Seizures

First Generic Version of Sabril Tablets Gets FDA Approval

First Generic Version of Sabril Tablets Gets FDA Approval

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As treatment with vigabatrin may be associated with permanent vision loss, the generic tablets are also part of a single shared-system Risk Evaluation and Mitigation Strategy (REMS) program to ensure the product is used safely.

Psychotherapy May Reduce Frequency of Nonepileptic Seizures

Psychotherapy May Reduce Frequency of Nonepileptic Seizures

Adherence to psychotherapy is associated with improved outcomes in individuals with psychogenic nonepileptic seizures.

Seizure Monitoring Smartwatch Cleared for Use in Children

Seizure Monitoring Smartwatch Cleared for Use in Children

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The Food and Drug Administration has granted 501(k) clearance to the Embrace watch for use in epilepsy patients aged ≥6 years. The smartwatch identifies generalized tonic-clonic seizures and alerts caregivers.

Researchers ID Factors Predictive of Naming Decline After Epilepsy Surgery

Researchers ID Factors Predictive of Naming Decline After Epilepsy Surgery

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The use of externally validated nomograms in 2 easy-to-use formats can help physicians assess the probability of naming decline in patients considering epilepsy surgery for treatment of pharmacoresistant temporal lobe epilepsy.

CBD Superior to Placebo, Similar to AEDs for Managing Epilepsy Syndromes

CBD Superior to Placebo, Similar to AEDs for Managing Epilepsy Syndromes

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Cannabinoids appeared more effective than placebo and similarly efficacious as other antiepileptic drugs for managing pediatric patients with Dravet syndrome and Lennox-Gastaut syndrome as well as adults with epilepsy.

Postresection Monitoring May Provide Further Insights on Epileptogenic Zone Following Multistage Epilepsy Surgery

Postresection Monitoring May Provide Further Insights on Epileptogenic Zone Following Multistage Epilepsy Surgery

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Investigators found that it may be prudent to continue postoperative invasive monitoring in children who have had surgical resection of epileptic lesions.

Aggressive, Prolonged Treatment for Refractory Status Epilepticus May Be Justified With Good Neurologic Prognosis

Aggressive, Prolonged Treatment for Refractory Status Epilepticus May Be Justified With Good Neurologic Prognosis

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Aggressive and prolonged treatment of refractory status epilepticus may be justified in patients with cardiac arrest with favorable multimodal prognostic indicators.

Multivariable Clinical Trait Model Predicts Childhood Epilepsy Risk

Multivariable Clinical Trait Model Predicts Childhood Epilepsy Risk

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Researchers sought to develop a prediction model that determines the risk for childhood epilepsy and included clinical characteristic variables such as sex, medical history, age of first seizure, and event description, along with electroencephalogram readings.

Heart Rate, Movement Detect Nocturnal Seizures in Epilepsy

Heart Rate, Movement Detect Nocturnal Seizures in Epilepsy

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Investigators examined whether a bracelet capable of measuring heart rate and movement would be beneficial for detecting nocturnal seizures in patients with epilepsy.

Nocturnal Seizures With Convulsions Linked to SUDEP

Nocturnal Seizures With Convulsions Linked to SUDEP

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Investigators sought to predict the incidence of SUDEP in people with intellectual disabilities in residential care settings and to determine its relationship with nocturnal seizures and nocturnal supervision.

Strategies for Reducing Cognitive Deficits in Pediatric Epilepsy

Strategies for Reducing Cognitive Deficits in Pediatric Epilepsy

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In the past, many epilepsy providers have focused solely on seizure control as a way to improve developmental outcomes and HRQOL; however, we now know that the most effective treatment for pediatric epilepsy is comprehensive.

Oxtellar XR Gains Monotherapy Indication for Partial-Onset Seizures

Oxtellar XR Gains Monotherapy Indication for Partial-Onset Seizures

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The FDA has approved the supplemental New Drug Application for Oxtellar XR to include monotherapy use for the treatment of partial-onset seizures patients aged ≥6 years.

Volume Perfusion CT Helps Differentiate Ictal Stroke Mimics, but Not Postictal, From Acute Ischemic Stroke

Volume Perfusion CT Helps Differentiate Ictal Stroke Mimics, but Not Postictal, From Acute Ischemic Stroke

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Patients were initially misjudged to have presented with an acute stroke instead of an epileptic seizure.

Epilepsy, Sleep Apnea, and SUDEP: A Closer Look

Epilepsy, Sleep Apnea, and SUDEP: A Closer Look

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The comorbid presence of central apnea has been identified by multiple researchers as predictive of SUDEP.

Unplanned Pregnancy in Women With Epilepsy Increases Risk for Spontaneous Fetal Loss

Unplanned Pregnancy in Women With Epilepsy Increases Risk for Spontaneous Fetal Loss

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Investigators assessed the effect of unplanned vs planned pregnancies in this patient population on the risk for SFL.

Study Identifies Early-Onset Motor Behaviors in DES-Triggered Seizures

Study Identifies Early-Onset Motor Behaviors in DES-Triggered Seizures

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Investigators evaluated seizure stimulation parameters, electroclinical data, semiology, and anatomical localization in spontaneous and stimulated seizures.

<i>NBEA</i> Gene Associated With Neurodevelopmental Delay, Childhood Epilepsy

NBEA Gene Associated With Neurodevelopmental Delay, Childhood Epilepsy

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Investigators analyzed the NBEA gene to determine whether or not it could be a biomarker for early childhood epilepsy.

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