Sleep Disorders

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Xyrem Approved for Use in Pediatric Patients With Narcolepsy

Xyrem Approved for Use in Pediatric Patients With Narcolepsy

Efficacy in the pediatric population with narcolepsy was demonstrated in the Phase 2/3 EXPRESS study (N=106) which included patients aged 7 to 17 years with narcolepsy with cataplexy.

Novel Narcolepsy Treatment Gets Orphan Drug Designation

Novel Narcolepsy Treatment Gets Orphan Drug Designation

The Company stated that they plan to begin a Phase 2 trial of AXS-12 before the end of 2018, with results anticipated for the first half of 2019.

Short Respiratory Event Duration Ups Mortality Risk in OSA

Short Respiratory Event Duration Ups Mortality Risk in OSA

For individuals with obstructive sleep apnea, those with short respiratory event duration have an increased risk for mortality.

Hypoglossal Nerve Stimulation Improves Objective Alertness, Sleep in Obstructive Sleep Apnea

Hypoglossal Nerve Stimulation Improves Objective Alertness, Sleep in Obstructive Sleep Apnea

The investigators found a significant reduction in the mean preimplantation apnea-hypopnea index at 6 months after hypoglossal nerve stimulation.

Positive Results for Lemborexant in Insomnia Disorder Study

Positive Results for Lemborexant in Insomnia Disorder Study

SUNRISE 2 is an ongoing long-term efficacy and safety study (N=900) of adults (aged 18 to 88 years) with insomnia disorder who have difficulty falling and/or staying asleep.

Digital Cognitive Therapy Eases Daytime Effects of Insomnia

Digital Cognitive Therapy Eases Daytime Effects of Insomnia

Digital CBT is effective in improving functional health, psychological well-being, and sleep-related quality of life in people reporting insomnia.

Insufficient Sleep Tied to Unsafe Behaviors in High School Students

Insufficient Sleep Tied to Unsafe Behaviors in High School Students

For high school students, sleeping less than eight hours on an average school night is associated with increased odds of selected unsafe behaviors.

Many Older Adults Transition to Long-Term Benzodiazepine Use

Many Older Adults Transition to Long-Term Benzodiazepine Use

More than one-quarter of older adults newly prescribed benzodiazepine by an non-psychiatric clinician transition to long-term use.

Sleep Apnea Linked to Changes in the Brain in Older Adults

Sleep Apnea Linked to Changes in the Brain in Older Adults

Obstructive sleep apnea is associated with changes to the structure of the brain that are seen in the early stages of dementia.

Acute Insomnia Found to Be Common Among Good Sleepers

Acute Insomnia Found to Be Common Among Good Sleepers

Acute insomnia is common among good sleepers, and about three-quarters of those with AI recover good sleep.

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