Stroke News Archive

MRI Markers Associated With Increased Risk for Stroke, Dementia, Death in Older Adults

MRI Markers Associated With Increased Risk for Stroke, Dementia, Death in Older Adults

Systematic review and meta-analysis provides evidence that white matter hyperintensities, brain infarcts, and cerebral microbleeds indicate a significant increased risk for stroke, dementia, and death in community-dwelling older adults.

Differentiating Intracranial Atherosclerosis vs Dissection: Potential Role of High-Resolution MRI

Differentiating Intracranial Atherosclerosis vs Dissection: Potential Role of High-Resolution MRI

Results indicate that recurrent vascular event rate and changes in vascular status were different between patients with intracranial arterial dissection and those with intracranial atherosclerotic stenosis.

Deep Learning Algorithms Identify CT Scan Abnormalities in Head Trauma, Stroke

Deep Learning Algorithms Identify CT Scan Abnormalities in Head Trauma, Stroke

Researchers developed deep learning algorithms to individually detect up to 9 critical findings on head CT scans.

Quick Take:Effect of Cerebellar Stimulation on Gait and Balance Recovery in Patients With Hemiparetic Stroke: A Randomized Clinical Trial

Impairments in gait and balance are not uncommon after stroke, and are associated with poorer functional recovery.

Quick Take: Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial

The selective serotonin reuptake inhibitor fluoxetine is commonly used in treating depression and emotional lability after stroke.

Volume Perfusion CT Helps Differentiate Ictal Stroke Mimics, but Not Postictal, From Acute Ischemic Stroke

Volume Perfusion CT Helps Differentiate Ictal Stroke Mimics, but Not Postictal, From Acute Ischemic Stroke

Patients were initially misjudged to have presented with an acute stroke instead of an epileptic seizure.

NIHSS May Misjudge Infratentorial Lesions in Thrombolysis-Eligible Stroke

NIHSS May Misjudge Infratentorial Lesions in Thrombolysis-Eligible Stroke

Researchers predict that an NIHSS score ≥6 for an infratentorial stroke may require more aggressive treatment than just thrombolysis alone.

Does a Culturally Tailored Intervention Reduce Long-Term Vascular Risk in Minorities?

Does a Culturally Tailored Intervention Reduce Long-Term Vascular Risk in Minorities?

Culturally tailored, skills-based strategies may be an important alternative to knowledge-focused approaches in achieving sustained vascular risk reduction and addressing racial/ethnic stroke disparities.

Pharyngeal Electrical Stimulation Improves Readiness for Decannulation in Post-Stroke Dysphagia

Pharyngeal Electrical Stimulation Improves Readiness for Decannulation in Post-Stroke Dysphagia

A significantly higher percentage of patients in the pharyngeal electrical stimulation group of the PHAST-TRAC trial were ready for decannulation after 3 days of treatment vs the sham control group.

Neurofilament Light: Biomarker of Neuroaxonal Injury After Ischemic Stroke

Neurofilament Light: Biomarker of Neuroaxonal Injury After Ischemic Stroke

Investigators explored the use of serum neurofilament light chain as a biomarker for primary and secondary neuroaxonal injury after ischemic stroke.

Left Atrial Enlargement Linked to Vascular Brain Injury

Left Atrial Enlargement Linked to Vascular Brain Injury

Investigators examine the association between LAD and vascular brain injury on brain MRI.

Dextroamphetamine Plus Physical Therapy Nonsuperior to Placebo for Improving Post-Stroke Motor Recovery

Dextroamphetamine Plus Physical Therapy Nonsuperior to Placebo for Improving Post-Stroke Motor Recovery

No significant difference was observed between the treatment and placebo arms in change in the Fugl-Meyer motor scores from baseline to 3-month follow-up.

Cannabidiol Gets Orphan Drug Status for Preventing Ischemia-Reperfusion Injury

Cannabidiol Gets Orphan Drug Status for Preventing Ischemia-Reperfusion Injury

The designation was granted to Revive Therapeutics, a company that specializes in cannabis-based pharmaceuticals.

In-Hospital Infection May Up Readmission After Stroke

In-Hospital Infection May Up Readmission After Stroke

For patients with ischemic stroke, infection during stroke hospitalization is associated with increased odds of 30-day readmission.

ACA Implementation Decreased Rates of Therapy Nonadherence in Stroke Survivors

ACA Implementation Decreased Rates of Therapy Nonadherence in Stroke Survivors

A review of data recorded in the National Health Interview Survey showed that cost-related nonadherence with medication decreased in stroke survivors following the implementation of the ACA.

Mood Stabilizers Associated With Increased Risk for Stroke in Bipolar Disorder

Mood Stabilizers Associated With Increased Risk for Stroke in Bipolar Disorder

Exposure to carbamazepine was associated with the highest risk for stroke, particularly ischemic stroke.

Recommended Levels of Cardiovascular Risk Factors Associated With Cerebral Vessel Density, Flow

Recommended Levels of Cardiovascular Risk Factors Associated With Cerebral Vessel Density, Flow

Investigators evaluated the association between modifiable cardiovascular disease risk factors at recommended levels and white matter hyperintensities and indices of cerebrovascular structure and function.

Characteristics Linked to Arterial Recanalization Following Alteplase Treatment in Ischemic Stroke

Characteristics Linked to Arterial Recanalization Following Alteplase Treatment in Ischemic Stroke

Alteplase was associated with 30.4% success in recanalization, while only 13.3% who did not receive alteplase had success.

Independent Links for Genetics, Lifestyle With Incident Stroke

Independent Links for Genetics, Lifestyle With Incident Stroke

Genetic and lifestyle factors are independently associated with incident stroke among men and women aged 40 to 73 years.

Blood Pressure Screen in Down Syndrome May Help Identify Moyamoya Syndrome Risk

Blood Pressure Screen in Down Syndrome May Help Identify Moyamoya Syndrome Risk

Higher blood pressure was predicted by higher posterior circulation involvement and bilateral disease.

Half of Women to Develop Stroke, Dementia, or Parkinsonism

Half of Women to Develop Stroke, Dementia, or Parkinsonism

One in two women and one in three men will develop dementia, stroke, or parkinsonism during their lifetime.

Pharyngeal Electrical Stimulation Effective for Post-Stroke Dysphagia After Tracheotomy

Pharyngeal Electrical Stimulation Effective for Post-Stroke Dysphagia After Tracheotomy

A higher percentage of PES-treated participants were ready for decannulation compared with those assigned to sham control.

Montreal Cognitive Assessment Predicts Outcomes After Stroke

Montreal Cognitive Assessment Predicts Outcomes After Stroke

The Montreal Cognitive Assessment administered within seven days after stroke can predict long-term cognitive and functional outcome and mortality.

Anodal tDCS Offers Possible Benefit for Improving Item Recall in Post-Stroke Aphasia

Anodal tDCS Offers Possible Benefit for Improving Item Recall in Post-Stroke Aphasia

Following adjustment, the mean change in correctly naming common objects was greater in patients undergoing A-tDCS vs sham tDCS.

Skills-Based Intervention Did Not Cut Systolic BP After Stroke, TIA

Skills-Based Intervention Did Not Cut Systolic BP After Stroke, TIA

A culturally tailored, skills-based educational intervention did not reduce systolic blood pressure at one year after stroke/transient ischemic attack.

Aggressive Blood Pressure Lowering in Intracerebral Hemorrhage May Be Harmful

Aggressive Blood Pressure Lowering in Intracerebral Hemorrhage May Be Harmful

The avoidance of SBP <120 mm Hg in individuals with acute ICH may help prevent cerebral ischemia and neurologic deterioration.

Oxidized Low-Density Lipoprotein May Predict Risk for Recurrent Stroke

Oxidized Low-Density Lipoprotein May Predict Risk for Recurrent Stroke

There are currently no other biomarkers that can predict the risk for recurrent stroke.

Models Predict Intracerebral Hemorrhage Growth

Models Predict Intracerebral Hemorrhage Growth

Models using 4 or 5 predictors have acceptable to good discrimination for determining additional intracerebral hemorrhage growth in patients with acute intracerebral hemorrhage.

Oxygen Desaturation Index Predicts AFib Risk in Ischemic Stroke

Oxygen Desaturation Index Predicts AFib Risk in Ischemic Stroke

Investigators observed a significant association between atrial fibrillation and increasing oxygen desaturation index.

Sleep Duration, Stroke Link Varies With Race, Sex

Sleep Duration, Stroke Link Varies With Race, Sex

The association of sleep duration with incident stroke varies by race and sex.

Risk of Venous Thromboembolism Recurrence High

Risk of Venous Thromboembolism Recurrence High

The risk of recurrence after incident venous thromboembolism is high, particularly among patients with cancer-related venous thromboembolism.

Does Stroke Mechanism in HIV Vary According to Preceding CD4 Counts?

Does Stroke Mechanism in HIV Vary According to Preceding CD4 Counts?

Strokes in people living with HIV are most frequently caused by large artery atherosclerosis.

Hospitals Using Get With the Guidelines-Stroke Program Offer Better Quality Care in Ischemic Stroke

Hospitals Using Get With the Guidelines-Stroke Program Offer Better Quality Care in Ischemic Stroke

The Get With the Guidelines-Stroke program includes measures such as neurologist assessment, rehabilitation evaluation, and education on stroke risk factors.

Net Benefit of Anticoagulants for A-Fib Varies With Stroke Rate

Net Benefit of Anticoagulants for A-Fib Varies With Stroke Rate

There is variation in the net clinical benefit of anticoagulants based on variation in published atrial fibrillation stroke rates.

Electrical Exoskeleton-Assisted Gait Training Effective for Improving Ambulation After Stroke

Electrical Exoskeleton-Assisted Gait Training Effective for Improving Ambulation After Stroke

Patients in the intervention group were fitted with an ambulatory exoskeleton, which works in accordance with the movements of the patient.

No Clear Benefit for Rivaroxaban After Hospital Discharge

No Clear Benefit for Rivaroxaban After Hospital Discharge

Rivaroxaban does not lower risk of symptomatic venous thromboembolism and related death in medical patients after hospital discharge, compared to placebo.

Magnesium Has No Effect on Cognitive Outcomes Following Aneurysmal Subarachnoid Hemorrhage

Magnesium Has No Effect on Cognitive Outcomes Following Aneurysmal Subarachnoid Hemorrhage

In the linear analysis, study investigators found no significant effect of magnesium on cognition.

Thrombolysis With Tenecteplase Is as Safe as Alteplase in Stroke Mimics

Thrombolysis With Tenecteplase Is as Safe as Alteplase in Stroke Mimics

The most frequent stroke mimic diagnoses included migraine and peripheral vertigo.

Transcranial direct current stimulation linked to improved object naming post-stroke

In patients with aphasia, use of anodal transcranial direct current stimulation demonstrated improved object naming compared to sham procedure.

Early Lactic Acidemia Common in Aneurysmal Subarachnoid Hemorrhage

Early Lactic Acidemia Common in Aneurysmal Subarachnoid Hemorrhage

Serum lactate at admission did not correlate with vasospasm or delayed cerebral ischemia development.

Increased Systolic Blood Pressure Variability Linked to Worse Neurologic Outcomes in Intracerebral Hemorrhage

Increased Systolic Blood Pressure Variability Linked to Worse Neurologic Outcomes in Intracerebral Hemorrhage

The primary outcome was an unfavorable neurologic outcome, which was defined as a modified Rankin Scale score of 3 to 6 at 3 months following randomization.

Psychological Distress Linked to Increased Risk of MI, Stroke

Psychological Distress Linked to Increased Risk of MI, Stroke

Psychological distress is associated with myocardial infarction and stroke in men and women.

Early Neurological Deterioration in Intracranial Hemorrhage Linked to Worse Outcomes

Early Neurological Deterioration in Intracranial Hemorrhage Linked to Worse Outcomes

One in 8 patients with ACI experience ultra-early neurological deterioration during ambulance transport and initial evaluation at the emergency department.

Late-Life Blood Pressure Associated With Alzheimer Disease Brain Pathology

Late-Life Blood Pressure Associated With Alzheimer Disease Brain Pathology

Patients with a higher mean systolic blood pressure during follow-up had increased odds for brain infarcts compared with those with lower levels.

Stroke-Code Patients With Low NIHSS Score, No Acute Imaging Findings Often Misdiagnosed

Stroke-Code Patients With Low NIHSS Score, No Acute Imaging Findings Often Misdiagnosed

The investigators observed a high rate of accurate diagnosis for acute cerebral ischemia, hemorrhagic stroke, and stroke mimics in the cohort.

Breastfeeding Linked to Lower Risk of Stroke Post-Menopause

Breastfeeding Linked to Lower Risk of Stroke Post-Menopause

Breastfeeding is associated with a lower risk of stroke among older women, with a stronger correlation for longer duration of breastfeeding.

Poststroke Statin Therapy Associated With Lower Risk for Osteoporosis, Fractures

Poststroke Statin Therapy Associated With Lower Risk for Osteoporosis, Fractures

A variety of underlying mechanisms may be attributed to the role of statins in preventing bone-related disorders.

Lower Socioeconomic Status Linked to Worse Outcomes in Pediatric Arterial Ischemic Stroke

Lower Socioeconomic Status Linked to Worse Outcomes in Pediatric Arterial Ischemic Stroke

The root causes of the disparity reported among families of different income levels are unclear and deserve additional investigation.

Alteplase Non-Superior to Aspirin for Improving 90-Day Functional Outcome in Acute Ischemic Stroke

Alteplase Non-Superior to Aspirin for Improving 90-Day Functional Outcome in Acute Ischemic Stroke

Alteplase may increase the risk for symptomatic intracranial hemorrhage vs aspirin.

Associations Identified Between Stroke Severity, Recovery of Visuospatial Neglect

Associations Identified Between Stroke Severity, Recovery of Visuospatial Neglect

Data from patients with first-ever ischemic right-hemisphere stroke and visuospatial neglect were included.

Clinical, Radiologic Markers Predictive of Cortical Superficial Siderosis in ICH Identified

Clinical, Radiologic Markers Predictive of Cortical Superficial Siderosis in ICH Identified

Investigators identify clinical and neuroimaging markers associated with the presence of cortical superficial siderosis and the risk for recurrent ICH.

Increase in Hypertensive Stroke Survivors After Implementation of New Hypertension Guidelines

Increase in Hypertensive Stroke Survivors After Implementation of New Hypertension Guidelines

Investigators assessed the number of stroke survivors in the US taking antihypertensive medications to treat high blood pressure according to the 2017 ACC/AHA guidelines.

Quality improvement interventions increase adherence to performance measures for stroke in China

Quality improvement interventions were associated with fewer vascular events and less stroke disability over one year of follow up.

Alteplase unlikely to reduce disability after mild stroke without disabling deficits

In this randomized controlled trial, administration of alteplase within 3 hours of mild stoke did not lead to a reduction in disability at 90 days post-stroke compared to aspirin.

Ultra-Early Neurological Deterioration Common in Stroke

Ultra-Early Neurological Deterioration Common in Stroke

Ultra-early neurological deterioration occurs in one in eight ambulance-transported patients with acute cerebrovascular disease.

Patent Foramen Ovale Closure for Stroke Prevention: Key Principles for Clinical Practice

Patent Foramen Ovale Closure for Stroke Prevention: Key Principles for Clinical Practice

Even with thorough testing, declaring a patent foramen ovale as the most likely culprit responsible for a cryptogenic stroke remains a challenge.

High-Sensitivity Blood Test May Help Rule Out Intracranial Injury

High-Sensitivity Blood Test May Help Rule Out Intracranial Injury

A combined test of ubiquitin C-terminal hydrolase-L1 and glial fibrillary acidic protein assay results has high sensitivity for detection of intracranial injury among patients with TBI.

PFO Closure Plus Antiplatelet Tx Advised for Cryptogenic Stroke

PFO Closure Plus Antiplatelet Tx Advised for Cryptogenic Stroke

PFO closure plus antiplatelets recommended over antiplatelet therapy alone for patients younger than 60.

Adhesive Interaction Between Thrombus and Stent Retriever Predominate in Ischemic Stroke

Adhesive Interaction Between Thrombus and Stent Retriever Predominate in Ischemic Stroke

More adhesive-type interactions were observed between the thrombus and stent-retriever after thrombectomy in patients with acute ischemic stroke.

Intracerebral Hemorrhage Risk Decreased With Increasing Cholesterol, Statin Use

Intracerebral Hemorrhage Risk Decreased With Increasing Cholesterol, Statin Use

An inverse relationship was discovered between rising cholesterol levels and decreased risk for intracerebral hemorrhage in new statin users.

World Trade Center-Related PTSD May Up Risk for Stroke, MI in Clean-Up Crew

World Trade Center-Related PTSD May Up Risk for Stroke, MI in Clean-Up Crew

World Trade Center-related PTSD is a risk factor for myocardial infarction and stroke among workers involved in cleaning up the debris.

Five-Year Stroke Rates Lower After PCI Versus CABG

Five-Year Stroke Rates Lower After PCI Versus CABG

Stroke rates are lower at 30 days and five years after percutaneous coronary intervention than after coronary artery bypass grafting.

Bubble-Transcranial Doppler Detects PFOs in Elderly With Cryptogenic TIA

Bubble-Transcranial Doppler Detects PFOs in Elderly With Cryptogenic TIA

Contrast-enhanced transcranial Doppler sonography is a useful noninvasive bedside technique for detecting PFOs among elderly patients with TIA or nondisabling stroke.

Conscious Sedation Increases Risk of Poor Functional Outcome, Mortality Following Stroke Treatment

Conscious Sedation Increases Risk of Poor Functional Outcome, Mortality Following Stroke Treatment

Investigators assessed the impact of conscious sedation on outcomes in patients undergoing intra-arterial treatment for acute ischemic stroke.

Taking Multivitamins/Minerals Doesn't Improve CVD Outcomes

Taking Multivitamins/Minerals Doesn't Improve CVD Outcomes

Multivitamin/mineral supplementation seems not to be associated with cardiovascular disease outcomes.

Apixaban Is Safest Direct Oral Anticoagulant Versus Warfarin

Apixaban Is Safest Direct Oral Anticoagulant Versus Warfarin

Apixaban seems to be the safest direct oral anticoagulant compared with warfarin.

Transfeminine Persons Have Increased VTE Incidence

Transfeminine Persons Have Increased VTE Incidence

Transfeminine individuals have increased rates of VTE compared with cisgender men and cisgender women, with more pronounced differences for those initiating hormone therapy.

Cerebral Infarction in Meningitis Linked to Genetic Variant

Cerebral Infarction in Meningitis Linked to Genetic Variant

The prospective study was performed in patients ≥16 years of age with community-acquired bacterial meningitis.

Half of Cardiovascular Events Occur 2 to 5 Years After Transient Ischemic Attack, Stroke

Half of Cardiovascular Events Occur 2 to 5 Years After Transient Ischemic Attack, Stroke

For patients who experienced a TIA or minor stroke, the rate of a composite of stroke, acute coronary syndrome, or death from cardiovascular causes is 12.9 percent at five years.

Combo Therapy With Probucol May Prevent Cardiovascular Events in Stroke Patients at Risk for ICH

Combo Therapy With Probucol May Prevent Cardiovascular Events in Stroke Patients at Risk for ICH

A team of investigators sought to assess the efficacy and safety of cilostazol vs aspirin, both with and without probucol, a cholesterol-lowering agent, in Asian patients with ischemic stroke.

Transcranial Doppler Ultrasound Timing Critical for Beneficial Outcomes Following Stroke Thrombolysis

Transcranial Doppler Ultrasound Timing Critical for Beneficial Outcomes Following Stroke Thrombolysis

A team of investigators sought to assess whether the use of diagnostic transcranial Doppler ultrasound may delay initiation of intravenous thrombolysis in patients experiencing acute stroke.

LA Appendage Occlusion Reduces Post-Cardiac Surgery Thromboembolism Risk

LA Appendage Occlusion Reduces Post-Cardiac Surgery Thromboembolism Risk

A retrospective cohort study was conducted to assess the effect of surgical left atrial appendage occlusion on risk for readmission due to thromboembolism in older patients.

Cerebral Microbleeds as Biomarker for Hemorrhage Risk in Anticoagulated AFib

Cerebral Microbleeds as Biomarker for Hemorrhage Risk in Anticoagulated AFib

Investigators assessed the presence of cerebral microbleeds as a biomarker for identifying patients at increased risk for intracranial hemorrhage as a result of anticoagulation for atrial fibrillation.

Rivaroxaban Use in Older Patients: Does Age Influence Safety, Efficacy?

Rivaroxaban Use in Older Patients: Does Age Influence Safety, Efficacy?

Data from large Phase 3 studies showed that treatment with rivaroxaban was found to be safe and effective in older patients.

Post-Stroke Oral Anticoagulation Reduces Recurrent Stroke Risk in Atrial Fibrillation

Post-Stroke Oral Anticoagulation Reduces Recurrent Stroke Risk in Atrial Fibrillation

Investigators retrospectively reviewed treatment patterns and long-term outcomes in 30,626 patients with ischemic stroke and AF who had these data recorded in 4 Danish healthcare registries.

Tranexamic Acid Provides Short-Term, But Not Long-Term, Benefits Following Intracerebral Hemorrhage

Tranexamic Acid Provides Short-Term, But Not Long-Term, Benefits Following Intracerebral Hemorrhage

Patients with intracerebral hemorrhage who were admitted to acute stroke units were randomly assigned to either 1 gram intravenous tranexamic acid followed by an 8-hour infusion of 1 gram tranexamic acid or matched placebo.

Dual Therapy With Clopidogrel, Aspirin Reduces Risk for Major Ischemic Events

Dual Therapy With Clopidogrel, Aspirin Reduces Risk for Major Ischemic Events

At 90-day follow-up, the data and safety monitoring board halted the trial after it found that approximately 84% of patients had experienced both a lower risk and higher risk for major ischemic events and major hemorrhage compared with aspirin only, respectively.

Prevention of Recurrent Stroke Similar With Rivaroxaban, Aspirin

Prevention of Recurrent Stroke Similar With Rivaroxaban, Aspirin

During a median follow-up period of 11 months, a total of 172 and 160 patients in the rivaroxaban and aspirin groups, respectively, experienced a recurrent stroke of any type or a systemic embolism.

Cardiovascular Risks Persist Following Transient Ischemic Attack or Minor Stroke

Cardiovascular Risks Persist Following Transient Ischemic Attack or Minor Stroke

Approximately half of composite outcome events and up to half of the stroke events occurred during the second through fifth years of the analysis.

Lack of superiority of rivaroxaban for secondary prevention of embolic stroke of undetermined source

At a median follow-up of eleven months, rivaroxaban was not superior to aspirin for prevention of secondary stroke after an initial primary embolic stroke of undetermined source.

Continued Anticoagulation in Resolved AFib May Help Reduce Stroke Risk

Continued Anticoagulation in Resolved AFib May Help Reduce Stroke Risk

Investigators conducted 2 retrospective cohort studies to determine whether patients with resolved AF were at an increased risk for stroke or TIA and all-cause mortality compared with matched controls with unresolved AF.

New Coagulation Monitoring Device Allows for Wireless Reporting of INR Results

New Coagulation Monitoring Device Allows for Wireless Reporting of INR Results

Roche is expected to launch the CoaguChek Vantus system, the first Bluetooth-enabled, self-testing device for coagulation monitoring, this summer.

Disparities for Risk of Recurrent Hemorrhagic Stroke Unexplained

Disparities for Risk of Recurrent Hemorrhagic Stroke Unexplained

Black and Hispanic patients are at higher risk for stroke recurrence than white patients.

Under New Guidelines, More Stroke Survivors With Hypertension Diagnosis

Under New Guidelines, More Stroke Survivors With Hypertension Diagnosis

Under the 2017 ACC/AHA hypertension guidelines, there would be a substantial increase in the proportions of stroke survivors with hypertension.

MRI pattern selects patients with unknown stroke time who benefit from thrombolysis

Stroke patients with unknown time of stroke onset and DWI-FLAIR mismatch indicative of a stroke within the prior 4.5 hours who were randomized to alteplase were more likely to have a favorable outcome at 90 days than those receiving placebo.

Stroke Survivors Have Higher Risk for Subsequent Seizures Than General Population

Stroke Survivors Have Higher Risk for Subsequent Seizures Than General Population

At 8 years, the cumulative rate of any hospitalization or emergency department visit for seizure was higher among patients with stroke vs the general population.

Women Face Marginally Increased Risk for Poor Functional Outcomes After Stroke

Women Face Marginally Increased Risk for Poor Functional Outcomes After Stroke

Although women demonstrated greater participation restriction compared with men in the unadjusted analysis, there was no difference between men and women after accounting for age, stroke severity, and prestroke dependency.

Clopidogrel Plus Aspirin Cuts Ischemic Events in Stroke, TIA

Clopidogrel Plus Aspirin Cuts Ischemic Events in Stroke, TIA

The combination of clopidogrel and aspirin is associated with reduced risk of major ischemic events but increased risk of major hemorrhage among patients with minor ischemic stroke.

Alteplase Good for Ischemic Stroke With Unknown Onset Time

Alteplase Good for Ischemic Stroke With Unknown Onset Time

For patients with ischemic stroke with an unknown time of onset, intravenous alteplase is associated with better functional outcome than placebo.

Prediction Algorithm Stratifies ICH Patients at Risk for Hematoma Expansion

Prediction Algorithm Stratifies ICH Patients at Risk for Hematoma Expansion

While developing the hematoma expansion prediction score, associations between hematoma expansion and blend sign, any intrahematoma hypodensity, and time from onset to noncontrast computed tomography <2.5 hours were found.

Congenital Heart Disease, Hispanic Ethnicity Associated With Increased Mortality in Pediatric Arterial Ischemic Stroke

Congenital Heart Disease, Hispanic Ethnicity Associated With Increased Mortality in Pediatric Arterial Ischemic Stroke

The investigators were unable to determine which type of congenital heart disease or which type of ventricular assist device, if used, played a role in mortality outcomes.

Tenecteplase Improves Reperfusion and Functional Outcome in Ischemic Stroke

Tenecteplase Improves Reperfusion and Functional Outcome in Ischemic Stroke

The findings from this trial are limited to only ischemic stroke patients with large-vessel occlusion who are deemed appropriate for thrombolysis.

Ceftriaxone More Cost-Effective Than Standard Care for Post-Stroke Infection Prevention

Ceftriaxone More Cost-Effective Than Standard Care for Post-Stroke Infection Prevention

There were no differences between the ceftriaxone and standard care groups in terms of institutional care resources, out-of-pocket expenses, or productivity losses.

Sickle Cell Trait Does Not Reliably Predict Ischemic Stroke in African Americans

Sickle Cell Trait Does Not Reliably Predict Ischemic Stroke in African Americans

Sickle cell trait is not associated with ischemic stroke and should not be relied upon as a sole predictor of stroke in African Americans.

Poststroke Neurocognitive Disorder Prevalent in Acute Stroke

Poststroke Neurocognitive Disorder Prevalent in Acute Stroke

A shortened summary cognitive score consisting of action speed, executive function, and language may help diagnose poststroke NCD.

Frequency of Sauna Bathing Linked to Reduced Stroke Risk

Frequency of Sauna Bathing Linked to Reduced Stroke Risk

For adults, frequent sauna bathing is associated with reduced risk of future stroke.

ARISE II Demonstrates Improved Reperfusion With EmboTrap in Ischemic Stroke

ARISE II Demonstrates Improved Reperfusion With EmboTrap in Ischemic Stroke

The lack of a comparator group as well as the relatively small patient sample represents potential limitations of this study.

Cerebral Microbleeds Do Not Predict 3-Month Death or Disability in Intracerebral Hemorrhage

Cerebral Microbleeds Do Not Predict 3-Month Death or Disability in Intracerebral Hemorrhage

Investigators performed a pre-planned secondary analysis of the open-label, randomized Antihypertensive Treatment of Acute Cerebral Hemorrhage 2 study, specifically on the magnetic resonance images obtained during the intensive blood pressure lowering portion of the trial.

Infarct Volume Predictive of Functional Outcome After Acute Ischemic Stroke

Infarct Volume Predictive of Functional Outcome After Acute Ischemic Stroke

Variations in reperfusion rates as well as MRI assessments among included studies represent possible limitations of this meta-analysis.

Previous Stroke Tied to Higher Risks in Aortic Valve Replacement

Previous Stroke Tied to Higher Risks in Aortic Valve Replacement

For patients undergoing surgical aortic valve replacement, previous stroke is a risk factor for recurrent ischemic stroke and major adverse cardiovascular events.

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