy: Weighing the Risks and Benefits

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Studies that have evaluated the use of VNS in children, including those as young as 6 months old, and have generally concluded that it is well tolerated and improves quality of life.

Medical Cannabis Promising for Dystonia Improvement in Pediatric Motor Disorders

Medical Cannabis Promising for Dystonia Improvement in Pediatric Motor Disorders

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Children with a complex motor disorder, characterized by a combination of movement and posture abnormalities (eg, spasticity and dystonia), were enrolled.

Worse Outcomes With Dyskinesia Than With Spasticity in Cerebral Palsy

Worse Outcomes With Dyskinesia Than With Spasticity in Cerebral Palsy

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Across the entire cohort, the predominant motor types featured were 70% spastic, 22% dyskinetic (21% dystonic and 1% choreoathetotic), 6% hypotonic, and 2% ataxic.

Outpatient Opioid Prescriptions for Children Often Filled

Outpatient Opioid Prescriptions for Children Often Filled

Children often fill outpatient opioid prescriptions, with the most common indication for dental procedures.

Specific Neuroimaging Findings May Predict School-Age Cognitive Disability in Preterm Infants

Specific Neuroimaging Findings May Predict School-Age Cognitive Disability in Preterm Infants

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Severe and adverse late findings on neonatal cranial ultrasound and MRI in preterm infants, including cerebellar lesions and white matter abnormalities, may predict cognitive impairment and disability at 6 to 7 years of age.

Link Between Lower Cognitive Ability in Young Adults and Risk for Dementia

Link Between Lower Cognitive Ability in Young Adults and Risk for Dementia

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Lower cognitive ability total and verbal ability scores were predictive of greater risk for early-onset dementia.

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