A study evaluated the long-term adverse effects of maternal depression on child development.
The Agency has received reports of serious neural tube birth defects involving the brain, spine, and spinal cord in babies born to women who received dolutegravir for HIV treatment.
Congenital Heart Disease, Hispanic Ethnicity Associated With Increased Mortality in Pediatric Arterial Ischemic StrokeMay 21, 2018
The investigators were unable to determine which type of congenital heart disease or which type of ventricular assist device, if used, played a role in mortality outcomes.
Children hospitalized for traumatic brain injury tend to have unmet needs for educational and rehabilitation services approximately 2 years after a traumatic brain injury event.
Childhood cancer survivors frequently have clinical abnormalities attributable to peripheral neuropathy.
Children with prenatal exposure to serotonin reuptake inhibitors have better executive function at age 12 years.
The FDA's decision was based on data from the Phase 3 PARADIGMS study (N=215) which evaluated the safety and efficacy of oral fingolimod vs interferon beta-1a injection in pediatric patients aged 10 to <18 years with relapsing MS.
Greater sugar consumption during pregnancy and early childhood may adversely impact child cognition.
Previous studies have shown that delayed-release DMF is safe and effective in treating RRMS in adult patients. The goal of this study was to extend these analyses to evaluate DMF in pediatric patients with RRMS.
Ventriculomegaly, Polymicrogyria Predict Epilepsy Risk Among Pediatric Patients With Cytomegalovirus InfectionsMay 04, 2018
Investigators retrospectively reviewed the patients' medical records and MRI images and assessed the associations between the MRI findings and neurologic outcomes, specifically neurodevelopmental achievement, epilepsy, and sensorineural hearing loss.
A team of investigators assessed the effect of intravenous administration of methylprednisolone on duration of episodes in adolescent and young adult patients with Kleine-Levin syndrome.
Researchers conducted post-hoc analysis of data derived from 2 randomized, placebo-controlled trials to determine the safety and tolerability of eslicarbazepine in pediatric patients with partial-onset seizures not responsive to treatment with ≤2 antiepileptic drugs.
Neonatal caffeine therapy for apnea of prematurity has no detrimental long-term effects and even improves some neurologic measures.
This prospective cohort study showed that children born extremely premature or at an extremely low birth weight were more likely to develop cerebral palsy or non-CP motor impairment at 8 years' corrected age when compared to matched controls born at term.
Isolated vomiting was not associated with clinically important TBI or evidence of TBI on computed tomography scans among pediatric patients with head injury.
Iatrogenic steroid-induced psychosis is a rare side effect of glucocorticoid therapy which is mostly seen in adults, although it has been reported in children and adolescents.
Prenatal exposure to a selective serotonin reuptake inhibitor is associated with fetal brain development.
There are significant differences in the development of 12 fiber tracts between infants with fragile X syndrome and controls.
Best diagnostics and evidence-based treatments should be used from the start of the disease.
Among pregnant women with Zika virus infection, birth defects were reported more often in fetuses and infants whose mothers had been infected with the virus early in their pregnancies.
Children presenting with head injury with isolated vomiting rarely have clinically important TBI.
By inhibiting the activation of myostatin, SRK-015 may promote a clinically meaningful increase in muscle mass and strength.
Preventive strategies for reducing the high incidence of bronchopulmonary dysplasia may be key to the improvement of long-term outcomes in EP/VP children.
Improved motor function was observed among more participants in the nusinersen group compared with those in the control group.
Rooming-in with the mother or family members may help reduce pharmacotherapy and increase breastfeeding in newborns with NAS.
Children with chronic kidney disease may have deficits in global and domain-specific cognition.
A multi-site, cross-sectional study found a large mismatch between previously diagnosed fetal alcohol spectrum disorders and the actual prevalence of cases identified.
Fetal alcohol syndrome prevalence ranges from 1.1% to 5.0% among first graders in 4 US communities.
Less than 10% of boys and girls aged 3-17 have ever had a significant head injury in 2016.
For children undergoing MRI with deep sedation, a shorter recovery time is associated with use of ketamine at induction followed by propofol infusion.
Neurology Advisor Articles
- FDA Approves Aimovig for Migraine Prevention
- Prediction Algorithm Stratifies ICH Patients at Risk for Hematoma Expansion
- Sports-Related Concussion Outcomes Predicted With Serum Neurofilament Light
- FDA: Lamotrigine Linked to Potentially Life-Threatening Adverse Reaction
- Psychological Therapies May Help Older Adults With Chronic Pain
- Amyloid Positivity Increases Risk for Cognitive Impairment in Dementia-Free Patients
- Valproic Acid-Related Adverse Fetal Outcomes May Be Linked to Placental Effects
- Risk of Dementia Up for Older Adults With Lowest Wealth
- Language Used in Medical Record Can Affect Patient Care
- Mortality in Alzheimer Disease Not Strongly Associated With Antipsychotics