Progressive Multifocal Leukoencephalopathy (PML)

Plasma Exchange Should Be Used With Caution in Progressive Multifocal Leukoencephalopathy

Plasma Exchange Should Be Used With Caution in Progressive Multifocal Leukoencephalopathy

Plasma exchange and steroids should be used with caution in patients with PML.

Risk for PML in Multiple Sclerosis Predicted With Anti-JCV Antibody Index

Risk for PML in Multiple Sclerosis Predicted With Anti-JCV Antibody Index

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Improving PML risk estimates is an important component of treatment with natalizumab for multiple sclerosis.

Ocrelizumab Approved for Progressive, Relapsing Multiple Sclerosis

Ocrelizumab Approved for Progressive, Relapsing Multiple Sclerosis

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The biannual infusion is approved for the treatment of adults with relapsing and progressive forms of multiple sclerosis.

Dimethyl-Fumarate May Maintain NEDA After Natalizumab Discontinuation

Dimethyl-Fumarate May Maintain NEDA After Natalizumab Discontinuation

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Over 90% of participants achieved NEDA-3 after being transitioned to dimethyl-fumarate from natalizumab.

Imaging Biomarker Diagnoses PML in Patients Taking Natalizumab for MS

Imaging Biomarker Diagnoses PML in Patients Taking Natalizumab for MS

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The clarity of "punctate patterns" on MRI increased with disease severity, with nonenhancing lesions more evident in earlier stages of progressive multifocal leukoencephalopathy.

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