The findings are limited to the 50 most-prescribed non-epilepsy drugs assessed in this Medicare population and may not generalize to non-Medicare beneficiaries who receive other non-epilepsy drugs.
Cannabinoids are effective as an adjunctive treatment for reducing seizure frequency in pediatric-onset treatment-resistant epilepsy.
Investigators sought to validate a tool to identify post-stroke seizure risk.
Participants in the progressive muscle relaxation group reported greater reductions in stress vs those randomized to the focused-attention activity.
Five studies demonstrated a significant improvement in serum 25-hydroxyvitamin D from baseline to post-treatment vitamin D supplementation in patients with epilepsy.
The study findings are particularly relevant given the current mismatch between clinical practice and regulatory approval of levetiracetam in infantile seizures.
The investigators hope that the consensus statement helps resolve several clinical questions in cases of pediatric new onset status epilepticus syndromes.
School performance is lower in children with prenatal exposure to valproate.
No increased risk of incident epilepsy was seen among children who received influenza vaccination during the 2009-2010 influenza season in Norway.
While epilepsy-related head trauma was common, 9 of 10 patients displayed no evidence of CTE.
The FDA has cleared the Embrace smart watch for managing epilepsy.
Add-on cannabidiol is associated with reduced monthy drop seizure frequency in patients with Lennox-Gastaut sydrome associated drop seizures.
Women receiving topiramate for epilepsy were exposed to high cumulative doses, increasing the risk for oral clefts in offspring.
Patients with tough-to-treat seizures may require nonpharmacologic treatment such as resective surgery.
Over one-third of patients with newly diagnosed epilepsy do not respond to antiepileptic drug treatment.
Vitamin B6 was found to effectively treat the behavioral adverse effects seen with levetiracetam.
Research has found that gabapentin and pregabalin induced myoclonus is often seen but is rarely documented.
Lamotrigine and levetiracetam are just as effective as other AEDs, and are better tolerated as well.
The FDA has accepted for filing with Priority Review the NDA for cannabidiol as seizure treatment.
In patients with severe refractory focal epilepsy, add-on treatment with perampanel may be beneficial.
The findings further the utility of cerebral oximetry as a neurological assessment tool.
ZX008 has received Orphan Drug designation and Fast Track designation by the FDA for the treatment of Dravet syndrome.
Researchers from the University of Colorado reported on whether or not maternal antibiotic use during labor increased the risk of seizure for the neonate.
Treatment with enzalutamide for metastatic castration-resistant prostate cancer patients is not linked with increased seizure incidence.
Vigabatrin may be an effective option for patients with seizures due to tuberous sclerosis who do not respond to other anti-seizure treatments.
A study assessed longitudinal behavior in pediatric patients with childhood absence epilepsy and made recommendations regarding initial preferred monotherapy.
Clobazam is currently FDA-approved for the treatment of seizures associated with Lennox-Gastaut syndrome in children 2 years and older.
The diagnostic tool may be especially useful in cases of nonlesional mesial temporal lobe epilepsy.
Patients with refractory epilepsy who fail to benefit from 2 or more AEDs should be referred to alternative therapies.
Patients who died from suspected SUDEP had extensive damage to areas of the mid-brain and brainstem that control autonomic function.
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