As treatment with vigabatrin may be associated with permanent vision loss, the generic tablets are also part of a single shared-system Risk Evaluation and Mitigation Strategy (REMS) program to ensure the product is used safely.
Adherence to psychotherapy is associated with improved outcomes in individuals with psychogenic nonepileptic seizures.
The Food and Drug Administration has granted 501(k) clearance to the Embrace watch for use in epilepsy patients aged ≥6 years. The smartwatch identifies generalized tonic-clonic seizures and alerts caregivers.
The use of externally validated nomograms in 2 easy-to-use formats can help physicians assess the probability of naming decline in patients considering epilepsy surgery for treatment of pharmacoresistant temporal lobe epilepsy.
Cannabinoids appeared more effective than placebo and similarly efficacious as other antiepileptic drugs for managing pediatric patients with Dravet syndrome and Lennox-Gastaut syndrome as well as adults with epilepsy.
Postresection Monitoring May Provide Further Insights on Epileptogenic Zone Following Multistage Epilepsy SurgeryJanuary 09, 2019
Investigators found that it may be prudent to continue postoperative invasive monitoring in children who have had surgical resection of epileptic lesions.
Aggressive, Prolonged Treatment for Refractory Status Epilepticus May Be Justified With Good Neurologic PrognosisJanuary 08, 2019
Aggressive and prolonged treatment of refractory status epilepticus may be justified in patients with cardiac arrest with favorable multimodal prognostic indicators.
Researchers sought to develop a prediction model that determines the risk for childhood epilepsy and included clinical characteristic variables such as sex, medical history, age of first seizure, and event description, along with electroencephalogram readings.
Investigators examined whether a bracelet capable of measuring heart rate and movement would be beneficial for detecting nocturnal seizures in patients with epilepsy.
Investigators sought to predict the incidence of SUDEP in people with intellectual disabilities in residential care settings and to determine its relationship with nocturnal seizures and nocturnal supervision.
In the past, many epilepsy providers have focused solely on seizure control as a way to improve developmental outcomes and HRQOL; however, we now know that the most effective treatment for pediatric epilepsy is comprehensive.
The FDA has approved the supplemental New Drug Application for Oxtellar XR to include monotherapy use for the treatment of partial-onset seizures patients aged ≥6 years.
Volume Perfusion CT Helps Differentiate Ictal Stroke Mimics, but Not Postictal, From Acute Ischemic StrokeDecember 18, 2018
Patients were initially misjudged to have presented with an acute stroke instead of an epileptic seizure.
The comorbid presence of central apnea has been identified by multiple researchers as predictive of SUDEP.
Investigators assessed the effect of unplanned vs planned pregnancies in this patient population on the risk for SFL.
Investigators evaluated seizure stimulation parameters, electroclinical data, semiology, and anatomical localization in spontaneous and stimulated seizures.
Investigators analyzed the NBEA gene to determine whether or not it could be a biomarker for early childhood epilepsy.
Neurology Advisor Articles
- Case Study Report: Herbal Supplement Kratom Associated With Neonatal Abstinence Syndrome
- Seizure Monitoring Smartwatch Cleared for Use in Children
- Steps to Facilitate Rapid Reperfusion to Improve Poststroke Outcomes
- Ocrelizumab Reduces Upper Extremity Disability Progression Risk in PPMS
- Cerebellar Stimulation May Help Improve Gait and Balance Recovery in Stroke
- Very Early Mobilization After Stroke Does Not Improve Survival Over Usual Care
- Alemtuzumab Linked to Clinical and MRI Disease Remission in Multiple Sclerosis
- Cognitive Decline Worsens With Memantine, ChEIs in Patients With Alzheimer's
- Cervical Dysfunction Needs Clarification to Identify Link With Headache
- Levodopa Inhalation Powder Approved for Parkinson Disease
- Risk for Conversion of MS Varies With Different Therapies
- Breakdown of Blood-Brain Barrier May Drive Dementia
- FDA: Food Inspections to Resume Despite Ongoing Funding Lapse
- First Generic Version of Sabril Tablets Gets FDA Approval
- Supine Positioning After Greater Occipital Nerve Block May Improve Outcomes